DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pfrx and F09C12.8

DIOPT Version :9

Sequence 1:	NP_477451.1	Gene:	Pfrx / 32938	FlyBaseID:	FBgn0027621	Length:	716	Species:	Drosophila melanogaster
Sequence 2:	NP_494948.2	Gene:	F09C12.8 / 173881	WormBaseID:	WBGene00017279	Length:	306	Species:	Caenorhabditis elegans

Alignment Length:	282	Identity:	59/282 - (20%)
Similarity:	95/282 - (33%)	Gaps:	76/282 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   444 YN---NEGHVE-SRIVYYLMNIHITPRTIYLTRHGE----------SEYNLSGLIGG-DSNLSAR 493
            ||   |..|.: ||..::...|:::|..:.:.||.|          .:.|..|.... |.|:..|
Worm    20 YNCPSNRDHRDSSRRAHHPNEIYVSPTVMMVMRHSERVDDCCPGWIEKCNKEGKYEPFDLNMPTR 84

  Fly   494 -----------GHQYANALSTFIAQQQIDGLR--------VWTSWMKRAIQTVADVKAPQERWKA 539
                       ...........:||....||.        ::.|...|.|||...|: .....||
Worm    85 LPIQRPLKDYTRDTCITRSGAVLAQMIGRGLLMTDNTPDVIYCSPSLRCIQTATWVR-EMSGSKA 148

  Fly   540 LNEIDAGHCEEMTY--------EQI-KEKFPEEFKARDVNKFAYRYPRGESYEDLVARLEPV--- 592
            |..::.|..|...|        .|: :..||.:...|..........:.|:.::..||::.:
Worm   149 LLRVEPGLFENFHYPHGVPRFISQLQRHVFPVDKTFRPFLSLETVVGKQETNDEYNARIQLILNA 213

  Fly   593 ------IMELERQGNVLVVSH-----------QAVLRCLFAYFLDKSADELPY-----------L 629
                  :..:|::..||||:|           :.|.|.:....||..|..:||           .
Worm   214 IADQSEVSTVEKELKVLVVAHASTVDMAVGLLREVPRKIREEELDNIAIPVPYCSLAYLKKKCNY 278

  Fly   630 YVP-LHTVIKLTPVAYGCKVEH 650
            :|| .|.|..:|......|..|
Worm   279 WVPAAHQVPSVTYEFLTTKYNH 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pfrx	NP_477451.1	6PF2K	254..465	CDD:279872	7/24 (29%)
		AAA_33	256..412	CDD:290396
		His_Phos_1	468..651	CDD:278716	51/254 (20%)
F09C12.8	NP_494948.2	PGAM	97..238	CDD:214859	29/141 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0406
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900