Protein Alignment Naa15-16 and NAT1

DIOPT Version :10

• Sequence 1: NP_573384.1
• Gene: Naa15-16 / 32934
• FlyBaseID: FBgn0031020
• Length: 890
• Species: Drosophila melanogaster
• Sequence 2: NP_010244.1
• Gene: NAT1 / 851521
• SGDID: S000002198
• Length: 854
• Species: Saccharomyces cerevisiae
• Alignment Length: 834
• Identity: 247/834 - (29%)
• Similarity: 410/834 - (49%)
• Gaps: 99/834 - (11%)

  Fly     3 SSDPLP------PKEGALFRKLLKCYELKQYKNGLKLAKQILSNPKYMEHGETLAMKGLTLNGLG 61
            |:.|.|      .||...|.:.||.||.||||..|||...||.  |...|.::||:|||.|..:|
Yeast     6 STKPKPAAKIALKKENDQFLEALKLYEGKQYKKSLKLLDAILK--KDGSHVDSLALKGLDLYSVG 68

  Fly    62 RREEAYKYVRLGLR---NDLRSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWEKDNLQILKDLSL 123
            .:::|..||...:|   ....|.:|.||.|:..|:.|:|.|:||.:..||.....|.||.:||:.
Yeast    69 EKDDAASYVANAIRKIEGASASPICCHVLGIYMRNTKEYKESIKWFTAALNNGSTNKQIYRDLAT 133

  Fly   124 LQIQMRDLEGYKETRHHLFTLRPSQHASWIGFAMSYHLLGDYDMANSILETFSQ-SQTSI-EAHD 186
            ||.|:.|.:....:|...:.......|:|...|::..:.|:...|.:.|..|.: ::..| ::..
Yeast   134 LQSQIGDFKNALVSRKKYWEAFLGYRANWTSLAVAQDVNGERQQAINTLSQFEKLAEGKISDSEK 198

  Fly   187 YRHSELLLYQNQILIES-----NRLQQAVDHLTKYQGQIVDKLAVRETMGDLYIKLQQQEKAVPI 246
            |.|||.|:|:|.|:.::     ::||..:.||...:..:.||..:.|....:|:||.|.:.|..:
Yeast   199 YEHSECLMYKNDIMYKAASDNQDKLQNVLKHLNDIEPCVFDKFGLLERKATIYMKLGQLKDASIV 263

  Fly   247 FESLIRRNPENVLYYEQYIAARQVT-DSSAVVSIYRVFQEQYPRALCPRRLPLN-IANGDEFRVV 309
            :.:||:|||:|..||:....:..:. |:....::|...::.|||...|:.:||. :.:.:|....
Yeast   264 YRTLIKRNPDNFKYYKLLEVSLGIQGDNKLKKALYGKLEQFYPRCEPPKFIPLTFLQDKEELSKK 328

  Fly   310 TDEYLRRGLRKGIPPLFVNVRTLHQIPER--AAVIEELALQYFENLTRSGHFSREDADAGIPVEP 372
            ..||:...|.:|:|..|.||:.|:|..:.  :.::|::.|.|...|.              |.:.
Yeast   329 LREYVLPQLERGVPATFSNVKPLYQRRKSKVSPLLEKIVLDYLSGLD--------------PTQD 379

  Fly   373 ASALVWTALFLAQHYDYMRDTDRALEYINVAIDHTPTLIELLITKGRIFKHAGDPVEAYVWLEEA 437
            ....:||..:|:||:.:::|..:|.|||:.|:||||||:|..|.|.||.||.|....|...|||.
Yeast   380 PIPFIWTNYYLSQHFLFLKDFPKAQEYIDAALDHTPTLVEFYILKARILKHLGLMDTAAGILEEG 444

  Fly   438 QSMDTADRYINSKCAKYMLRANMVQEAEEICAKFTR--EGVSAMDNLNEMQCMWFQTECALAYQR 500
            :.:|..||:||.|..||.||||.:.:|.|:.:.||:  :.|:.:.:|:.::..||..|.|.||.|
Yeast   445 RQLDLQDRFINCKTVKYFLRANNIDKAVEVASLFTKNDDSVNGIKDLHLVEASWFIVEQAEAYYR 509

  Fly   501 M--------------------------------GRW------GESLKKCHEVERHFAEIVEDQFD 527
            :                                .:|      |.:||:.:.:.:.:.:..:||.|
Yeast   510 LYLDRKKKLDDLASLKKEVESDKSEQIANDIKENQWLVRKYKGLALKRFNAIPKFYKQFEDDQLD 574

  Fly   528 FHTYCMRKMTLRAYVGLLRLEDVLRQHPFYFKAAKCAIEVYIRLYDKPLKSETTIEEIDIENLPP 592
            ||:|||||.|.|||:.:|.....|...|.|.:|.|.|.::|.:::|..||.::  :.:| ||  .
Yeast   575 FHSYCMRKGTPRAYLEMLEWGKALYTKPMYVRAMKEASKLYFQMHDDRLKRKS--DSLD-EN--S 634

  Fly   593 SELKKLRSKQRKAKKKAELESAQAAQAQVKREQHQKSKQQANQETDPDAPQLDELVAEKLERTDD 657
            .|::.........||||:.|:|    |..||:: .::|..|...:|.|    :::..|||..|..
Yeast   635 DEIQNNGQNSSSQKKKAKKEAA----AMNKRKE-TEAKSVAAYPSDQD----NDVFGEKLIETST 690

  Fly   658 PL-DKAIEFLKPLQQLAKERIETHLLAFELYYRKNKLLLMLQCIRR-ARAVDASHPVIHSCIIRF 720
            |: |.|.||........:|....::|.||..||..||.|....:.: |:....:..:..|..|..
Yeast   691 PMEDFATEFYNNYSMQVREDERDYILDFEFNYRIGKLALCFASLNKFAKRFGTTSGLFGSMAIVL 755

  Fly   721 VKSLTSAAKEQPFNEHVQQVLEKATKELIGSKTPQQLNDEFIAKHNASILHLYE 774
               |.:...:.||:..:::|:.|:.::......|  ||:  |:.::...|:.|:
Yeast   756 ---LHATRNDTPFDPILKKVVTKSLEKEYSENFP--LNE--ISNNSFDWLNFYQ 802

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Naa15-16	NP_573384.1	TPR repeat	13..39	CDD:276809	13/25 (52%)
		TPR	45..269	CDD:440225	71/233 (30%)
		TPR repeat	48..75	CDD:276809	10/26 (38%)
		TPR repeat	83..109	CDD:276809	11/25 (44%)
		TPR repeat	114..144	CDD:276809	10/29 (34%)
		TPR repeat	149..173	CDD:276809	5/23 (22%)
		NatA_aux_su	187..703	CDD:463630	170/566 (30%)
		TPR repeat	410..440	CDD:276809	13/29 (45%)
		TPR repeat	445..470	CDD:276809	12/24 (50%)
NAT1	NP_010244.1	LapB	23..303	CDD:442196	88/281 (31%)
		TPR repeat	24..48	CDD:276809	13/23 (57%)
		TPR repeat	53..83	CDD:276809	11/29 (38%)
		TPR repeat	91..118	CDD:276809	10/26 (38%)
		NatA_aux_su	199..736	CDD:463630	170/564 (30%)