DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idh3a and IDH-VI

DIOPT Version :9

Sequence 1:	NP_001259705.1	Gene:	Idh3a / 32940	FlyBaseID:	FBgn0027291	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	NP_850549.1	Gene:	IDH-VI / 820139	AraportID:	AT3G09810	Length:	374	Species:	Arabidopsis thaliana

Alignment Length:	380	Identity:	217/380 - (57%)
Similarity:	277/380 - (72%)	Gaps:	15/380 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAARFIQKILNQ-LGLIAARDAPAVTATPAVSQVNATPAASRSYSSGTK-KVTLIPGDGIGPEIS 63
            :|.|.|....:| ||..::...|.::.:.|.            :||.|. |.||.|||||||||:
plant     7 LARRLIGNGSSQILGTSSSSSGPFISVSRAF------------FSSSTPIKATLFPGDGIGPEIA 59

  Fly    64 AAVQKIFTAANVPIEWEAVDVTPVRGPDGKFGIPQAAIDSVNTNKIGLKGPLMTPVGKGHRSLNL 128
            .:|:::||||:|.|:|:...|.....|.....:....:.||..||:|||||:.||:|||||||||
plant    60 ESVKQVFTAADVVIDWDEQFVGTEVDPRTNSFLTWDNLQSVLKNKVGLKGPMATPIGKGHRSLNL 124

  Fly   129 ALRKEFNLYANVRPCRSLEGYKTLYDDVDVVTIRENTEGEYSGIEHEIVDGVVQSIKLITEEASK 193
            .||||.|||||||||.||.||||.|||||::||||||||||||:||::|.|||:|:|:||.:||.
plant   125 TLRKELNLYANVRPCYSLPGYKTRYDDVDLITIRENTEGEYSGLEHQVVKGVVESLKIITRKASM 189

  Fly   194 RVAEYAFQYAKNNNRKKVTVVHKANIMRMSDGLFLRCVRDMAQKFPEIQFEEKYLDTVCLNMVQN 258
            |||||||.|||.:.||||:.:||||||:.:|||||:|..::|.|:|||.:|:..:|..|:.:|:|
plant   190 RVAEYAFLYAKTHGRKKVSAIHKANIMQKTDGLFLQCCDEVAAKYPEIYYEKVVIDNCCMMLVKN 254

  Fly   259 PGKYDVLVMPNLYGDILSDMCAGLVGGLGLTPSGNMGLNG-ALFESVHGTAPDIAGKDLANPTAL 322
            |..:||||||||||||:||:|||||||||||||.|:|.:| ||.|:|||:||||||.:|||||||
plant   255 PALFDVLVMPNLYGDIISDLCAGLVGGLGLTPSMNIGEDGIALAEAVHGSAPDIAGMNLANPTAL 319

  Fly   323 LLSAVMMLRHMELNTYADKIERAAFETIKEGKYLTGDLGGRAKCSEFTNEICAKL 377
            |||.||||||::||..|::|..|...||.||||.|.||||.:..::||..||..|
plant   320 LLSGVMMLRHLKLNKQAEQIHSAIINTIAEGKYRTADLGGSSTTTDFTKAICDHL 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idh3a	NP_001259705.1	Iso_dh	46..377	CDD:294303	206/332 (62%)
IDH-VI	NP_850549.1	PLN00118	3..374	CDD:215062	216/378 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	426	1.000	Domainoid score	I113
eggNOG	1	0.900	-	-		E1_COG0473
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4037
Inparanoid	1	1.050	434	1.000	Inparanoid score	I415
OMA	1	1.010	-	-		QHG53770
OrthoDB	1	1.010	-	-		D868374at2759
OrthoFinder	1	1.000	-	-		FOG0000244
OrthoInspector	1	1.000	-	-		mtm1151
orthoMCL	1	0.900	-	-		OOG6_100541
Panther	1	1.100	-	-	O	PTHR11835
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X402
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840