Protein Alignment CoRest and Rcor2

DIOPT Version :9

• Sequence 1: NP_001188671.1
• Gene: CoRest / 32941
• FlyBaseID: FBgn0261573
• Length: 824
• Species: Drosophila melanogaster
• Sequence 2: XP_006526614.1
• Gene: Rcor2 / 104383
• MGIID: 1859854
• Length: 532
• Species: Mus musculus
• Alignment Length: 626
• Identity: 193/626 - (30%)
• Similarity: 275/626 - (43%)
• Gaps: 192/626 - (30%)

  Fly    47 SGNANANEKTTTAVPGAGTPESSDDDNSTKRNGKSKAKQSEYEEKIRVGRDYQAVCPPLVPEAER 111
            :|:...:.......|..|.|.|.||.:..:.:....|.....:..||||.:||||.|...||:..
Mouse    10 AGSGILSRSRAKTAPNGGQPHSEDDSSEEEHSHVLTASPGSTDSMIRVGTNYQAVIPECKPESPA 74

  Fly   112 RPEQMNERALLVWSPTKEIPDLKLEEYISVAKEKYGYNGEQALGMLFWHKHDLERAVMDLANFTP 176
            |......:.:|||||...:.|.||::||::||||:|||.|||||||.|||||:|:::.|||||||
Mouse    75 RYSNKELKGMLVWSPNHCVSDAKLDKYIAMAKEKHGYNIEQALGMLLWHKHDVEKSLADLANFTP 139

  Fly   177 FPDEWTIEDKVLFEQAFQFHGKSFHRIRQMLPDKSIASLVKYYYSWKKTRHRSSAMDRQEKAIKA 241
            ||||||:||||||||||.||||.|.||:||||||.|.|||||||||||||.|:|.||||.:.:.
Mouse   140 FPDEWTVEDKVLFEQAFGFHGKCFQRIQQMLPDKVIPSLVKYYYSWKKTRSRTSVMDRQARRLG- 203

  Fly   242 VVKDGSENGSEVGSNEESDNDD-KKGHGTNSTINTIDATTTSTNNSTTNSNTTTPANIIANTINS 305
                        |..::.|:|: ::|.|..|
Mouse   204 ------------GRKDKEDSDELEEGRGAVS---------------------------------- 222

  Fly   306 NHSSSNSGGGGNINNNGEENIQAVGGSNTISNTSNNDMDAEQLSLFAGNAQIEEMMALGLAADRA 370
                           .||.:.
Mouse   223 ---------------EGEPDT-------------------------------------------- 228

  Fly   371 IGANGGNNNNNGEMGGDPGLMRRMVVGGFCKICNVVCHVLHDSPLGRMCKSCHTHWRRTGNRRPI 435
                           |||   :|              ..|...||               |.||.
Mouse   229 ---------------GDP---KR--------------EPLPSRPL---------------NARPG 246

  Fly   436 SGPEGNAPRRSTHNCAATADRSKRKPPKGMYINHDDLTALASCGNP---SLYLAERERKLTALMA 497
            .|.:.....:..|:..    |::|:||||||::.:.|||::  |:|   :|.|...:.:|.:|..
Mouse   247 PGKKEVQISQYRHHPL----RTRRRPPKGMYLSPEGLTAVS--GSPDLANLTLRGLDSQLISLKR 305

  Fly   498 EIQKNRQVMEQLDKECETINVDDVLSKPAAANTESAQPRISARWLPDEIQVALLAIREYGKNFPT 562
            ::|..:|....|.:..|. .:|.:  :|..|||     :.::||..||..:|:.|||.|||:|..
Mouse   306 QVQSMKQTNSSLRQALEG-GIDPL--RPPEANT-----KFNSRWTTDEQLLAVQAIRRYGKDFGA 362

  Fly   563 IAKVVATKTEAHVRTFYLNNRRRYNLDQIVKEYEAGKSEESGAEEQTEPAVDAAAAGAATASAPS 627
            ||:|:..||...|:||:::.|||:||:::::|:||   |:.||.....|..:|.......|:|..
Mouse   363 IAEVIGNKTLTQVKTFFVSYRRRFNLEEVLQEWEA---EQDGAPAAPVPTEEARRGAPVPATALE 424

  Fly   628 AADSTSAASATADRKQSTENSNNGVETMQESLPKKEDPKKP 668
            ..|.....|.:.                  |:|:...|..|
Mouse   425 EDDEVQITSVST------------------SVPRSVPPAPP 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CoRest	NP_001188671.1	ELM2	92..144	CDD:279754	23/51 (45%)
		SANT	179..225	CDD:197842	38/45 (84%)
		SANT	180..224	CDD:304392	36/43 (84%)
		SANT	540..582	CDD:238096	20/41 (49%)
Rcor2	XP_006526614.1	ELM2	55..107	CDD:366648	23/51 (45%)
		SANT	143..187	CDD:389774	36/43 (84%)
		Myb_DNA-binding	340..383	CDD:365977	20/42 (48%)
		PRK12323	<399..>531	CDD:237057	12/67 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850840
Domainoid	1	1.000	51	1.000	Domainoid score	I11486
eggNOG	1	0.900	-	-		E1_KOG1194
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	299	1.000	Inparanoid score	I2681
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D287298at33208
OrthoFinder	1	1.000	-	-		FOG0001182
OrthoInspector	1	1.000	-	-		otm43348
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR16089
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3377
SonicParanoid	1	1.000	-	-		X1336
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.890