DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pfrx and YNL108C

DIOPT Version :9

Sequence 1:	NP_477451.1	Gene:	Pfrx / 32938	FlyBaseID:	FBgn0027621	Length:	716	Species:	Drosophila melanogaster
Sequence 2:	NP_014291.1	Gene:	YNL108C / 855615	SGDID:	S000005052	Length:	270	Species:	Saccharomyces cerevisiae

Alignment Length:	194	Identity:	46/194 - (23%)
Similarity:	79/194 - (40%)	Gaps:	45/194 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   468 IYLTRHGESEYNLSGL-----------IGGDSNLSARGHQYANALSTFIAQQQIDGLRVWTSWMK 521
            ||:.|||   |..:.|           |..|..||..|.:.|:.|:.:|::..:....:::|...
Yeast     6 IYIARHG---YRSNWLPKGPYPPPPTGIDNDVPLSEHGVEQAHELANYISKLDVKPEMIFSSPFY 67

  Fly   522 RAIQTVADVKAPQERWKALNEIDAGHCEEMTYEQIKEKFPEEFKARDVNKFAYRYP--------- 577
            |.::|   .|...|..|....:|.|..|  .|:..:...||......::||   :|
Yeast    68 RCLET---SKPTVEALKIPLYVDRGVGE--WYKPDRPIIPEPATHEVMSKF---FPSMISPDWEP 124

  Fly   578 ------RGESYEDLVARLE---PVIME-LERQ----GNVLVVSHQAVLRCLFAYFLDKSADELP 627
                  :||:.||:..|..   ||.:: :||:    ..:::|:|.|....|....|..|:.:.|
Yeast   125 SIIPSNKGETEEDIFERCHKFWPVFIDRVERKFPNVKTIMIVTHAATKSALGMNLLKFSSAKEP 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pfrx	NP_477451.1	6PF2K	254..465	CDD:279872
		AAA_33	256..412	CDD:290396
		His_Phos_1	468..651	CDD:278716	46/194 (24%)
YNL108C	NP_014291.1	PhoE	5..227	CDD:223483	46/194 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0406
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810