Protein Alignment Pfrx and Pfkfb2

DIOPT Version :9

• Sequence 1: NP_477451.1
• Gene: Pfrx / 32938
• FlyBaseID: FBgn0027621
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_001355772.1
• Gene: Pfkfb2 / 18640
• MGIID: 107815
• Length: 533
• Species: Mus musculus
• Alignment Length: 414
• Identity: 260/414 - (62%)
• Similarity: 320/414 - (77%)
• Gaps: 2/414 - (0%)

  Fly   253 TPHVIAMVGLPARGKTFISKKLARYLNWIGISTRVFNLGEYRRHATTAYKSHEFFRADNEEAMAI 317
            :|.:|.|:||||||||::||||.|||||||:.|:|||||.|||.|..:|:|::|||.||||||.|
Mouse    39 SPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYQSYDFFRHDNEEAMKI 103

  Fly   318 RNRCANQALHDSCDWLLSGQGSIAVFDATNSTRDRRQLIHDIVVKQHGFRLFFVESICDDPQIIE 382
            |.:||..||.|...:.....|.||||||||:||:||.:|.:. .||:.|::|||||:||||.:|.
Mouse   104 RKQCALVALEDVKAYFTEESGQIAVFDATNTTRERRDMILNF-AKQNAFKVFFVESVCDDPDVIA 167

  Fly   383 QNILEVKVSSPDYLNMNTELVVRDFLQRIEHYEERYQPID-EVTESHLSFMKVYNAGKKVVVYNN 446
            .||||||||||||...|.|.|:.|||:|||.|:..|||:| :..:..|||:||.|.|::.:|...
Mouse   168 ANILEVKVSSPDYPERNRENVMEDFLKRIECYKVTYQPLDPDNYDKDLSFIKVINVGQRFLVNRV 232

  Fly   447 EGHVESRIVYYLMNIHITPRTIYLTRHGESEYNLSGLIGGDSNLSARGHQYANALSTFIAQQQID 511
            :.:::|:|||||||||:.||||||.||||||:||.|.|||||.||.||.|:|:||..|:.:|:|.
Mouse   233 QDYIQSKIVYYLMNIHVHPRTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAHALKKFLEEQEIQ 297

  Fly   512 GLRVWTSWMKRAIQTVADVKAPQERWKALNEIDAGHCEEMTYEQIKEKFPEEFKARDVNKFAYRY 576
            .|:||||.:||.|||...:....|:||.|||||||.||||||.:|::::||||..||..|:.|||
Mouse   298 DLKVWTSQLKRTIQTAESLGVTYEQWKILNEIDAGVCEEMTYSEIEQRYPEEFALRDQEKYLYRY 362

  Fly   577 PRGESYEDLVARLEPVIMELERQGNVLVVSHQAVLRCLFAYFLDKSADELPYLYVPLHTVIKLTP 641
            |.||||:|||.||||||||||||||:||:|||||:|||.||||||.|||||||..|||.:.||||
Mouse   363 PGGESYQDLVQRLEPVIMELERQGNILVISHQAVMRCLLAYFLDKGADELPYLRCPLHIIFKLTP 427

  Fly   642 VAYGCKVEHIKLPIDAVDTHRPKP 665
            ||||||||.|.|.:|||||||.||
Mouse   428 VAYGCKVETITLNVDAVDTHRDKP 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pfrx	NP_477451.1	6PF2K	254..465	CDD:279872	121/211 (57%)
		AAA_33	256..412	CDD:290396	95/155 (61%)
		His_Phos_1	468..651	CDD:278716	125/182 (69%)
Pfkfb2	NP_001355772.1	6PF2K	31..251	CDD:334602	121/212 (57%)
		His_Phos_1	254..437	CDD:333990	125/182 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	447..492		4/5 (80%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838128
Domainoid	1	1.000	275	1.000	Domainoid score	I1740
eggNOG	1	0.900	-	-		E1_COG0406
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	541	1.000	Inparanoid score	I1160
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55027
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000312
OrthoInspector	1	1.000	-	-		otm43477
orthoMCL	1	0.900	-	-		OOG6_100250
Panther	1	1.100	-	-	O	PTHR10606
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1920
SonicParanoid	1	1.000	-	-		X325
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.830