DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CoRest and Mier2

DIOPT Version :9

Sequence 1:	NP_001188671.1	Gene:	CoRest / 32941	FlyBaseID:	FBgn0261573	Length:	824	Species:	Drosophila melanogaster
Sequence 2:	XP_038935335.1	Gene:	Mier2 / 362841	RGDID:	1307278	Length:	664	Species:	Rattus norvegicus

Alignment Length:	270	Identity:	71/270 - (26%)
Similarity:	110/270 - (40%)	Gaps:	57/270 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 PSPNTHTTGGV--TNSASLVGSGNNSGHSGNANANEKTTTAVPGAGTPESSDDDNSTKRNGKSKA 83
            ||..:|....:  ..|.|...||:|                  |.|:..|||.:.......|.|
  Rat   267 PSVTSHEASDLFHNQSGSRFLSGDN------------------GPGSSASSDTEEDALPANKCK- 312

  Fly    84 KQSEYEEKIRVGRDYQAVCPPLVPEAERRPEQM--NERALLVWSPTKEIPDLKLEEYISVA---- 142
                  ::|.||..:||....|  ...|..:::  ||..|| |||| .:|:.::||::..|
  Rat   313 ------KEIMVGPQFQADLNIL--HLNRHCDKIYENEDQLL-WSPT-VLPEREVEEFLYRAVKRR 367

  Fly   143 -KEKYG---------YNGEQALGMLFWHKHDLERAVMDLA-NFTPFPD---EWTIEDKVLFEQAF 193
             :|..|         .:.||||..|.....::|.|:..|. |.....|   .|:.|:...||..|
  Rat   368 WQEMAGPQIPEGEVVKDSEQALYELVKCNFNVEEALRRLRFNVKVIRDGLCAWSEEECRNFEHGF 432

  Fly   194 QFHGKSFHRIR-QMLPDKSIASLVKYYYSWKKTRHRSSAMDRQEKAIKAVVKDGSENGSEVGSNE 257
            :.|||:||.|: ..:..:|:...|:|||.|||:........:.....:..|..|:.:     :.:
  Rat   433 RVHGKNFHLIQANKVRTRSVGECVEYYYLWKKSERYDYFAQQTRLGRRKFVSSGTTD-----TEQ 492

  Fly   258 ESDNDDKKGH 267
            :.|..|..||
  Rat   493 DLDGLDPDGH 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CoRest	NP_001188671.1	ELM2	92..144	CDD:279754	19/58 (33%)
		SANT	179..225	CDD:197842	19/49 (39%)
		SANT	180..224	CDD:304392	17/44 (39%)
		SANT	540..582	CDD:238096
Mier2	XP_038935335.1	ELM2	315..365	CDD:396160	19/53 (36%)
Mier2	XP_038935335.1	SANT_MTA3_like	420..464	CDD:212559	17/43 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910