Protein Alignment Idh3a and IDH1

DIOPT Version :9

• Sequence 1: NP_001259705.1
• Gene: Idh3a / 32940
• FlyBaseID: FBgn0027291
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_014361.1
• Gene: IDH1 / 855691
• SGDID: S000004982
• Length: 360
• Species: Saccharomyces cerevisiae
• Alignment Length: 336
• Identity: 162/336 - (48%)
• Similarity: 231/336 - (68%)
• Gaps: 9/336 - (2%)

  Fly    46 GTKKVTLIPGDGIGPEISAAVQKIFTAANVPIEWEAVDVTPVRGPDGKFGIPQAAIDSVNTNKIG 110
            |...||||||||:|.||:.:|:.||.|.|:||:||.::   ::..|.|.|:.: |::|:..||||
Yeast    27 GRFTVTLIPGDGVGKEITDSVRTIFEAENIPIDWETIN---IKQTDHKEGVYE-AVESLKRNKIG 87

  Fly   111 LKGPLMTPVGK-GHRSLNLALRKEFNLYANVRPCRSLEGYKTLYDDVDVVTIRENTEGEYSGIEH 174
            |||...||..: ||.|||:||||:.::||||...:||:|.||...|:|::.||||||||:||:||
Yeast    88 LKGLWHTPADQTGHGSLNVALRKQLDIYANVALFKSLKGVKTRIPDIDLIVIRENTEGEFSGLEH 152

  Fly   175 EIVDGVVQSIKLITEEASKRVAEYAFQYAKNNNRKKVTVVHKANIMRMSDGLFLRCVRDMAQK-F 238
            |.|.|||:|:|::|...::|:|.:||.:||..|||.||.|||||||::.||||...:.::.|| :
Yeast   153 ESVPGVVESLKVMTRPKTERIARFAFDFAKKYNRKSVTAVHKANIMKLGDGLFRNIITEIGQKEY 217

  Fly   239 PEIQFEEKYLDTVCLNMVQNPGKYDVLVMPNLYGDILSDMCAGLVGGLGLTPSGNMGLNGALFE- 302
            |:|......:|...:..|..|.::||||.|::||.||.::.|.|:||.||....|.|.:.|:||
Yeast   218 PDIDVSSIIVDNASMQAVAKPHQFDVLVTPSMYGTILGNIGAALIGGPGLVAGANFGRDYAVFEP 282

  Fly   303 -SVHGTAPDIAGKDLANPTALLLSAVMMLRHMELNTYADKIERAAFETIKEGKYLTGDLGGRAKC 366
             |.| ...||.|:::|||||::||:.:||.|:.||.||.:|.:|..|||.|||:.|.|:||.:..
Yeast   283 GSRH-VGLDIKGQNVANPTAMILSSTLMLNHLGLNEYATRISKAVHETIAEGKHTTRDIGGSSST 346

  Fly   367 SEFTNEICAKL 377
            ::|||||..||
Yeast   347 TDFTNEIINKL 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Idh3a	NP_001259705.1	Iso_dh	46..377	CDD:294303	160/334 (48%)
IDH1	NP_014361.1	mito_nad_idh	26..357	CDD:272942	160/334 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0473
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53770
OrthoFinder	1	1.000	-	-		FOG0000244
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X402
TreeFam	0	0.000	Not matched by this tool.
	5	4.820