Protein Alignment Idh3a and idhg-2

DIOPT Version :10

• Sequence 1: NP_001259705.1
• Gene: Idh3a / 32940
• FlyBaseID: FBgn0027291
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_491989.1
• Gene: idhg-2 / 172430
• WormBaseID: WBGene00016266
• Length: 373
• Species: Caenorhabditis elegans
• Alignment Length: 369
• Identity: 147/369 - (39%)
• Similarity: 224/369 - (60%)
• Gaps: 18/369 - (4%)

  Fly     9 ILNQLGLIAARDAPAVTATPAVSQVNATPAASRSYSSGTKKVTLIPGDGIGPEISAAVQKIFTAA 73
            :.::|.:.|.|.|.:...|..:.. :..|.|.   ..|...|..:||||||||:.|.::.||:..
 Worm     1 MFSKLPIQAVRGAASAIRTHQIPG-HRLPLAK---YGGRHTVCALPGDGIGPEMIAHIRNIFSFC 61

  Fly    74 NVPIEWEAVDVTPVRGPDGKFGIPQAAIDSVNTNKIGLKGPLMTPVGKGH-----RSLNLALRKE 133
            :.|:.:|.|.|:... .||..   .||:.::..|.:.:||.:.|.    |     .|.|:.||.:
 Worm    62 HAPVNFEEVQVSSSL-LDGDM---DAAMLAIERNGVAIKGNIETK----HDDPQFNSRNVELRTK 118

  Fly   134 FNLYANVRPCRSLEGYKTLYDDVDVVTIRENTEGEYSGIEHEIVDGVVQSIKLITEEASKRVAEY 198
            .:||||:..|.::....|.:..:|:|.|||||||||||:|||.|.|:|:|||::|.|..:|::..
 Worm   119 LDLYANILHCVTIPTVPTRHSGIDIVLIRENTEGEYSGLEHEAVPGIVESIKIVTREKIERISRM 183

  Fly   199 AFQYAKNNNRKKVTVVHKANIMRMSDGLFLRCVRDMAQKFPEIQFEEKYLDTVCLNMVQNPGKYD 263
            ||:|||.|.|||||.||||||.::.|||||:.||||::.:.:|:||...:|...:.:|..|.::|
 Worm   184 AFEYAKANGRKKVTAVHKANIQKLGDGLFLKVVRDMSEDYKDIKFEAMIVDNASMQLVSKPQQFD 248

  Fly   264 VLVMPNLYGDILSDMCAGLVGGLGLTPSGNMGLNGALFES-VHGTAPDIAGKDLANPTALLLSAV 327
            |:|||||||:|:|::..|||||.||....|:|...|:||: ...|...:||||:|||||.:.::|
 Worm   249 VMVMPNLYGNIISNIACGLVGGPGLVSGMNLGDKYAVFETGTRNTGTSLAGKDIANPTAFIRASV 313

  Fly   328 MMLRHMELNTYADKIERAAFETIKEGKYLTGDLGGRAKCSEFTN 371
            .|||::..:.:|:.|..|.::.:.|.:..|.|:||....|:..|
 Worm   314 DMLRYLGCHYHANIISDALWKALVEQRIHTADIGGNNSASDVIN 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Idh3a	NP_001259705.1	Iso_dh	46..377	CDD:444908	140/332 (42%)
idhg-2	NP_491989.1	Iso_dh	33..363	CDD:444908	140/333 (42%)