DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CoRest and F10E7.11

DIOPT Version :9

Sequence 1:	NP_001188671.1	Gene:	CoRest / 32941	FlyBaseID:	FBgn0261573	Length:	824	Species:	Drosophila melanogaster
Sequence 2:	NP_001379868.1	Gene:	F10E7.11 / 174170	WormBaseID:	WBGene00017352	Length:	239	Species:	Caenorhabditis elegans

Alignment Length:	251	Identity:	56/251 - (22%)
Similarity:	90/251 - (35%)	Gaps:	81/251 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 ESSDDDNSTKRNGKSKAKQSEYEEKIRVGRDYQAVCPPLVPEAERRPEQMNERALLVWS------ 125
            :..|||.:        .....::..|||.........||..||... |...|...::|:
Worm     5 DDDDDDYA--------PPPDPWKRSIRVDPVLFQADVPLFNEATVE-ESAREDDTILWTIDQTNQ 60

  Fly   126 PTKEIPDLKLEEYISVAKE---------KYGYNGEQALGMLFWHKHDLERAVMDLANFTPFP--- 178
            |:.|:.|..|::.:.:.|.         ....:.|.||..|:....|.|:|....    |||
Worm    61 PSDEVIDNYLKDVVGLRKAHDQPCPPAGTESRDDEDALCALYRSNFDTEKAKESF----PFPHIN 121

  Fly   179 -------------DEWTIEDKVLFEQAFQFHGKSFHRIRQM-LPDKSIASLVKYYYSWKKT---- 225
                         ||   .:...||::.:.:||.|..||:: ||.:.:..|::|||.||.|
Worm   122 APFRTVRSDALGFDE---SEAKAFEESLELYGKDFSLIRRLRLPYRKVGELIEYYYQWKLTPGYR 183

  Fly   226 --------------RHRSSAMDRQEKAIKAVVKDGSENG---------SEVGSNEE 258
                          .|.|:|..:|...::      .:||         ||..::||
Worm   184 VWRDAHPQHAPVVQPHLSAAWHQQAAQLE------DQNGQTGFVEASFSEPSTSEE 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CoRest	NP_001188671.1	ELM2	92..144	CDD:279754	14/57 (25%)
		SANT	179..225	CDD:197842	17/46 (37%)
		SANT	180..224	CDD:304392	15/44 (34%)
		SANT	540..582	CDD:238096
F10E7.11	NP_001379868.1	ELM2	22..73	CDD:396160	14/51 (27%)
F10E7.11	NP_001379868.1	SANT_MTA3_like	134..177	CDD:212559	15/45 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810