Protein Alignment Idh3a and idhg-1

DIOPT Version :10

• Sequence 1: NP_001259705.1
• Gene: Idh3a / 32940
• FlyBaseID: FBgn0027291
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_497927.2
• Gene: idhg-1 / 175598
• WormBaseID: WBGene00009440
• Length: 396
• Species: Caenorhabditis elegans
• Alignment Length: 351
• Identity: 147/351 - (41%)
• Similarity: 219/351 - (62%)
• Gaps: 13/351 - (3%)

  Fly    30 VSQVNATPAASRSYSSGTKKVTLIPGDGIGPEISAAVQKIFTAANVPIEWEAVDVTPVRGPDGKF 94
            |.|.|.|..|.   ..|...||::||||||||:...|::|.:|...|:::|.|::|...  |...
 Worm    37 VLQTNTTKLAR---YGGRHNVTVLPGDGIGPEMLHHVERILSAVQAPVDFEVVNLTSKE--DASE 96

  Fly    95 GIPQAAIDSVNTNKIGLKGPLMTPV-GKGHRSLNLALRKEFNLYANVRPCRSLEGYKTLYDDVDV 158
            .:.: ||.::..|.:.|||.:.|.. .....|.||.||::.||||||..|.::....:.:..:|:
 Worm    97 DLAE-AITAIKRNGVALKGNIETKFDNPSFVSRNLELRRQLNLYANVLHCSTIPTVPSRHTGIDM 160

  Fly   159 VTIRENTEGEYSGIEHEIVDG----VVQSIKLITEEASKRVAEYAFQYAKNNNRKKVTVVHKANI 219
            |.|||||||||||.|||.|:.    ||:|:|::|.|.|:::..:|||:||...|||||.||||||
 Worm   161 VIIRENTEGEYSGNEHEAVNAPHPRVVESLKVVTREKSEQITRFAFQFAKKYGRKKVTAVHKANI 225

  Fly   220 MRMSDGLFLRCVRDMAQ-KFPEIQFEEKYLDTVCLNMVQNPGKYDVLVMPNLYGDILSDMCAGLV 283
            .::.|||||:...|:|: ::|:|:|....:|...:.:|..|.::||::||||||:|:|::..|||
 Worm   226 QKLGDGLFLKVATDIAKAEYPDIEFNAMIVDNASMQLVSRPQQFDVMLMPNLYGNIISNIACGLV 290

  Fly   284 GGLGLTPSGNMGLNGALFES-VHGTAPDIAGKDLANPTALLLSAVMMLRHMELNTYADKIERAAF 347
            ||.||....|:|.:.|:||: ...|...:||||||||||.:.:||.|||.:.|.::||.|..:.|
 Worm   291 GGPGLVSGMNIGEDYAVFETGTRNTGTTLAGKDLANPTAFIRAAVDMLRFLGLQSHADMISDSLF 355

  Fly   348 ETIKEGKYLTGDLGGRAKCSEFTNEI 373
            .|:.:.:..|.|:||.:|.||....:
 Worm   356 RTLVDKRIHTADIGGTSKSSELVQSV 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Idh3a	NP_001259705.1	Iso_dh	46..377	CDD:444908	142/335 (42%)
idhg-1	NP_497927.2	Iso_dh	49..383	CDD:444908	142/336 (42%)