Protein Alignment Pfrx and Ubash3b

DIOPT Version :10

• Sequence 1: NP_477451.1
• Gene: Pfrx / 32938
• FlyBaseID: FBgn0027621
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: XP_006510695.1
• Gene: Ubash3b / 72828
• MGIID: 1920078
• Length: 779
• Species: Mus musculus
• Alignment Length: 809
• Identity: 149/809 - (18%)
• Similarity: 247/809 - (30%)
• Gaps: 336/809 - (41%)

  Fly     4 STATAPLYAGYKPLISSVTTDTDPD--------PDMAPSLSAEG--------TADQPQ------- 45
            :.||.|..|   |:.|..:....|:        |...||....|        :|.:||
Mouse    83 AAATGPRRA---PVASPGSVSLRPEIWEHRPHRPPRTPSPRRAGDGRPLSGHSAPRPQPSAWPRA 144

  Fly    46 -----KSQREG---EVKGASSEAQR-TKANPNQILSASNSSSIDEQDEDQ-----VGTL------ 90
                 ||.|.|   ..:..||..:| |.:.|....:.::......::|:.     .|.|
Mouse   145 RSCTAKSPRAGTACSARAQSSMGRRWTCSCPWAFPAPAHKKLWHPREEEAFRQHVTGWLFSHVGD 209

  Fly    91 -----PLPLLSINRRTPTLLPRPVPPSSTRFTSSYNDDLCTC-SNCAYSSFSSSSSSASSTSSSS 149
                 |||      |...|..||..|.:.:.:..:......| .|.|::.|...:.........|
Mouse   210 PFLDDPLP------REYVLYLRPTGPLAQKLSDFWQQSKQICGKNKAHNIFPHITLCQFFMCEDS 268

  Fly   150 TSATAAGTALASAAASAVAKKLARSVTATSIMDMPYNTSP--SLRVRTTSLNQLKK-TADLAIE- 210
             ...|.|.||.:..:....|     .:|...::: |.:|.  .|.|:..|...||| .||.|.|
Mouse   269 -KVDALGEALQTTVSRWKCK-----FSAPLPLEL-YTSSNFIGLFVKEDSAEVLKKFAADFAAEA 326

  Fly   211 ---NELHVCPSVMSEELRKLLPPTSETVMTKPFPIRGERTIADCTTPHVIAMVGLPARGKTFISK 272
               .|:||                                     .||               .|
Mouse   327 ASKTEVHV-------------------------------------EPH---------------KK 339

  Fly   273 KLARYLNWIGISTRVFNLGEYRRHATTAYKSHEFFRADNEEAMAIRNRCANQALHDSCDWLLSGQ 337
            :|                     |.|.||    .|:|.:  ...:.....|..:...|||:
Mouse   340 QL---------------------HVTLAY----HFQASH--LPTLEKLAQNIDVKLGCDWV---- 373

  Fly   338 GSIAVFDATNSTRDRRQLIHDIVVKQHGFRLFFVESICDDPQII----EQNILEVKVSSPDYLNM 398
                   ||..:||.|...|:.:                  |:|    .||..|:::...|::.|
Mouse   374 -------ATIFSRDIRFANHETL------------------QVIYPYSPQNDDELELVPGDFIFM 413

  Fly   399 N---------------------TELVVRDFLQRIEH-----YEERYQPIDEVTESHLSFMKVYNA 437
            :                     :.|:..:::.:.:.     :...|..::.|:.|.|:|
Mouse   414 SPMEQTSTSEGWIYGTSLTTGCSGLLPENYITKADECSTWIFHGSYSILNTVSSSSLAF------ 472

  Fly   438 GKKVV---VYNNEGHVESRIVYYL------MNIHITP----RTIYLTRHGE------SEYNLSGL 483
            |...:   .|.::|..|:..:..:      :.::..|    |.:::.||||      .:|.||..
Mouse   473 GDGALERRQYEDQGLGETTPLTIICQPMQPLRVNSQPGPQKRCLFVCRHGERMDVVFGKYWLSQC 537

  Fly   484 I---------------------GG------DSNLSARG-------------------HQYAN--- 499
            .                     ||      |:.::..|                   |.|.:
Mouse   538 FDAKGRYIRTNLNMPHSLPQRSGGFRDYEKDAPITVFGCMQARLVGEALLESNTVIDHVYCSPSL 602

  Fly   500 -----ALSTFIAQQQIDGLRV--------WTSWMKRAIQTVADVKAPQERWKALNEIDAGHCE-E 550
                 |.:.....||.:.|::        ||.|       ||....|  .|...:|:.|.:.. :
Mouse   603 RCVQTAHNILKGLQQDNHLKIRVEPGLFEWTKW-------VAGSTLP--AWIPPSELAAANLSVD 658

  Fly   551 MTYEQIKEKFPEEFKARDVNKFAYRYPRGESYEDLVAR----LEPVIMELERQG-NVLVVSHQAV 610
            .||   :...|       |:|.|.    .|||:..:.|    .:.:|.|.:.:| |:|:|:|.:.
Mouse   659 TTY---RPHIP-------VSKLAI----SESYDTYINRSFQVTKEIISECKSKGNNILIVAHASS 709

  Fly   611 LRC----LFAYFLDKSAD------ELPYL 629
            |..    |.......|.|      ::|||
Mouse   710 LEACTCQLQGLSPQNSKDFVQMVRKIPYL 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pfrx	NP_477451.1	6PF2K	254..465	CDD:396253	37/249 (15%)
		His_Phos_1	468..651	CDD:459751	50/246 (20%)
Ubash3b	XP_006510695.1	PRK12323	<66..>164	CDD:481241	18/83 (22%)
		SH3_UBASH3B	386..447	CDD:212869	9/78 (12%)
		HP_PGM_like	516..728	CDD:132718	46/234 (20%)