DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CoRest and mideasb

DIOPT Version :9

Sequence 1:	NP_001188671.1	Gene:	CoRest / 32941	FlyBaseID:	FBgn0261573	Length:	824	Species:	Drosophila melanogaster
Sequence 2:	XP_009291493.1	Gene:	mideasb / 560411	ZFINID:	ZDB-GENE-131121-13	Length:	1095	Species:	Danio rerio

Alignment Length:	415	Identity:	93/415 - (22%)
Similarity:	162/415 - (39%)	Gaps:	92/415 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 ANANEKTTTAVPGAGTPES---------SDDDNSTKRNGKSKAKQSEYEEKIRVGRDYQAVCPPL 105
            |.||.:   .:|...||:|         |.|......:..|:|.....|.:|.:|..|||.
Zfish   682 AAANNQ---VLPPPATPKSATRSLLRSNSSDITPPVLSAISEATPVSIEPRINIGVRYQAE---- 739

  Fly   106 VPEAERRPEQMNE--RALLVWSPTKEIPDL--------KLEEYISVAKEKY----GYNGEQALGM 156
            |||...|...:::  :|.|||:|   :|||        |:.:.:.:|....    |.|.|.|:..
Zfish   740 VPELRERSAALHDLHKAELVWAP---LPDLEASAQQQQKVNDLMHLACSSALFGGGTNQELAMHC 801

  Fly   157 LFWHKHDLERAVMDL-------ANFTPF-------PDEWTIEDKVLFEQAFQFHGKSFHRIRQML 207
            |:..|.|:...:..|       :...|.       .|.||.|::.||.:....:.|.|..:::::
Zfish   802 LYECKGDIMGTLTHLLLKKNIFSKSHPLADYHYSGSDSWTPEERRLFNKGIATYKKDFFMVQKLV 866

  Fly   208 PDKSIASLVKYYYSWKKTRH--RSSAM---DRQEKAIKAVVKDGSENGS--EVGSNEESD----- 260
            ..|::|..|::||::||...  |:..:   :.:....|...::..:|.|  ::.|.:|.:
Zfish   867 SSKTVAQCVEFYYTYKKQVKIGRNGTLVYGETEPLETKPTTEEEVDNKSSQKLESRKEDEESRKW 931

  Fly   261 -------NDDKKGHGTNS---TINTIDATTTSTNNSTTNSNT----------TTPANIIANTINS 305
                   .:|..|..|.|   |.|.......|..|||.:.:|          ..|:...::|...
Zfish   932 EGSCDRKQEDSPGRVTQSLQATENAAAVLVLSQENSTRHPSTLGVSHPPHPPQPPSKSRSDTAAR 996

  Fly   306 NHSSSNSGGGGNINNNGEENIQAVG------GSNTISNTSNNDMDAEQLSLFAGNAQIEEMMAL- 363
            ....||: |.|..|..||...:..|      .|.:....|:.:.:.:..:|....|:.....||
Zfish   997 KTGPSNT-GKGQTNQEGEFPCKKCGRIFYKVKSRSAHMKSHAEAEKKAAALRQREAEQRAAAALL 1060

  Fly   364 -----GLAADRAIGANGGNNNNNGE 383
                 |..||:..|....:::::.|
Zfish  1061 AAQQNGAMADQGRGRRASSDDSSDE 1085

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CoRest	NP_001188671.1	ELM2	92..144	CDD:279754	19/61 (31%)
		SANT	179..225	CDD:197842	14/45 (31%)
		SANT	180..224	CDD:304392	12/43 (28%)
		SANT	540..582	CDD:238096
mideasb	XP_009291493.1	ELM2	730..785	CDD:279754	19/61 (31%)
		SANT	838..883	CDD:197842	13/44 (30%)
		SANT	839..883	CDD:304392	12/43 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810