Protein Alignment Naa15-16 and hpo-29

DIOPT Version :10

• Sequence 1: NP_573384.1
• Gene: Naa15-16 / 32934
• FlyBaseID: FBgn0031020
• Length: 890
• Species: Drosophila melanogaster
• Sequence 2: NP_497180.3
• Gene: hpo-29 / 175189
• WormBaseID: WBGene00021754
• Length: 852
• Species: Caenorhabditis elegans
• Alignment Length: 826
• Identity: 327/826 - (39%)
• Similarity: 510/826 - (61%)
• Gaps: 33/826 - (3%)

  Fly     3 SSDPLPPKEGALFRKLLKCYELKQYKNGLKLAKQILSNPKYMEHGETLAMKGLTLNGLGRREEAY 67
            ||.|||.||...|:|::|.||.||||.|||.|::||::|.:.|||||||||||.||.:|:.:||.
 Worm     9 SSQPLPAKELGYFKKIVKSYEQKQYKAGLKFAQKILTSPGFAEHGETLAMKGLILNCMGKLQEAQ 73

  Fly    68 KYVRLGLRNDLRSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWEKDNLQILKDLSLLQIQMRDLE 132
            ..||.||.:||||:|||||:||:|:::||||||||.|:.||..||||||||:|||||||.:||.:
 Worm    74 DCVRRGLVSDLRSYVCWHVFGLIQKTEKKYDEAIKAYKRALMLEKDNLQILRDLSLLQIHIRDYD 138

  Fly   133 GYKETRHHLFTLRPSQHASWIGFAMSYHLLGDYDMANSILETFSQSQTSIEAHDYRHSELLLYQN 197
            ||..:::.|..||.:|..||:|:.:::|||.::::|..|:..:.::.|. ..:|:..|||:||||
 Worm   139 GYLSSKYELLQLRQTQRVSWLGYIVAHHLLKEHNLALGIMAEYIKNNTP-SGYDFEFSELILYQN 202

  Fly   198 QILIESNRLQQAVDHLTKYQGQIVDKLAVRETMGDLYIKLQQQEKAVPIFESLIRRNPENVLYYE 262
            .|:.|:.....|:..|.:....||||:|..||..:|.:.|:|.::|..::.:||.|||:::.||:
 Worm   203 LIMREAGLPDVALQKLEENSTHIVDKVAYMETRANLLMDLEQPKQAENVWRALIERNPDSLEYYD 267

  Fly   263 QYIAARQVTDS-SAVVSIYRVFQEQYPRALCPRRLPLNIANGDEFRVVTDEYLRRGLRKGIPPLF 326
            .......:.|| .|.:::.....|::.||..||||.|.:..|:|.|....|::...||||.|.||
 Worm   268 MLEKCMGIKDSPKAQLAMLDGLAEKFKRAAAPRRLALYLVEGEELRRRLHEWMIPMLRKGAPSLF 332

  Fly   327 VNVRTLHQIPERAAVIEELALQYFENLTRSGH--FSREDADAGIPVEPASALVWTALFLAQHYDY 389
            .::..|::.|::.||||.|..:|.:.:...|:  .|.:..|.  ..||.:..:|..:..:.|:|.
 Worm   333 ASLVPLYKYPQKQAVIESLITEYVKKMDDEGYGNVSLDGKDQ--ECEPPTTALWLYVLASHHFDR 395

  Fly   390 MRDTDRALEYINVAIDHTPTLIELLITKGRIFKHAGDPVEAYVWLEEAQSMDTADRYINSKCAKY 454
            ...|..||.||..||.||||::|..:.|.||:|||||..||..|:|||||:||||||||.||.||
 Worm   396 CGMTQLALNYIERAIQHTPTVVENYMLKARIYKHAGDYDEAARWMEEAQSLDTADRYINGKCGKY 460

  Fly   455 MLRANMVQEAEEICAKFTREGVSAMDNLNEMQCMWFQTECALAYQRMGRWGESLKKCHEVERHFA 519
            :|||....||.::.|||||||.:|..:|.:|||||::.|...|::.:.::||:|:|.|.::.||.
 Worm   461 LLRAKRSDEANKMLAKFTREGENAASHLTDMQCMWYELESGRAFRSVNKYGEALRKAHHIDFHFN 525

  Fly   520 EIVEDQFDFHTYCMRKMTLRAYVGLLRLEDVLRQHPFYFKAAKCAIEVYIRLYDKP--LKSETTI 582
            ..:|||:||||||:|||||.:|:.|||:.|.||...:|::.||.||::|:|:.|:|  :...:.:
 Worm   526 TWIEDQYDFHTYCLRKMTLCSYIRLLRMCDKLRDADYYYQGAKLAIKIYLRMIDRPDDMNEHSAL 590

  Fly   583 EEIDIENLPPSELKKLRSKQRKAKKKAELESAQAAQAQVKREQHQKSKQQANQETDPDAPQLDEL 647
            .:   |.:...|:||::   :|.||:.||        |.:.|:.:|.|:| .:|.....||:|
 Worm   591 IK---EGMTDQEIKKMK---KKLKKQKEL--------QEEEEKKKKDKEQ-KEEGLQRGPQID-- 638

  Fly   648 VAEKLERTDDPLDKAIEFLKPLQQLAKERIETHLLAFELYYRKNKLLLMLQCIRRARAVDASHPV 712
             ||.|.:|:|||.:|.:|...:.....:::..:.|..|:|.||.|:||.|:|:......:.:||:
 Worm   639 -AEALLKTEDPLGEAAKFCHNIHTFGTQKVTGYALCAEVYRRKGKVLLALKCLNEGEDREPTHPL 702

  Fly   713 IHSCIIRFVKSLTSAAKEQPFNEHVQQVLEKATKELIGS-KTPQQLNDEFIAKHNASILHLYEGA 776
            :|   ::.||.|....|.: .:..|::..::..|.:.|: :...:||::|..:|.....|....|
 Worm   703 LH---VQKVKFLAYWPKCE-LSGLVKETADELMKCVYGAERDAAELNEKFKIEHQHDFAHRLAYA 763

  Fly   777 RSLYELDNSKKAAAIKLVTSFNLAKLRLEEATKIYTALRDGDVFGE 822
            .:.|.:|:|....: .::.|...:|:. ..:.|:...|:||..:|:
 Worm   764 EAQYSIDSSTNLIS-WILKSIEDSKVN-GRSLKMMIKLKDGIEYGK 807

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Naa15-16	NP_573384.1	TPR repeat	13..39	CDD:276809	14/25 (56%)
		TPR	45..269	CDD:440225	105/223 (47%)
		TPR repeat	48..75	CDD:276809	16/26 (62%)
		TPR repeat	83..109	CDD:276809	17/25 (68%)
		TPR repeat	114..144	CDD:276809	17/29 (59%)
		TPR repeat	149..173	CDD:276809	8/23 (35%)
		NatA_aux_su	187..703	CDD:463630	202/520 (39%)
		TPR repeat	410..440	CDD:276809	16/29 (55%)
		TPR repeat	445..470	CDD:276809	13/24 (54%)
hpo-29	NP_497180.3	TPR	28..258	CDD:440225	113/230 (49%)
		TPR repeat	54..81	CDD:276809	16/26 (62%)
		TPR repeat	86..116	CDD:276809	20/29 (69%)
		NatA_aux_su	192..692	CDD:463630	202/519 (39%)
		TPR repeat	385..411	CDD:276809	8/25 (32%)
		TPR repeat	416..446	CDD:276809	16/29 (55%)
		TPR repeat	451..476	CDD:276809	13/24 (54%)