Protein Alignment Idh3a and idha-1

DIOPT Version :9

• Sequence 1: NP_001259705.1
• Gene: Idh3a / 32940
• FlyBaseID: FBgn0027291
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_492330.2
• Gene: idha-1 / 172655
• WormBaseID: WBGene00009664
• Length: 358
• Species: Caenorhabditis elegans
• Alignment Length: 349
• Identity: 246/349 - (70%)
• Similarity: 292/349 - (83%)
• Gaps: 1/349 - (0%)

  Fly    30 VSQVNATPAASRSYSSG-TKKVTLIPGDGIGPEISAAVQKIFTAANVPIEWEAVDVTPVRGPDGK 93
            :.:.::|...|..|||| .::|||||||||||||||:|||||.||:.||.|:.||||||:|.||.
 Worm     6 IKKASSTVGQSIRYSSGDVRRVTLIPGDGIGPEISASVQKIFEAADAPIAWDPVDVTPVKGRDGV 70

  Fly    94 FGIPQAAIDSVNTNKIGLKGPLMTPVGKGHRSLNLALRKEFNLYANVRPCRSLEGYKTLYDDVDV 158
            |.||...|:.::.||:||||||.||:||||||||||:||||:|||||||||||||:|||||:|||
 Worm    71 FRIPSRCIELMHANKVGLKGPLETPIGKGHRSLNLAVRKEFSLYANVRPCRSLEGHKTLYDNVDV 135

  Fly   159 VTIRENTEGEYSGIEHEIVDGVVQSIKLITEEASKRVAEYAFQYAKNNNRKKVTVVHKANIMRMS 223
            |||||||||||||||||||.|||||||||||.||:.||.:||:||:.|.||.||.||||||||.|
 Worm   136 VTIRENTEGEYSGIEHEIVPGVVQSIKLITETASRNVASFAFEYARQNGRKVVTAVHKANIMRQS 200

  Fly   224 DGLFLRCVRDMAQKFPEIQFEEKYLDTVCLNMVQNPGKYDVLVMPNLYGDILSDMCAGLVGGLGL 288
            |||||...|:.|..:|:|:|:|.|||||||||||:|.:||||||||||||||||:|||||||||:
 Worm   201 DGLFLSICREQAALYPDIKFKEAYLDTVCLNMVQDPSQYDVLVMPNLYGDILSDLCAGLVGGLGV 265

  Fly   289 TPSGNMGLNGALFESVHGTAPDIAGKDLANPTALLLSAVMMLRHMELNTYADKIERAAFETIKEG 353
            |||||:|...|:|||||||||||||:|.|||||||||||||||:|.|..:|.:||:|.|:.|.:|
 Worm   266 TPSGNIGKGAAVFESVHGTAPDIAGQDKANPTALLLSAVMMLRYMNLPQHAARIEKAVFDAIADG 330

  Fly   354 KYLTGDLGGRAKCSEFTNEICAKL 377
            :..||||||...||.||.::||::
 Worm   331 RAKTGDLGGTGTCSSFTADVCARV 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Idh3a	NP_001259705.1	Iso_dh	46..377	CDD:294303	241/331 (73%)
idha-1	NP_492330.2	Iso_dh	22..354	CDD:294303	241/331 (73%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167073
Domainoid	1	1.000	486	1.000	Domainoid score	I190
eggNOG	1	0.900	-	-		E1_COG0473
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4037
Inparanoid	1	1.050	501	1.000	Inparanoid score	I749
Isobase	1	0.950	-	0	Normalized mean entropy	S361
OMA	1	1.010	-	-		QHG53770
OrthoDB	1	1.010	-	-		D325037at33208
OrthoFinder	1	1.000	-	-		FOG0000244
OrthoInspector	1	1.000	-	-		oto20185
orthoMCL	1	0.900	-	-		OOG6_100541
Panther	1	1.100	-	-	LDO	PTHR11835
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R586
SonicParanoid	1	1.000	-	-		X402
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	16	15.790