Protein Alignment Pfrx and pfkfb3

DIOPT Version :10

• Sequence 1: NP_477451.1
• Gene: Pfrx / 32938
• FlyBaseID: FBgn0027621
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: XP_012814166.1
• Gene: pfkfb3 / 100216216
• XenbaseID: XB-GENE-963652
• Length: 510
• Species: Xenopus tropicalis
• Alignment Length: 495
• Identity: 250/495 - (50%)
• Similarity: 332/495 - (67%)
• Gaps: 24/495 - (4%)

  Fly   224 LRKLLPPTSETVMTKPFPIRGERTIADCTTPHVIAMVGLPARGKTFISKKLARYLNWIGISTRVF 288
            ::|:..|..| :...|..:.|.:.   ..:|.||.||||||||||:|||||.|||||.|:.|:||
 Frog    10 IKKIWLPRDE-LPQLPINVGGPQF---ANSPTVIVMVGLPARGKTYISKKLTRYLNWSGVPTKVF 70

  Fly   289 NLGEYRRHATTAYKSHEFFRADNEEAMAIRNRCANQALHDSCDWLLSGQGSIAVFDATNSTRDRR 353
            |:|||||.|...:.||:|||:||:|||.||..||..||.|...:|....|.||||||||:||:||
 Frog    71 NVGEYRREAVKDFSSHDFFRSDNKEAMKIRRHCALAALADVKSYLTKEGGQIAVFDATNTTRERR 135

  Fly   354 QLIHDIVVKQHGFRLFFVESICDDPQIIEQNILEVKVSSPDYLNMNTELVVRDFLQRIEHYEERY 418
            .::.|. .|::.|::||:||:||||.::..|:||||:|||||....:...:.||::||..|:..|
 Frog   136 SIVVDF-AKENEFKVFFIESVCDDPAVVASNVLEVKLSSPDYKGCTSNEALEDFMKRINCYKNSY 199

  Fly   419 QPID-EVTESHLSFMKVYNAGKKVVVYNNEGHVESRIVYYLMNIHITPRTIYLTRHGESEYNLSG 482
            :|:| :..:..||.:.|.:.|::.:|...:.|::|:|||||||||:.||.|||.|.||||.||..
 Frog   200 EPLDPDQHDRDLSMIIVIDVGRRFLVNRVQDHIQSKIVYYLMNIHVQPRCIYLCRAGESESNLKE 264

  Fly   483 LIGGDSNLSARGHQYANALSTFIAQQQIDGLRVWTSWMKRAIQTVADVKAPQERWKALNEIDAGH 547
            .|||||.||.||.::|.||..::..|.:..|:||||.:||.|||...:|.|.|:||||||:|||.
 Frog   265 KIGGDSGLSHRGKKFAVALKKYVEDQNLKELKVWTSQLKRTIQTAEALKMPYEQWKALNELDAGV 329

  Fly   548 CEEMTYEQIKEKFPEEFKARDVNKFAYRYPRGESYEDLVARLEPVIMELERQGNVLVVSHQAVLR 612
            |||.|||:|||.:|||:..|..:|:.||||.||||:|||.|||||||||||||||||:.||||:|
 Frog   330 CEEKTYEEIKELYPEEYALRAQDKYHYRYPSGESYQDLVQRLEPVIMELERQGNVLVICHQAVMR 394

  Fly   613 CLFAYFLDKSADELPYLYVPLHTVIKLTPVAYGCKVEHIKLPIDAVDTHR----------PKPKI 667
            ||.:|||||.|||:|||..|||:::||||.||||.||.:...:|||:|||          |.|.:
 Frog   395 CLLSYFLDKPADEMPYLKCPLHSMLKLTPFAYGCHVEIVPFNVDAVNTHRDRIIEDCKKGPNPLM 459

  Fly   668 PGDVSEPGLDGLSGELVAPDGVGKVLIVGDDVATATNGNG 707
            ..:...|        |.:|:...|..|...:...|.:.:|
 Frog   460 RRNSVTP--------LASPEPTKKARINSFEEFAACSSHG 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pfrx	NP_477451.1	6PF2K	254..465	CDD:396253	110/211 (52%)
		His_Phos_1	468..651	CDD:459751	118/182 (65%)
pfkfb3	XP_012814166.1	6PF2K	29..247	CDD:396253	111/221 (50%)
		His_Phos_1	250..431	CDD:459751	116/180 (64%)