DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CoRest and LOC100535969

DIOPT Version :9

Sequence 1:	NP_001188671.1	Gene:	CoRest / 32941	FlyBaseID:	FBgn0261573	Length:	824	Species:	Drosophila melanogaster
Sequence 2:	XP_009291072.1	Gene:	LOC100535969 / 100535969	-ID:	-	Length:	975	Species:	Danio rerio

Alignment Length:	356	Identity:	92/356 - (25%)
Similarity:	142/356 - (39%)	Gaps:	72/356 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 NGRRSRGP---SPNTHTTGGVTNSASLV----------GSGNNSGHSGNANANEKTTTAVPGAGT 65
            :|:.|||.   .....|...:::.|...          |||..|..||.||........:..||
Zfish   529 DGQESRGAVLFRSQLRTASSMSDDAPYTPPPMLSPARPGSGLFSAVSGRANIQSTPERLLSRAG- 592

  Fly    66 PESSDDDNSTKRNGKSKAKQSEYEEKIRVGRDYQAVCPPLVPEAERRPEQMNERALLVWSPTK-- 128
              ..||...|     .|........:|.:|.::||..|.:  :.:...|:.:..|:|:||.||
Zfish   593 --EMDDCGET-----LKETAINVTPRINIGEEFQAKIPNI--KGQSLTEEDSHNAVLLWSQTKDM 648

  Fly   129 EIPD--LKLEEYISVAKEKY----GYNGEQALGMLFWHKHDLERAVMDL---------ANF-TPF 177
            |.||  .|::..:.:|....    |.|.|..|..||..:.|:...|..|         :|. |.:
Zfish   649 ESPDNQHKVDNLLKMACSSVLPGGGANTEYVLHCLFECRGDIMNTVEKLLLPTLIRHTSNLKTDY 713

  Fly   178 ----PDEWTIEDKVLFEQAFQFHGKSFHRIRQMLPDKSIASLVKYYYSWKKTRHRSSAMDRQEKA 238
                .|.||:::|....:|...|.|.|:.:::|:..||:|..|:|||:|||   |.....|...|
Zfish   714 HYAGSDRWTLQEKRQLNKALLLHHKDFYLVQKMVKTKSVAQCVEYYYTWKK---RLRLCSRVSTA 775

  Fly   239 IKAVVKD-----GSENGSEVGSNEESDNDDKKGHGTNSTINTIDATTTSTNNSTTNSNT-----T 293
            :...|:|     .:.|.||......|.:.|.:    ||:...:   ...||..|...|.     :
Zfish   776 LATPVQDVRGDWATNNHSEPKKESISKSRDSE----NSSAAFV---CEQTNEETWTQNNLRLLCS 833

  Fly   294 TPA----NIIANTINS---NHSSSNSGGGGN 317
            :||    :.:..|:.|   ..|.|||...|:
Zfish   834 SPAEHRPSALTETLGSASVRSSPSNSTTSGD 864

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CoRest	NP_001188671.1	ELM2	92..144	CDD:279754	17/55 (31%)
		SANT	179..225	CDD:197842	18/45 (40%)
		SANT	180..224	CDD:304392	16/43 (37%)
		SANT	540..582	CDD:238096
LOC100535969	XP_009291072.1	zf-C2H2_6	400..421	CDD:290623
		ELM2	612..666	CDD:279754	17/55 (31%)
		SANT	719..765	CDD:197842	19/48 (40%)
		SANT	721..764	CDD:304392	16/42 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810