Protein Alignment Idh3a and idh3a

DIOPT Version :10

• Sequence 1: NP_001259705.1
• Gene: Idh3a / 32940
• FlyBaseID: FBgn0027291
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_989352.1
• Gene: idh3a / 394979
• XenbaseID: XB-GENE-943186
• Length: 366
• Species: Xenopus tropicalis
• Alignment Length: 363
• Identity: 247/363 - (68%)
• Similarity: 293/363 - (80%)
• Gaps: 10/363 - (2%)

  Fly    16 IAARDAPAVTATPAVSQVNATPAASRSYSSGTKKVTLIPGDGIGPEISAAVQKIFTAANVPIEWE 80
            :.:|.|.|:|         |....:|..|:..:.||||||||||||||.||.|||..|..|::||
 Frog     9 LISRVAGALT---------APEYGARQLSNHVQTVTLIPGDGIGPEISTAVMKIFETAKAPVQWE 64

  Fly    81 AVDVTPVRGPDGKFGIPQAAIDSVNTNKIGLKGPLMTPVGKGHRSLNLALRKEFNLYANVRPCRS 145
            ..:||.::||.||:.||..|.:|::.||:||||||.||:..||.|:||.|||.|:||||||||.|
 Frog    65 ERNVTAIKGPGGKWMIPPEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVS 129

  Fly   146 LEGYKTLYDDVDVVTIRENTEGEYSGIEHEIVDGVVQSIKLITEEASKRVAEYAFQYAKNNNRKK 210
            :|||:|.|.|||:||||||||||||||||.|||||||||||||||||.|:|::||:||:||.|..
 Frog   130 IEGYRTPYTDVDLVTIRENTEGEYSGIEHVIVDGVVQSIKLITEEASHRIAQFAFEYARNNQRST 194

  Fly   211 VTVVHKANIMRMSDGLFLRCVRDMAQKFPEIQFEEKYLDTVCLNMVQNPGKYDVLVMPNLYGDIL 275
            ||.|||||||||||||||:..|::|:.|.:|:|.|.|||||||||||:|.::|||||||||||||
 Frog   195 VTAVHKANIMRMSDGLFLKKCREVAENFKDIKFNEMYLDTVCLNMVQDPTQFDVLVMPNLYGDIL 259

  Fly   276 SDMCAGLVGGLGLTPSGNMGLNG-ALFESVHGTAPDIAGKDLANPTALLLSAVMMLRHMELNTYA 339
            ||:||||:||||:|||||:|.|| |:|||||||||||||||||||||||||||||||||.|:.:|
 Frog   260 SDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDLANPTALLLSAVMMLRHMGLHEHA 324

  Fly   340 DKIERAAFETIKEGKYLTGDLGGRAKCSEFTNEICAKL 377
            .|||.|.|||||.||.||.||||.:||||||||||.::
 Frog   325 RKIENACFETIKSGKALTKDLGGNSKCSEFTNEICRRI 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Idh3a	NP_001259705.1	Iso_dh	46..377	CDD:444908	240/331 (73%)
idh3a	NP_989352.1	Iso_dh	31..362	CDD:444908	240/330 (73%)