DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CoRest and CG1620

DIOPT Version :9

Sequence 1:	NP_001188671.1	Gene:	CoRest / 32941	FlyBaseID:	FBgn0261573	Length:	824	Species:	Drosophila melanogaster
Sequence 2:	NP_001260777.1	Gene:	CG1620 / 35678	FlyBaseID:	FBgn0033183	Length:	586	Species:	Drosophila melanogaster

Alignment Length:	494	Identity:	100/494 - (20%)
Similarity:	160/494 - (32%)	Gaps:	189/494 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RNGRRSRGPSPNT------------HTTGGVTNSASLVGSGNNSGHSGNANANEKTTTAVPGAGT 65
            |:|..||.....|            ||:...::|.|.:     ..|.|.....|....|...|..
  Fly   136 RSGSSSRRARRATKRQYQELDTEMAHTSTSTSSSTSQL-----EKHDGIDQEEEPKEEADKLASP 195

  Fly    66 PESS-----DDDNSTKRNGKSKAKQS-------------------------------------EY 88
            |||.     |.:::.|..|..|..:|                                     |.
  Fly   196 PESGEASSVDTEDAQKYEGIKKQHRSHLLDLYPDESFVDLAPTCGEETERFTPLQTLFDEVEAEE 260

  Fly    89 EEK-----------IRVGRDYQAVCPP-LVPEAERRPEQMNERALLVWSPTKEIPDLKLEEYISV 141
            ||:           |.||.||||..|. |....:..|.:..::  |:|.|: ::.:.::|||::.
  Fly   261 EEESESELDDARKIIMVGHDYQAEIPEGLSQYGDILPYENEDQ--LIWEPS-QVSEREVEEYLAK 322

  Fly   142 AKE-------------KYGYNG---------------------------------------EQAL 154
            .:|             ..|..|                                       ||||
  Fly   323 IQETRSIVPPDDGSETTAGEEGAATGATIEPPAPITAPATPPRAPLATSGAGDQELVVKDNEQAL 387

  Fly   155 GML----FWHKHDLERAVMDLANFTPFPDEWTIEDKVLFEQAFQFHGKSFHRIRQ-MLPDKSIAS 214
            .:|    :..|..|.|..|::...|.....|:.::.:.||:..|..||.|::||| .:..:::..
  Fly   388 HLLVQCGYDFKEALRRKRMNVLPLTDTMSSWSEDECLKFEEGIQRFGKDFYQIRQNQVRTRTMRE 452

  Fly   215 LVKYYYSWKKTRHRSSAMDRQEKAIKAVVKDGSENGSEVGSNEESDNDDKKGHGTNSTINTIDA- 278
            ||.:||.|||:..|..:.                                   ..|.||:.:|.
  Fly   453 LVHFYYLWKKSERRDQSF-----------------------------------ALNDTIDHMDVF 482

  Fly   279 -TTTSTNNSTTNSNTTTPANIIANTINSNHS----SSNSGGGGNINNNGEENIQA---------- 328
             ......|.:.|.|   .|.|::.|.|||.|    |||....|:::...::.|.:
  Fly   483 INEAGGGNGSGNGN---GAGIVSGTANSNGSCSPHSSNGHSNGDLSALEKDTIASPRKPASKSYS 544

  Fly   329 -VGGSNTISNTSNND---MDAEQLSLFAGNAQIEEMMAL 363
             :.||..:.|.|..:   ..:..|.|...:..:||..:|
  Fly   545 IMTGSQAVGNPSGGNRKRCSSASLPLEDEDNNVEEEPSL 583

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CoRest	NP_001188671.1	ELM2	92..144	CDD:279754	16/52 (31%)
		SANT	179..225	CDD:197842	16/46 (35%)
		SANT	180..224	CDD:304392	15/44 (34%)
		SANT	540..582	CDD:238096
CG1620	NP_001260777.1	ELM2	275..320	CDD:279754	15/47 (32%)
		SANT	417..463	CDD:197842	16/45 (36%)
		SANT_MTA3_like	417..462	CDD:212559	15/44 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1194
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810