Protein Alignment CoRest and rcor-1

DIOPT Version :9

• Sequence 1: NP_001188671.1
• Gene: CoRest / 32941
• FlyBaseID: FBgn0261573
• Length: 824
• Species: Drosophila melanogaster
• Sequence 2: NP_490662.1
• Gene: rcor-1 / 171592
• WormBaseID: WBGene00022278
• Length: 564
• Species: Caenorhabditis elegans
• Alignment Length: 540
• Identity: 116/540 - (21%)
• Similarity: 207/540 - (38%)
• Gaps: 95/540 - (17%)

  Fly    67 ESSDDDNSTKRNGKSKAKQSEY-------EEKIRVGRDYQAVCPPLVPEAERRPEQMNERALLVW 124
            |..|::...:.:.:|.|..:.:       :..|.||.:|||:..|...:.|:.|.:..:    :|
 Worm    79 EDEDEEAEAREHHESGAHDTSFSNPLSNVDNLIHVGTEYQAIIQPTAEQLEKEPCRDQQ----IW 139

  Fly   125 SPTKEIPDLKLEEYISVAKEKYGYNGEQALGMLFWHKHDLERAVMDLANFTPFPDEWTIEDKVLF 189
            :...|:.:.:|.||||.|..:|....::||.:|....:|.:.|::.........|:||.|:..||
 Worm   140 AFPDEMNENRLTEYISEATGRYQLPIDRALFILNKQSNDFDAAMVQAMRRKEIHDDWTAEEISLF 204

  Fly   190 EQAFQFHGKSFHRIRQMLPDKSIASLVKYYYSWKKTRHRSSAMDRQEKAIKAVVKDGSENGSEVG 254
            ...|...||.|.:|...:|.:|::|:::|||:.||.::..:.::                   |.
 Worm   205 STCFFHFGKRFKKIHAAMPQRSLSSIIQYYYNTKKVQNYKTMIN-------------------VH 250

  Fly   255 SNEESDNDDKKGHGTNSTINTIDATTTS-TNNSTTNSNTTTPANIIANTINSNHSSSNSGGGGNI 318
            .||....|:     ....:|.::...:. ..|....|:.     :|.|.:.|.|.....     |
 Worm   251 LNETDTYDE-----LFKEVNHLERVPSGYCENCNAKSDL-----LILNRVMSRHECKPC-----I 300

  Fly   319 NNNGEENIQAVGGSNTISNTSNNDMDAEQLSLFA-GNAQIEEMMALGLAADRAIGANGGNNNNNG 382
            .......:........::......:..|.:.::. |..::.| .|.|.|..| :|.......::.
 Worm   301 LYFRLMRVPRPASLRALTKRRQRVLCPEYMKIYVYGYLELME-PANGKAIKR-LGIGKEKEEDDD 363

  Fly   383 EMGGDPGLMRRMVVGGFCKICNVVCHVLHDSPLGRMCKSCHTHWRRTGNRRPISGPEGNA----P 443
            .|..|..|:|: ..|.:     :|...:...|:..  .:|    |.|   |....|...|    .
 Worm   364 IMVVDDCLLRK-PSGPY-----IVEQSIEADPIDE--NTC----RMT---RCFDTPAALALIDNI 413

  Fly   444 RRSTHNCAATADRSKRKPPKGMYINHDDLTALASCGNPSLYLAE--RERKLTALM-------AEI 499
            :|..|.|.....|.|:                ..|...:..|.|  |::...|.|       .||
 Worm   414 KRKHHMCVPLVWRVKQ----------------TKCMEENEILNEEARQQMFRATMTYSRVPKGEI 462

  Fly   500 QKNRQVMEQLDKECETINVDDVLSKPAAANTESAQPRISARWLPDEIQVALLAIREYGKNFPTIA 564
            ...::.|..|....|....:  |...|.....|.:.||:..|.|:|.:.|:.....|..||..||
 Worm   463 ANWKKDMMALKGRFERFTPE--LDTTATNGNRSGKVRINYGWSPEEKKNAIRCFHWYKDNFELIA 525

  Fly   565 KVVATKTEAHVRTFYLNNRR 584
            :::||||...::.||::|.:
 Worm   526 ELMATKTVEQIKKFYMDNEK 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CoRest	NP_001188671.1	ELM2	92..144	CDD:279754	17/51 (33%)
		SANT	179..225	CDD:197842	18/45 (40%)
		SANT	180..224	CDD:304392	16/43 (37%)
		SANT	540..582	CDD:238096	15/41 (37%)
rcor-1	NP_490662.1	Myb_DNA-binding	196..238	CDD:365977	16/41 (39%)
		GATA	275..308	CDD:366024	7/42 (17%)
		Myb_DNA-binding	502..541	CDD:365977	14/38 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160597
Domainoid	1	1.000	86	1.000	Domainoid score	I5150
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	114	1.000	Inparanoid score	I3407
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D287298at33208
OrthoFinder	1	1.000	-	-		FOG0001182
OrthoInspector	1	1.000	-	-		otm14506
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR16089
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3377
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.030