Protein Alignment CoRest and rcor3

DIOPT Version :10

• Sequence 1: NP_001188671.1
• Gene: CoRest / 32941
• FlyBaseID: FBgn0261573
• Length: 824
• Species: Drosophila melanogaster
• Sequence 2: NP_001038494.1
• Gene: rcor3 / 563808
• ZFINID: ZDB-GENE-050208-371
• Length: 547
• Species: Danio rerio
• Alignment Length: 739
• Identity: 206/739 - (27%)
• Similarity: 312/739 - (42%)
• Gaps: 253/739 - (34%)

  Fly    29 GGVTNSASLVGSGNNSGHSGNANANEKTTTAVPGAGTPESSDDDNSTKRNGKSKAKQSEYEEKIR 93
            |.:...:..:|.|.::|....:||:.       |..:.||..||              |::..:|
Zfish     3 GMMDKGSEYLGKGRSNGTKSPSNASN-------GHFSDESGSDD--------------EHDVGMR 46

  Fly    94 VGRDYQAVCPPLVPEAERRPEQMNERALLVWSPTKEIPDLKLEEYISVAKEKYGYNGEQALGMLF 158
            ||.||||..|...|.:.:..:: :...:|||||...|.|.||:|||::||||:|||.||||||||
Zfish    47 VGSDYQANIPEFDPGSSKYSDK-DSGGMLVWSPHHTILDSKLDEYIAIAKEKHGYNVEQALGMLF 110

  Fly   159 WHKHDLERAVMDLANFTPFPDEWTIEDKVLFEQAFQFHGKSFHRIRQMLPDKSIASLVKYYYSWK 223
            ||||::|:::.||.||||||||||:||||||||||.|||||||||:||||||||:||||||||||
Zfish   111 WHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKSISSLVKYYYSWK 175

  Fly   224 KTRHRSSAMDRQEKAIKAVVKDGSENGSEVGSNEESDNDDKKGHGTNSTINTIDATTTSTNNSTT 288
            |||.|:|.||||
Zfish   176 KTRSRTSLMDRQ----------------------------------------------------- 187

  Fly   289 NSNTTTPANIIANTINSNHSSSNSGGGGNINNNGEENIQAVGGSNTI-SNTSNNDMDAEQLSLFA 352
                   |..:||                 .||.:|:.:.:..:|.: :|.|:.|...|
Zfish   188 -------ARKLAN-----------------RNNQDESEEEMEEANPVEANDSDYDPTKE------ 222

  Fly   353 GNAQIEEMMALGLAADRAIGANGGNNNNNGEMGGDPGLMRRMVVGGFCKICNVVCHVLHDSPLGR 417
                          |.:.:.........:.::|                             :||
Zfish   223 --------------AKKEVNTPAEPQTLSSKIG-----------------------------MGR 244

  Fly   418 MCKSCHTHWRRTGNRRPISGPEGNAPRRSTHNCAATADRSKRKPPKGMYINHDDLTALASCGNPS 482
            .......|...|                         .|||.:||||||:..:|:.|: ||.:.:
Zfish   245 RDHQTLQHRHHT-------------------------QRSKCRPPKGMYLTQEDVVAI-SCSSSA 283

  Fly   483 L--YLAERERKLTALMAEIQKNRQVMEQLDKECETINVDDVLSKPAAANTESAQPRISARWLPDE 545
            .  .|.:.:.:|.:|..::|..:|:...|.::.|. .:|: |..|     |..| :|:|||..||
Zfish   284 ANSVLRQLDMELVSLKRQVQNAKQLNSGLKQKIED-GIDE-LRLP-----ECTQ-KINARWTTDE 340

  Fly   546 IQVALLAIREYGKNFPTIAKVVATKTEAHVRTFYLNNRRRYNLDQIVKEYEA------------- 597
            ..:|:..:|:|||:|..||.|:..||...|:.|::|.|||:|||::::|:||
Zfish   341 QLLAVQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLDEVLQEWEAEQGTRTPNGDGAN 405

  Fly   598 ----GKSEESGAEEQTEPAVDAAAAGAATASAPSAADSTSAASATADRKQSTENSNNGVETMQES 658
                ||:..:.:.:.|:...:......|...:|..:.|:|...:::...|...      ..::.|
Zfish   406 SGEDGKTSNASSGKSTDEEEEEGQVSLACGPSPVVSSSSSCPPSSSSSLQQPP------PLLRPS 464

  Fly   659 LP--------------------------------KKEDPKKPELAAAVLKIGVAEAADAVATVAS 691
            ||                                :..:|..|       ::....||....:.|:
Zfish   465 LPATPALHRQPPPLQQQARFLQPRPALHQPPPLIRPSNPVPP-------RLNPRPAAPLAPSTAN 522

  Fly   692 STASG-----VIGAATSASKPSTS 710
            :.|:|     ::| ..||..||:|
Zfish   523 TPAAGQQPPALLG-IQSAETPSSS 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CoRest	NP_001188671.1	ELM2	92..144	CDD:460214	22/51 (43%)
		SANT	180..224	CDD:473887	39/43 (91%)
		Myb_DNA-binding	540..583	CDD:459731	18/42 (43%)
rcor3	NP_001038494.1	ELM2	45..96	CDD:460214	22/51 (43%)
		SANT	132..176	CDD:473887	39/43 (91%)
		Myb_DNA-binding	335..378	CDD:459731	18/42 (43%)
		PHA03247	<467..532	CDD:223021	7/71 (10%)