DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CoRest and mideas

DIOPT Version :9

Sequence 1:	NP_001188671.1	Gene:	CoRest / 32941	FlyBaseID:	FBgn0261573	Length:	824	Species:	Drosophila melanogaster
Sequence 2:	XP_004917289.2	Gene:	mideas / 100495413	XenbaseID:	XB-GENE-1000694	Length:	1080	Species:	Xenopus tropicalis

Alignment Length:	329	Identity:	75/329 - (22%)
Similarity:	129/329 - (39%)	Gaps:	82/329 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 TTTAVPGAGTPESSD----------DDNSTKRNGKSKAKQSEYEEKIRVGRDYQAVCPPLVPEAE 110
            :|..:|...||:||.          ||.........:|.....|.:|.:|..:||..|.|...:.
Frog   649 STQGMPPPVTPKSSTRTLLRSTDSVDDMPPLLTAMGEATPVSIEPRINIGSRFQAEIPDLRHRSS 713

  Fly   111 RRPEQMNERALLVWSPTKEIPDL--KLEEYISVAKEKY----GYNGEQALGMLFWHKHDLERAVM 169
            ...::  ::|.|||.|..|..:.  |:||.::.|....    |.|.|.||..|...|.::..|:.
Frog   714 ATHDE--QKANLVWQPWDESGNNQGKVEELLTAACSSILPGGGTNQELALHYLHETKGNVLAALG 776

  Fly   170 DLANFTP-----FP---------DEWTIEDKVLFEQAFQFHGKSFHRIRQMLPDKSIASLVKYYY 220
            .|....|     .|         |.|::|:|.||.:....:.|.|..:::::..|::|..|::||
Frog   777 QLLLKKPNRSRNHPLCNYHYSGSDRWSVEEKRLFNKGMAIYKKDFLLVQKLIKTKTVAQCVEFYY 841

  Fly   221 SWK---------------------------------KTRHRSSAM--DRQEKAIKAVVKD-GSEN 249
            ::|                                 |:.||...:  .|:|..::...:: .::.
Frog   842 TYKKQVKIGRNGMLIFGDAEPVADEKNPREDSEINIKSSHRIPPVIPPRRELLVERTAEELTADK 906

  Fly   250 GSE-----VGSNEESDNDDKKGHGTNSTINTIDATTTSTNNSTTNSNTTTPANIIANTINSNHSS 309
            |.|     |..||.  .:::|...|.....|::|       |.|.::|....|..:||..::|||
Frog   907 GLEETKIQVNCNEL--EEEEKMPPTTKVTQTLEA-------SETVNDTLILRNQESNTRVADHSS 962

  Fly   310 SNSG 313
            ...|
Frog   963 KARG 966

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CoRest	NP_001188671.1	ELM2	92..144	CDD:279754	16/53 (30%)
		SANT	179..225	CDD:197842	14/78 (18%)
		SANT	180..224	CDD:304392	13/76 (17%)
		SANT	540..582	CDD:238096
mideas	XP_004917289.2	ELM2	695..747	CDD:396160	16/53 (30%)
		BDP1	<797..930	CDD:227448	25/134 (19%)
		SANT	802..845	CDD:419695	12/42 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I11676
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910