Protein Alignment Pfrx and Pfkfb4

DIOPT Version :10

• Sequence 1: NP_477451.1
• Gene: Pfrx / 32938
• FlyBaseID: FBgn0027621
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: XP_036010927.1
• Gene: Pfkfb4 / 270198
• MGIID: 2687284
• Length: 544
• Species: Mus musculus
• Alignment Length: 493
• Identity: 245/493 - (49%)
• Similarity: 312/493 - (63%)
• Gaps: 70/493 - (14%)

  Fly   224 LRKLLPPTSETVMTKPFPIRGERTIADCTTPHVIAMVGLPARGKTFISKKLARYLNWIGISTRVF 288
            |:|:..|.|.   .:|.....:|.:.....|.:|.||||||||||:|||||.|||||||:.||.|
Mouse    12 LKKIWMPYSN---GRPALHASQRGVCMTNCPTLIVMVGLPARGKTYISKKLTRYLNWIGVPTREF 73

  Fly   289 NLGEYRRHATTAYKSHEFFRADNEEAMAIRNRCANQALHDSCDWLLSGQGSIAVFDATNSTRDRR 353
            |:|:|||.....|||.|||..||||.:.||.:||..||.|...:|....|.:|||||||:||:||
Mouse    74 NVGQYRRDIVKTYKSFEFFLPDNEEGLKIRKQCALAALSDVRKFLSEEGGHVAVFDATNTTRERR 138

  Fly   354 QLIHDIVVKQHGFRLFFVESICDDPQIIEQNILEVKVSSPDYLNMNTELVVRDFLQRIEHYEERY 418
            .:|.:. .:|:|::.|||||||.||:::..||::||:.||||:|.:::....||::|||.||..|
Mouse   139 AMIFNF-GEQNGYKTFFVESICVDPEVVAANIVQVKLGSPDYVNRDSDEATEDFMRRIECYENSY 202

  Fly   419 QPIDE------VTESH------------------------------------------------- 428
            :.:||      ..|.|
Mouse   203 ESLDEDLDRATAREPHPEQPQLDLSANVAPGVIGRVKIQWAESQAFQLVPVAAGVLPRAWPPSQA 267

  Fly   429 ---------LSFMKVYNAGKKVVVYNNEGHVESRIVYYLMNIHITPRTIYLTRHGESEYNLSGLI 484
                     ||::|:.:.|:..||.....|::|||||||||||:|||:|||.||||||.||.|.|
Mouse   268 LSTFSLARDLSYIKIMDVGQSYVVNRVADHIQSRIVYYLMNIHVTPRSIYLCRHGESELNLKGRI 332

  Fly   485 GGDSNLSARGHQYANALSTFIAQQQIDGLRVWTSWMKRAIQTVADVKAPQERWKALNEIDAGHCE 549
            |||..||.||.:::..|:.||:.|.|..|:||||.|||.|||...:..|.|:||.|||||||.||
Mouse   333 GGDPGLSPRGREFSKHLAQFISDQNIKDLKVWTSQMKRTIQTAEALSVPYEQWKVLNEIDAGVCE 397

  Fly   550 EMTYEQIKEKFPEEFKARDVNKFAYRYPRGESYEDLVARLEPVIMELERQGNVLVVSHQAVLRCL 614
            |||||:|::.:|.||..||.:|:.||||:||||||||.||||||||||||.||||:.||||:|||
Mouse   398 EMTYEEIQDHYPLEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCL 462

  Fly   615 FAYFLDKSADELPYLYVPLHTVIKLTPVAYGCKVEHIK 652
            .||||||:|:|||||..|||||:|||||||.|:  ||:
Mouse   463 LAYFLDKAAEELPYLKCPLHTVLKLTPVAYECR--HIQ 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pfrx	NP_477451.1	6PF2K	254..465	CDD:396253	113/274 (41%)
		His_Phos_1	468..651	CDD:459751	121/182 (66%)
Pfkfb4	XP_036010927.1	6PF2K	30..313	CDD:396253	114/283 (40%)
		His_Phos_1	316..495	CDD:459751	120/178 (67%)