DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pfrx and ubash3bb

DIOPT Version :9

Sequence 1:	NP_477451.1	Gene:	Pfrx / 32938	FlyBaseID:	FBgn0027621	Length:	716	Species:	Drosophila melanogaster
Sequence 2:	NP_001122227.1	Gene:	ubash3bb / 569827	ZFINID:	ZDB-GENE-080724-6	Length:	642	Species:	Danio rerio

Alignment Length:	368	Identity:	74/368 - (20%)
Similarity:	123/368 - (33%)	Gaps:	119/368 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   137 SSSSSASSTSSSSTSATAAGTALASAAASAVAKKLARSVT-----ATSIMDMPYNTSPS------ 190
            ||:....|||......|:.||.::.............|.|     :.|.    :.||||
Zfish   272 SSTLEQMSTSEGWVYGTSLGTGISGLLPENYVSPADESDTWVFHGSHSF----FCTSPSEKGCKE 332

  Fly   191 -------LRVRTTSLNQLKKTADLAIENELHVCP--SVMSEELRKLLPPTSETV------MTKPF 240
                   |.:|....::|.::|.|::     :|.  .|:...::...|..:..|      |...|
Zfish   333 TKALDGLLNIRCFENSRLGESAILSV-----ICQPMQVLRSNIQSRAPKRTLFVCRHGERMDVVF 392

  Fly   241 PIRGERTIADCTTP-------HVIAMVGLPARGKTFISKKLARYLNWIGISTRVFNLGEYRRHAT 298
               |:..::.|:..       ::.....|||||.|....::...:..:| ||:...:||....:.
Zfish   393 ---GKHWLSQCSDSKGRYVRRNLNMPAALPARGATHRDYEMDAPITVVG-STQAKIVGEALLESN 453

  Fly   299 TA----YKSHEFFRADNEEAMAIRNRCANQALHDSCDWLLSGQGSIAVFDATNSTRDRRQLIHDI 359
            |:    |.|...             ||.                               |..|:|
Zfish   454 TSIDFVYCSPSL-------------RCV-------------------------------QTAHEI 474

  Fly   360 V--VKQHGFRLFFVESICDDPQIIEQNILEVKVSSPDYL--------NMNTELVVRDF-----LQ 409
            :  ::|.| ||    ||..:|.:.|........|.|.::        |:|.:...|..     |.
Zfish   475 LRGMQQEG-RL----SIRVEPGLFEWTKWVSGTSLPAWIPPTDLAAANLNVDTTYRPHMPISKLT 534

  Fly   410 RIEHYEERYQPIDEVTESHLSFMKVYNAGKKVVVYNNEGHVES 452
            ..|.||......::||:..|::.|  |.||.::..   ||..|
Zfish   535 VSEAYETYISRSNQVTKDILAYCK--NKGKNILFV---GHASS 572

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pfrx	NP_477451.1	6PF2K	254..465	CDD:279872	46/225 (20%)
		AAA_33	256..412	CDD:290396	33/174 (19%)
		His_Phos_1	468..651	CDD:278716
ubash3bb	NP_001122227.1	UBA_UBS3B	28..65	CDD:270486
		SH3_UBASH3B	245..306	CDD:212869	8/33 (24%)
		HP_PGM_like	378..613	CDD:132718	51/253 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0406
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900