Protein Alignment Idh3a and LEU2

DIOPT Version :9

• Sequence 1: NP_001259705.1
• Gene: Idh3a / 32940
• FlyBaseID: FBgn0027291
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_009911.2
• Gene: LEU2 / 850342
• SGDID: S000000523
• Length: 364
• Species: Saccharomyces cerevisiae
• Alignment Length: 364
• Identity: 115/364 - (31%)
• Similarity: 177/364 - (48%)
• Gaps: 49/364 - (13%)

  Fly    45 SGTKKVTLIPGDGIGPEISAAVQKIFTA-----ANVPIEWE-------AVDVTPVRGPDGKFGIP 97
            |..||:.::|||.:|.||:|...|:..|     :||..::|       |:|.|.|..||......
Yeast     2 SAPKKIVVLPGDHVGQEITAEAIKVLKAISDVRSNVKFDFENHLIGGAAIDATGVPLPDEALEAS 66

  Fly    98 QAAIDSVNTNKIGLKGPLMTPVGKG----HRSLNLALRKEFNLYANVRPCR-------SLEGYKT 151
            :.| |:|....:|  ||..   |.|    .:.| |.:|||..||||:|||.       .|...|.
Yeast    67 KKA-DAVLLGAVG--GPKW---GTGSVRPEQGL-LKIRKELQLYANLRPCNFASDSLLDLSPIKP 124

  Fly   152 LY-DDVDVVTIRENTEGEYSGIEHE-IVDGVVQSIKLITEEASKRVAEY-AFQYAKNNNRKKVTV 213
            .: ...|.|.:||...|.|.|...| ..|||....:..|....:|:... ||...::.....:..
Yeast   125 QFAKGTDFVVVRELVGGIYFGKRKEDDGDGVAWDSEQYTVPEVQRITRMAAFMALQHEPPLPIWS 189

  Fly   214 VHKANIMRMSDGLFLRCVRD-MAQKFPEIQFEEKYLDTVCLNMVQNPGKYD-VLVMPNLYGDILS 276
            :.|||:: .|..|:.:.|.: :..:||.::.:.:.:|:..:.:|:||...: :::..|::|||:|
Yeast   190 LDKANVL-ASSRLWRKTVEETIKNEFPTLKVQHQLIDSAAMILVKNPTHLNGIIITSNMFGDIIS 253

  Fly   277 DMCAGLVGGLGLTPSGNMG----LNGA--LFESVHGTAPDIAGKDLANPTALLLSAVMMLR-HME 334
            |..:.:.|.|||.||.::.    .|.|  |:|..||:|||:. |:..||.|.:|||.|||: .:.
Yeast   254 DEASVIPGSLGLLPSASLASLPDKNTAFGLYEPCHGSAPDLP-KNKVNPIATILSAAMMLKLSLN 317

  Fly   335 LNTYADKIERAAFETIKEGKYLTGDLGGRAKCSEFTNEI 373
            |......||.|..:.:..| ..||||||    |..|.|:
Yeast   318 LPEEGKAIEDAVKKVLDAG-IRTGDLGG----SNSTTEV 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Idh3a	NP_001259705.1	Iso_dh	46..377	CDD:294303	114/363 (31%)
LEU2	NP_009911.2	leuB	6..359	CDD:272939	113/360 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0473
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S361
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.720