Protein Alignment Pfrx and UBASH3B

DIOPT Version :9

• Sequence 1: NP_477451.1
• Gene: Pfrx / 32938
• FlyBaseID: FBgn0027621
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: XP_005271769.1
• Gene: UBASH3B / 84959
• HGNCID: 29884
• Length: 677
• Species: Homo sapiens
• Alignment Length: 712
• Identity: 126/712 - (17%)
• Similarity: 216/712 - (30%)
• Gaps: 300/712 - (42%)

  Fly    56 ASSEAQRTKANPNQILSASNSSSIDEQDEDQVGTLPLPLLSINRRTPTLLPRPVPPSSTRFTSSY 120
            ||:..:..:|..:.:.|......:|:         |||      |...|..||..|.:.:.:..:
Human    87 ASTGGRSVQAACDWLFSHVGDPFLDD---------PLP------REYVLYLRPTGPLAQKLSDFW 136

  Fly   121 NDDLCTC-SNCAYSSFSSSSSSASSTSSSSTSATAAGTALASAAASAVAKKLARSVTATSIMDMP 184
            ......| .|.|::.|...:.........| ...|.|.||.:..:....|..|         .:|
Human   137 QQSKQICGKNKAHNIFPHITLCQFFMCEDS-KVDALGEALQTTVSRWKCKFSA---------PLP 191

  Fly   185 ---YNTSP--SLRVRTTSLNQLKK-TADLAIE----NELHVCPSVMSEELRKLLPPTSETVMTKP 239
               |.:|.  .|.|:..|...||| .||.|.|    .|:||
Human   192 LELYTSSNFIGLFVKEDSAEVLKKFAADFAAEAASKTEVHV------------------------ 232

  Fly   240 FPIRGERTIADCTTPHVIAMVGLPARGKTFISKKLARYLNWIGISTRVFNLGEYRRHATTAYKSH 304
                         .||               .|:|                     |.|.||
Human   233 -------------EPH---------------KKQL---------------------HVTLAY--- 245

  Fly   305 EFFRADNEEAMAIRNRCANQALHDSCDWLLSGQGSIAVFDATNSTRDRRQLIHDIVVKQHGFRLF 369
             .|:|.:  ...:.....|..:...|||:           ||..:||.|...|:.:
Human   246 -HFQASH--LPTLEKLAQNIDVKLGCDWV-----------ATIFSRDIRFANHETL--------- 287

  Fly   370 FVESICDDPQII----EQNILEVKVSSPDYLNMN---------------------TELVVRDFLQ 409
                     |:|    .||..|:::...|::.|:                     :.|:..:::.
Human   288 ---------QVIYPYTPQNDDELELVPGDFIFMSPMEQTSTSEGWIYGTSLTTGCSGLLPENYIT 343

  Fly   410 RIEH-----YEERYQPIDEVTESHLSFMKVYNAGKKVV---VYNNEGHVESRIVYYL------MN 460
            :.:.     :...|..::..:.:.|:|      |..|:   .|.::|..|:..:..:      :.
Human   344 KADECSTWIFHGSYSILNTSSSNSLTF------GDGVLERRPYEDQGLGETTPLTIICQPMQPLR 402

  Fly   461 IHITP----RTIYLTRHGE------SEYNLSGLI---------------------GG------DS 488
            ::..|    |.:::.||||      .:|.||...                     ||      |:
Human   403 VNSQPGPQKRCLFVCRHGERMDVVFGKYWLSQCFDAKGRYIRTNLNMPHSLPQRSGGFRDYEKDA 467

  Fly   489 NLSARG-------------------HQYAN--------ALSTFIAQQQIDGLRV--------WTS 518
            .::..|                   |.|.:        |.:.....||.:.|::        ||.
Human   468 PITVFGCMQARLVGEALLESNTIIDHVYCSPSLRCVQTAHNILKGLQQENHLKIRVEPGLFEWTK 532

  Fly   519 WMKRAIQTVADVKAPQERWKALNEIDAGHCE-EMTYEQIKEKFPEEFKARDVNKFAYRYPRGESY 582
            |       ||....|  .|...:|:.|.:.. :.||   :...|       ::|...    .|||
Human   533 W-------VAGSTLP--AWIPPSELAAANLSVDTTY---RPHIP-------ISKLVV----SESY 574

  Fly   583 EDLVAR----LEPVIMELERQG-NVLVVSHQAVLRC----LFAYFLDKSAD------ELPYL 629
            :..::|    .:.:|.|.:.:| |:|:|:|.:.|..    |.......|.|      ::|||
Human   575 DTYISRSFQVTKEIISECKSKGNNILIVAHASSLEACTCQLQGLSPQNSKDFVQMVRKIPYL 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pfrx	NP_477451.1	6PF2K	254..465	CDD:279872	36/249 (14%)
		AAA_33	256..412	CDD:290396	26/180 (14%)
		His_Phos_1	468..651	CDD:278716	48/246 (20%)
UBASH3B	XP_005271769.1	UBA_like_SF	<83..104	CDD:304366	3/16 (19%)
		SH3_UBASH3B	284..345	CDD:212869	9/78 (12%)
		HP_PGM_like	414..626	CDD:132718	44/234 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0406
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900