Protein Alignment Pfrx and pfkb-1.1

DIOPT Version :9

• Sequence 1: NP_477451.1
• Gene: Pfrx / 32938
• FlyBaseID: FBgn0027621
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_001379749.1
• Gene: pfkb-1.1 / 172147
• WormBaseID: WBGene00022456
• Length: 450
• Species: Caenorhabditis elegans
• Alignment Length: 422
• Identity: 236/422 - (55%)
• Similarity: 306/422 - (72%)
• Gaps: 9/422 - (2%)

  Fly   254 PHVIAMVGLPARGKTFISKKLARYLNWIGISTRVFNLGEYRRHATTAYK--SHEFFRADNEEAMA 316
            |:|||:|||||||||:||.||.||||||||.|:.||:|||||.|....:  .:|||..:|.....
 Worm    29 PNVIALVGLPARGKTYISHKLCRYLNWIGIKTKAFNVGEYRRRACNLEEEGENEFFSPNNARGQK 93

  Fly   317 IRNRCANQALHDSCDWLLSGQGSIAVFDATNSTRDRRQLIHDI---VVKQHGFRLFFVESICDDP 378
            ||:.||..|:.|...:|.:.:|.:|:.||||:|||||:|:.:.   ::.:..||:|||||:||||
 Worm    94 IRDECAKLAIEDMGRYLDNKEGEVAILDATNTTRDRRKLLMEFCRNMMHEPPFRVFFVESVCDDP 158

  Fly   379 QIIEQNILEVKVSSPDYLN-MNTELVVRDFLQRIEHYEERYQPIDEVTESHLSFMKVYNAGKKVV 442
            .||..||.|||::||||.. |:.|....|||:|||:|..:|:|:||..:..||::||.||||...
 Worm   159 DIINSNITEVKINSPDYKGIMSQEEAKEDFLKRIENYRMQYEPLDEDHDEELSYIKVINAGKSFY 223

  Fly   443 VYNNEGHVESRIVYYLMNIHITPRTIYLTRHGESEYNLSGLIGGDSNLSARGHQYANALSTFIAQ 507
            |:|..|||:||:||:|||||:.||:|||:||||||||..|.:||||.||..|..||..|..:..:
 Worm   224 VHNVNGHVQSRVVYFLMNIHLLPRSIYLSRHGESEYNRIGRLGGDSPLSENGLNYAGKLREYFEK 288

  Fly   508 QQIDGLRVWTSWMKRAIQTVA---DVKAPQERWKALNEIDAGHCEEMTYEQIKEKFPEEFKARDV 569
            :.:|..|||:|...||.||.:   |:....|.||.|:|||||.||.:|||..:.::|::|..||.
 Worm   289 EDLDDFRVWSSQKIRAAQTASHLKDLAGHTEFWKCLDEIDAGICEGLTYEDFEARYPKQFAERDK 353

  Fly   570 NKFAYRYPRGESYEDLVARLEPVIMELERQGNVLVVSHQAVLRCLFAYFLDKSADELPYLYVPLH 634
            :|:.||||.|||||||||||||||||||||.||||:||||||||:.|||.:|:.|:||||.||||
 Worm   354 DKYHYRYPSGESYEDLVARLEPVIMELERQSNVLVISHQAVLRCILAYFTNKNRDDLPYLKVPLH 418

  Fly   635 TVIKLTPVAYGCKVEHIKLPIDAVDTHRPKPK 666
            |||||||.||.|::|..|..|:||:|:|.||:
 Worm   419 TVIKLTPKAYSCEIELFKFDIEAVNTYREKPQ 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pfrx	NP_477451.1	6PF2K	254..465	CDD:279872	114/216 (53%)
		AAA_33	256..412	CDD:290396	84/161 (52%)
		His_Phos_1	468..651	CDD:278716	112/185 (61%)
pfkb-1.1	NP_001379749.1	6PF2K	29..246	CDD:396253	114/216 (53%)
		His_Phos_1	249..435	CDD:395236	112/185 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159971
Domainoid	1	1.000	231	1.000	Domainoid score	I1378
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	474	1.000	Inparanoid score	I823
Isobase	1	0.950	-	0	Normalized mean entropy	S630
OMA	1	1.010	-	-		QHG55027
OrthoDB	1	1.010	-	-		D232517at33208
OrthoFinder	1	1.000	-	-		FOG0000312
OrthoInspector	1	1.000	-	-		otm14659
orthoMCL	1	0.900	-	-		OOG6_100250
Panther	1	1.100	-	-	O	PTHR10606
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1920
SonicParanoid	1	1.000	-	-		X325
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.890