DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CoRest and T07F8.4

DIOPT Version :9

Sequence 1:	NP_001188671.1	Gene:	CoRest / 32941	FlyBaseID:	FBgn0261573	Length:	824	Species:	Drosophila melanogaster
Sequence 2:	NP_495478.1	Gene:	T07F8.4 / 174173	WormBaseID:	WBGene00020320	Length:	345	Species:	Caenorhabditis elegans

Alignment Length:	297	Identity:	69/297 - (23%)
Similarity:	105/297 - (35%)	Gaps:	83/297 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 PSPNTHTTGGVTNSASLVGSGNNSGHSGNANANEKTTTAVPGAGTPESSDDDNSTKRNGKSKAKQ 85
            |:.|:......|..|.     .|.|.|.:|.|....:|......:....|||:..........|:
Worm    67 PAENSSANNEDTEIAE-----ENVGESSSAAAEPHDSTIFDMGNSMSGFDDDDDDYAPPPDPWKR 126

  Fly    86 SEYEEKIRVGRDYQAVCPPLVPEAERRPEQMNERALLVWS------PTKEIPDLKLEEYISVAKE 144
            |     |||.........||..||... |...|...::|:      |:.|:.|..|::.:.:.|.
Worm   127 S-----IRVDPVLFQADVPLFNEATVE-ESAREDDTILWTIDQTNQPSDEVIDNYLKDVVGLRKA 185

  Fly   145 ---------KYGYNGEQALGMLFWHKHDLERAVMDLANFTPFP----------------DEWTIE 184
                     ....:.|.||..|:....|.|:|....    |||                ||   .
Worm   186 HDQPCPPAGTESRDDEDALCALYRSNFDTEKAKESF----PFPHINAPFRTVRSDALGFDE---S 243

  Fly   185 DKVLFEQAFQFHGKSFHRIRQM-LPDKSIASLVKYYYSWKKT------------------RHRSS 230
            :...||::.:.:||.|..||:: ||.:.:..|::|||.||.|                  .|.|:
Worm   244 EAKAFEESLELYGKDFSLIRRLRLPYRKVGELIEYYYQWKLTPGYRVWRDAHPQHAPVVQPHLSA 308

  Fly   231 AMDRQEKAIKAVVKDGSENG---------SEVGSNEE 258
            |..:|      |.:...:||         ||..::||
Worm   309 AWHQQ------VAQLEDQNGQTGFVEASFSEPSTSEE 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CoRest	NP_001188671.1	ELM2	92..144	CDD:279754	14/57 (25%)
		SANT	179..225	CDD:197842	17/46 (37%)
		SANT	180..224	CDD:304392	15/44 (34%)
		SANT	540..582	CDD:238096
T07F8.4	NP_495478.1	ELM2	128..179	CDD:366648	14/51 (27%)
T07F8.4	NP_495478.1	SANT_MTA3_like	240..283	CDD:212559	15/45 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810