Protein Alignment Idh3a and LYS12

DIOPT Version :9

• Sequence 1: NP_001259705.1
• Gene: Idh3a / 32940
• FlyBaseID: FBgn0027291
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_012172.1
• Gene: LYS12 / 854714
• SGDID: S000001356
• Length: 371
• Species: Saccharomyces cerevisiae
• Alignment Length: 366
• Identity: 130/366 - (35%)
• Similarity: 201/366 - (54%)
• Gaps: 33/366 - (9%)

  Fly    35 ATPAASRSYSSGTKKVTLIPGDGIGPEISAAVQKIFTAANVP--IEWEAVDVTPVRG-----PDG 92
            |:.||.:|.:.|     ||||||||.|:..|.:::....|..  :.:..:|:  ..|     ..|
Yeast    16 ASNAARKSLTIG-----LIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDL--YAGFQTFQETG 73

  Fly    93 KFGIPQAAIDSVNTNKIG-LKGPLMTPVGK--GHRSLNLALRKEFNLYANVRPCRSLEGYKTLYD 154
            | .:|...:..:.....| |.|.:.:|..|  |:.|..:|||:|..|:|||||.:|:||.|.  .
Yeast    74 K-ALPDETVKVLKEQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFANVRPVKSVEGEKG--K 135

  Fly   155 DVDVVTIRENTEGEYSGIEHEIVD-----GVVQSIKLITEEASKRVAEYAFQYA----KNNNRKK 210
            .:|:|.:|||||..|..||...:|     .|..:.|.|:|.|::|:|..|...|    :...:..
Yeast   136 PIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALKRLQTRGQAT 200

  Fly   211 VTVVHKANIMRMSDGLFLRCVRDMAQ----KFPEIQFEEKYLDTVCLNMVQNPGKYDVLVMPNLY 271
            :||.||:|::..|||||....:::.:    |:.:|::.|:.:|::...:.:.|..:||:|.||||
Yeast   201 LTVTHKSNVLSQSDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFREPQCFDVIVAPNLY 265

  Fly   272 GDILSDMCAGLVGGLGLTPSGNMGLNGALFESVHGTAPDIAGKDLANPTALLLSAVMMLRHMELN 336
            ||||||..|.|||.||:.||.|:|....:.|..||:|||||||.:|||.|.:.|..:||..:..|
Yeast   266 GDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHGSAPDIAGKGIANPIATIRSTALMLEFLGHN 330

  Fly   337 TYADKIERAAFETIKEGKYLTGDLGGRAKCSEFTNEICAKL 377
            ..|..|.:|....::||...|.||||:|...:..:::.::|
Yeast   331 EAAQDIYKAVDANLREGSIKTPDLGGKASTQQVVDDVLSRL 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Idh3a	NP_001259705.1	Iso_dh	46..377	CDD:294303	125/353 (35%)
LYS12	NP_012172.1	LeuB	21..371	CDD:223549	126/359 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0473
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S361
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000244
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100541
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X402
TreeFam	1	0.960	-	-
	7	6.620