Protein Alignment CoRest and Rcor2

DIOPT Version :9

• Sequence 1: NP_001188671.1
• Gene: CoRest / 32941
• FlyBaseID: FBgn0261573
• Length: 824
• Species: Drosophila melanogaster
• Sequence 2: XP_038965938.1
• Gene: Rcor2 / 305811
• RGDID: 1359467
• Length: 575
• Species: Rattus norvegicus
• Alignment Length: 669
• Identity: 193/669 - (28%)
• Similarity: 275/669 - (41%)
• Gaps: 235/669 - (35%)

  Fly    47 SGNANANEKTTTAVPGAGTPESSDDDNSTKRNGKSKAKQSEYEEKIRVGRDYQAVCPPLVPEAER 111
            :|:...:.......|..|.|.|.||.:..:.:....|.....:..||||.:||||.|...||:..
  Rat    10 AGSGILSRSRAKTAPNGGQPHSEDDSSEEEHSHVLTASPGSTDSMIRVGTNYQAVIPECKPESPA 74

  Fly   112 RPEQMNERALLVWSPTKEIPDLKLEEYISVAKEKYGYNGEQALGMLFWHKHDLERAVMDLANFTP 176
            |......:.:|||||...:.|.||::||::||||:|||.|||||||.|||||:|:::.|||||||
  Rat    75 RYSNKELKGMLVWSPNHCVSDAKLDKYIAMAKEKHGYNIEQALGMLLWHKHDVEKSLADLANFTP 139

  Fly   177 FPDEWTIEDKVLFEQAFQFHGKSFHRIRQMLPDKSIASLVKYYYSWKKTRHRSSAMDRQEKAIKA 241
            ||||||:||||||||||.||||.|.||:||||||.|.|||||||||||||.|:|.||||.:.:.
  Rat   140 FPDEWTVEDKVLFEQAFGFHGKCFQRIQQMLPDKLIPSLVKYYYSWKKTRSRTSVMDRQARRLG- 203

  Fly   242 VVKDGSENGSEVGSNEESDNDD-KKGHGTNSTINTIDATTTSTNNSTTNSNTTTPANIIANTINS 305
                        |..::.|:|: ::|.|..|
  Rat   204 ------------GRKDKEDSDELEEGRGAVS---------------------------------- 222

  Fly   306 NHSSSNSGGGGNINNNGEENIQAVGGSNTISNTSNNDMDAEQLSLFAGNAQIEEMMALGLAADRA 370
                           .||.:.
  Rat   223 ---------------EGEPDT-------------------------------------------- 228

  Fly   371 IGANGGNNNNNGEMGGDPGLMRRMVVGGFCKICNVVCHVLHDSPLGRMCKSCHTHWRRTGNRRPI 435
                           |||   :|              ..|...||               |.||.
  Rat   229 ---------------GDP---KR--------------EPLPSRPL---------------NARPG 246

  Fly   436 SGPEGNAPRRSTHNCAATADRSKRKPPKGMYINHDDLTALASCGNP---SLYLAERERKLTALMA 497
            .|.:.....:..|:..    |::|:||||||::.:.|||::  |:|   :|.|...:.:|.:|..
  Rat   247 PGKKEIQVSQYRHHPL----RTRRRPPKGMYLSPEGLTAVS--GSPDLANLTLRGLDSQLISLKR 305

  Fly   498 E-------------------------------------------IQKNRQVMEQLDKECETINVD 519
            :                                           :|..:|....|.:..|. .:|
  Rat   306 QVLGIKLRSELVAGKGVPDVTCMYMIYVSAACVPWCPCASFYLYVQSMKQTNSSLRQALEG-GID 369

  Fly   520 DVLSKPAAANTESAQPRISARWLPDEIQVALLAIREYGKNFPTIAKVVATKTEAHVRTFYLNNRR 584
            .:  :|..|||     :.::||..||..:|:.|||.|||:|..||:|:..||...|:||:::.||
  Rat   370 PL--RPPEANT-----KFNSRWTTDEQLLAVQAIRRYGKDFGAIAEVIGNKTLTQVKTFFVSYRR 427

  Fly   585 RYNLDQIVKEYEAGKSEESGAEEQTEPAVDAAAAGAATASAPSAADSTSAASATADRKQSTENSN 649
            |:||:::::|:||   |:.||.....|..:|.......|:|....|.....|.:.
  Rat   428 RFNLEEVLQEWEA---EQDGAPTAPVPVEEARRGAPVPATALEEDDEVQITSVST---------- 479

  Fly   650 NGVETMQESLPKKEDPKKP 668
                    |:|:...|..|
  Rat   480 --------SVPRSVPPAPP 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CoRest	NP_001188671.1	ELM2	92..144	CDD:279754	23/51 (45%)
		SANT	179..225	CDD:197842	38/45 (84%)
		SANT	180..224	CDD:304392	36/43 (84%)
		SANT	540..582	CDD:238096	20/41 (49%)
Rcor2	XP_038965938.1	ELM2	55..107	CDD:396160	23/51 (45%)
		SANT	143..187	CDD:419695	36/43 (84%)
		Myb_DNA-binding	383..426	CDD:395191	20/42 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354556
Domainoid	1	1.000	51	1.000	Domainoid score	I11280
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	299	1.000	Inparanoid score	I2619
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D287298at33208
OrthoFinder	1	1.000	-	-		FOG0001182
OrthoInspector	1	1.000	-	-		otm45420
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR16089
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1336
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.000