Protein Alignment Idh3a and idh1

DIOPT Version :9

• Sequence 1: NP_001259705.1
• Gene: Idh3a / 32940
• FlyBaseID: FBgn0027291
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_594397.1
• Gene: idh1 / 2541894
• PomBaseID: SPAC11G7.03
• Length: 356
• Species: Schizosaccharomyces pombe
• Alignment Length: 335
• Identity: 168/335 - (50%)
• Similarity: 222/335 - (66%)
• Gaps: 3/335 - (0%)

  Fly    46 GTKKVTLIPGDGIGPEISAAVQKIFTAANVPIEWEAVDVTPVRGPDGKFG-IPQAAIDSVNTNKI 109
            |...||||||||||.|.|.||.:||..||||||:|.:|||.:...:...| ....||.|:..||:
pombe    19 GKYTVTLIPGDGIGRETSNAVTEIFKTANVPIEFEEIDVTGMEKNNKSSGDALHEAIQSLKRNKV 83

  Fly   110 GLKGPLMTPVGK-GHRSLNLALRKEFNLYANVRPCRSLEGYKTLYDDVDVVTIRENTEGEYSGIE 173
            ||||.|.||..| ||.|.|:|||||.::||::...:::.|:||.:|:||...|||||||||||:|
pombe    84 GLKGILFTPFEKGGHTSFNVALRKELDIYASLVLIKNIPGFKTRHDNVDFAIIRENTEGEYSGLE 148

  Fly   174 HEIVDGVVQSIKLITEEASKRVAEYAFQYAKNNNRKKVTVVHKANIMRMSDGLFLRCVRDMAQKF 238
            |:.|.|||:|:|:|||..|||:|::||.:|..|.||.||.:||||||:::||||.|...|:|..:
pombe   149 HQSVPGVVESLKIITEYKSKRIAQFAFDFALQNGRKSVTCIHKANIMKLADGLFRRTFYDVANGY 213

  Fly   239 PEIQFEEKYLDTVCLNMVQNPGKYDVLVMPNLYGDILSDMCAGLVGGLGLTPSGNMGLNGALFE- 302
            ..|..::..:|...:..|..|.::||||||||||.|||::.:.||||.|:.|..|.|.:.||||
pombe   214 DAITPKDLIVDNASMQAVSRPQQFDVLVMPNLYGSILSNIGSALVGGPGVIPGANFGRDYALFEP 278

  Fly   303 SVHGTAPDIAGKDLANPTALLLSAVMMLRHMELNTYADKIERAAFETIKEGKYLTGDLGGRAKCS 367
            ........|.|:..|||||.:|||.:||||:.|..|||.|..|.:..|:|||.||.||||.|...
pombe   279 GCRHVGLSITGRGEANPTAAILSACLMLRHLGLKDYADLINAATYSVIEEGKTLTKDLGGSASTG 343

  Fly   368 EFTNEICAKL 377
            :||:.|..::
pombe   344 DFTHAILERM 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Idh3a	NP_001259705.1	Iso_dh	46..377	CDD:294303	168/333 (50%)
idh1	NP_594397.1	mito_nad_idh	18..353	CDD:272942	168/333 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0473
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53770
OrthoFinder	1	1.000	-	-		FOG0000244
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820