Protein Alignment Naa15-16 and Naa15

DIOPT Version :10

• Sequence 1: NP_573384.1
• Gene: Naa15-16 / 32934
• FlyBaseID: FBgn0031020
• Length: 890
• Species: Drosophila melanogaster
• Sequence 2: NP_001101144.1
• Gene: Naa15 / 310399
• RGDID: 1310984
• Length: 865
• Species: Rattus norvegicus
• Alignment Length: 893
• Identity: 467/893 - (52%)
• Similarity: 627/893 - (70%)
• Gaps: 40/893 - (4%)

  Fly     1 MPSSDPLPPKEGALFRKLLKCYELKQYKNGLKLAKQILSNPKYMEHGETLAMKGLTLNGLGRREE 65
            ||:.. |||||.|||:::|:|||.|||:||||..||||||||:.||||||||||||||.||::||
  Rat     1 MPAVS-LPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLGKKEE 64

  Fly    66 AYKYVRLGLRNDLRSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWEKDNLQILKDLSLLQIQMRD 130
            ||:.||.||||||:|||||||||||||||||||||||||||||||:|||||||:|||||||||||
  Rat    65 AYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRD 129

  Fly   131 LEGYKETRHHLFTLRPSQHASWIGFAMSYHLLGDYDMANSILETFSQS-QTSIEAHDYRHSELLL 194
            ||||:|||:.|..|||:|.|||||:|::||||.||:||..|||.|.:: |||.:..||.:|||||
  Rat   130 LEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQTSPDKVDYEYSELLL 194

  Fly   195 YQNQILIESNRLQQAVDHLTKYQGQIVDKLAVRETMGDLYIKLQQQEKAVPIFESLIRRNPENVL 259
            ||||:|.|:...::|::||..|:.||.|||||.||.|:|.::|.:.|.|..::..|..|||||..
  Rat   195 YQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRLEDAADVYRGLQERNPENWA 259

  Fly   260 YYEQYIAARQVTDSSAVVSIYRVFQEQYPRALCPRRLPLNIANGDEFRVVTDEYLRRGLRKGIPP 324
            ||:....|.:..:....:.||.....::||.|.|||||||..:|::|:...|.:||....||.||
  Rat   260 YYKGLEKALKPANMLERLKIYEEAWTKFPRGLVPRRLPLNFLSGEKFKECLDRFLRMNFSKGCPP 324

  Fly   325 LFVNVRTLHQIPERAAVIEELALQYFENLTRSGHFSREDADAGIPVEPASALVWTALFLAQHYDY 389
            :|..:|:|::..|:.|::|||.:.|..:|.....|:..|..   ..||.:.|:|...:||||||.
  Rat   325 VFNTLRSLYRDKEKVAIVEELVVGYETSLKSCRLFNPNDDG---KEEPPTTLLWVQYYLAQHYDK 386

  Fly   390 MRDTDRALEYINVAIDHTPTLIELLITKGRIFKHAGDPVEAYVWLEEAQSMDTADRYINSKCAKY 454
            :.....||||||.||:.|||||||.:.|.:|:||||:..||..|::|||::|||||:||||||||
  Rat   387 IGQPSIALEYINTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKY 451

  Fly   455 MLRANMVQEAEEICAKFTREGVSAMDNLNEMQCMWFQTECALAYQRMGRWGESLKKCHEVERHFA 519
            ||:||:::||||:|:||||||.||::|||||||||||||||.||:.|.::||:||||||:||||.
  Rat   452 MLKANLIKEAEEMCSKFTREGTSAVENLNEMQCMWFQTECAQAYKAMNKFGEALKKCHEIERHFI 516

  Fly   520 EIVEDQFDFHTYCMRKMTLRAYVGLLRLEDVLRQHPFYFKAAKCAIEVYIRLYDKPLKSETTIEE 584
            ||.:||||||||||||:|||:||.||:|||||||||||||||:.|||:|::|:|.||..|....|
  Rat   517 EITDDQFDFHTYCMRKITLRSYVDLLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHE 581

  Fly   585 IDIENLPPSELKKLRSKQRKAKKKAELESAQAAQAQVKREQHQKSKQQANQ--ETDPDAPQL--- 644
            .|..|:...||||||:|||:|:|||::|.        :::..:|.|||.||  :.|.|..::
  Rat   582 ADTANMSDKELKKLRNKQRRAQKKAQIEE--------EKKNAEKEKQQRNQKKKKDDDDEEIGGP 638

  Fly   645 -DELVAEKLERTDDPLDKAIEFLKPLQQLAKERIETHLLAFELYYRKNKLLLMLQCIRRARAVDA 708
             :||:.|||.:.:.||::||:||.||:.|.|.:|||||.|||:|:||.|.|||||.::||.|:|:
  Rat   639 KEELIPEKLAKVETPLEEAIKFLTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDS 703

  Fly   709 SHPVIHSCIIRFVKSLTSAAKEQPFNEHVQQVLEKATKELIGSKTPQQLNDEFIAKHNASILHLY 773
            |||.:|.|:||...|:.. :|:.|  |.|:.||::....|.|:..|:..|:.|:.:::.|:.|..
  Rat   704 SHPWLHECMIRLFNSVCE-SKDLP--EAVRTVLKQEMNRLFGATNPKNFNETFLKRNSDSLPHRL 765

  Fly   774 EGARSLYELDNSKKAAAIKLVTSF--NLAKLRLEEATKIYTALRDGDVFGECEAEAASYQQACHQ 836
            ..|:.:|.||:|.:..||:|.|:.  :|....|:...::..||..|.: |:|:..|.:|:.:||:
  Rat   766 SAAKMIYYLDSSSQKRAIELATTLDGSLTNRNLQTCMEVLEALCGGSL-GDCKEAAEAYRVSCHK 829

  Fly   837 RFQYARIFRNVEELEAQLQEKEAAKLRAEEEQQQLIHVDSSEPVSVLA 884
            .|.||..|               .....||:.:..::.|||.....||
  Rat   830 LFPYALAF---------------MPPGYEEDMKITVNGDSSAETEELA 862

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Naa15-16	NP_573384.1	TPR repeat	13..39	CDD:276809	17/25 (68%)
		TPR	45..269	CDD:440225	150/224 (67%)
		TPR repeat	48..75	CDD:276809	20/26 (77%)
		TPR repeat	83..109	CDD:276809	25/25 (100%)
		TPR repeat	114..144	CDD:276809	24/29 (83%)
		TPR repeat	149..173	CDD:276809	15/23 (65%)
		NatA_aux_su	187..703	CDD:463630	271/521 (52%)
		TPR repeat	410..440	CDD:276809	16/29 (55%)
		TPR repeat	445..470	CDD:276809	18/24 (75%)
Naa15	NP_001101144.1	TPR repeat	12..38	CDD:276809	17/25 (68%)
		TPR	44..283	CDD:440225	152/238 (64%)
		TPR repeat	47..74	CDD:276809	20/26 (77%)
		TPR repeat	82..108	CDD:276809	25/25 (100%)
		TPR repeat	113..143	CDD:276809	24/29 (83%)
		TPR repeat	148..173	CDD:276809	16/24 (67%)
		NatA_aux_su	187..698	CDD:463630	271/521 (52%)
		TPR repeat	378..402	CDD:276809	13/23 (57%)
		TPR repeat	407..437	CDD:276809	16/29 (55%)
		TPR repeat	442..467	CDD:276809	18/24 (75%)