Protein Alignment Idh3a and Idh3b

DIOPT Version :9

• Sequence 1: NP_001259705.1
• Gene: Idh3a / 32940
• FlyBaseID: FBgn0027291
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_570954.1
• Gene: Idh3b / 170718
• MGIID: 2158650
• Length: 384
• Species: Mus musculus
• Alignment Length: 376
• Identity: 155/376 - (41%)
• Similarity: 241/376 - (64%)
• Gaps: 23/376 - (6%)

  Fly    15 LIAARDAPA----VTATPAVSQVNATPAASRSYS-----SGTKKVTLIPGDGIGPEISAAVQKIF 70
            ::|||::.|    .|:|        ..|||:|.:     .|...||::||||:|||:..||:::|
Mouse    14 VLAARNSGAWRGLGTST--------AHAASQSQAQDVRVEGAFPVTMLPGDGVGPELMHAVKEVF 70

  Fly    71 TAANVPIEWEAVDVTPVRGPDGKFGIPQAAIDSVNTNKIGLKGPLMTPVG-KGH-RSLNLALRKE 133
            .||.||:|::...::.|:....:..:.| .:.|:..||:.:.|.:.||:. ||. .|.::.||::
Mouse    71 KAAAVPVEFKEHHLSEVQNMASEEKLEQ-VLSSMKENKVAIIGKIYTPMEYKGELASYDMQLRRK 134

  Fly   134 FNLYANVRPCRSLEGYKTLYDDVDVVTIRENTEGEYSGIEHEIVDGVVQSIKLITEEASKRVAEY 198
            .:|:|||...:||.||||.::::|:|.|||.||||||.:|||...||::.:|::|...|:|:|::
Mouse   135 LDLFANVVHVKSLPGYKTRHNNLDLVIIREQTEGEYSSLEHESAKGVIECLKIVTRTKSQRIAKF 199

  Fly   199 AFQYAKNNNRKKVTVVHKANIMRMSDGLFLRCVRDMAQKFPEIQFEEKYLDTVCLNMVQNPGKYD 263
            ||.||....|.|||.|||||||::.|||||:|..::|:.:|:|:||...:|..|:.:||||.::|
Mouse   200 AFDYATKKGRSKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQNPYQFD 264

  Fly   264 VLVMPNLYGDILSDMCAGLVGGLGLTPSGNMGLNGALFE--SVHGTAPDIAGKDLANPTALLLSA 326
            |||||||||:|:.::.||||||.|:.|..:.....|:||  :.|..|..: |:::|||||:||||
Mouse   265 VLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAV-GRNIANPTAMLLSA 328

  Fly   327 VMMLRHMELNTYADKIERAAFETIKEGKYLTGDLGGRAKCSEFTNEICAKL 377
            ..||||:.|..::..|..|..:.||.||..|.|:||.:..::|...:...|
Mouse   329 TNMLRHLNLEYHSSMIADAVKKVIKAGKVRTRDMGGYSTTTDFIKSVIGHL 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Idh3a	NP_001259705.1	Iso_dh	46..377	CDD:294303	144/334 (43%)
Idh3b	NP_570954.1	Iso_dh	46..379	CDD:351095	144/334 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0473
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53770
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000244
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820