DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CoRest and mideasa

DIOPT Version :9

Sequence 1:	NP_001188671.1	Gene:	CoRest / 32941	FlyBaseID:	FBgn0261573	Length:	824	Species:	Drosophila melanogaster
Sequence 2:	XP_005160646.1	Gene:	mideasa / 569908	ZFINID:	ZDB-GENE-041001-151	Length:	1016	Species:	Danio rerio

Alignment Length:	255	Identity:	56/255 - (21%)
Similarity:	106/255 - (41%)	Gaps:	41/255 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 VPGAGTPESSDDDNSTKRNGKS-----------KAKQSEYEEKIRVGRDYQAVCPPLVPEAERRP 113
            :|...||.|:  ..|..|:..|           :|.....|..|.:|..|||..|.|:..:....
Zfish   615 LPPPPTPRSA--SRSLLRSSSSDITPPAPPLIGEATPVSLEPHINIGSKYQAEIPELLDRSSALK 677

  Fly   114 EQMNERALLVWSP-TKEIPDLKLEEYISVAKEKYGYNG----EQALGMLFWHKHDLERAV----- 168
            :|  .:|.|||.| :....:.:::..:::......|.|    |.|:..|...|.|:..|:
Zfish   678 DQ--HKATLVWQPESSASQETRVDNLMNLVCSSVMYGGGTNTELAMHCLHECKGDVMEALEMMML 740

  Fly   169 --------MDLANF-TPFPDEWTIEDKVLFEQAFQFHGKSFHRIRQMLPDKSIASLVKYYYSWKK 224
                    ..|||: ....|.|:.::|..|.:....:.|.|..:::::..|::|..|::||::||
Zfish   741 KNPIFSWNHQLANYHYAGSDYWSADEKRYFNKGISAYTKDFFMVQKLVRTKTVAQCVEFYYTYKK 805

  Fly   225 ----TRHRSSAM--DRQEKAIKAVVKDGSENGSEVGSNEE-SDNDDKKGHGTNSTINTID 277
                ||:.:...  ...|::|..:....::..::....|| .|:.|::......|:...|
Zfish   806 QARVTRNGTCTYGPSDPEESIPVMNARQADKENDCKQQEEMEDSVDERLQDVTKTLQQSD 865

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CoRest	NP_001188671.1	ELM2	92..144	CDD:279754	13/52 (25%)
		SANT	179..225	CDD:197842	13/49 (27%)
		SANT	180..224	CDD:304392	10/43 (23%)
		SANT	540..582	CDD:238096
mideasa	XP_005160646.1	ELM2	656..707	CDD:279754	13/52 (25%)
		SANT	760..805	CDD:197842	11/44 (25%)
		SANT	762..805	CDD:304392	10/42 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810