Protein Alignment CG32533 and DHX38

DIOPT Version :10

• Sequence 1: NP_728244.1
• Gene: CG32533 / 32933
• FlyBaseID: FBgn0052533
• Length: 1139
• Species: Drosophila melanogaster
• Sequence 2: NP_054722.2
• Gene: DHX38 / 9785
• HGNCID: 17211
• Length: 1227
• Species: Homo sapiens
• Alignment Length: 675
• Identity: 218/675 - (32%)
• Similarity: 351/675 - (52%)
• Gaps: 97/675 - (14%)

  Fly    72 QPVLPPRLAEAELSSMQPYHRSKHLALRLDADELLQEARDQMQSQFRHILLV------------- 123
            :||:|.:.|.::|:.:.   |.....:|..     :|.:::.::|.:|..|.
Human   428 EPVIPVKDATSDLAIIA---RKGSQTVRKH-----REQKERKKAQHKHWELAGTKLGDIMGVKKE 484

  Fly   124 -----------YLDFRQTEK--------------FQRIRKLRQTQRNLPIARFRKDLREALDTSR 163
                       .:|:|..:|              |.:.:.:.:.::.|||...:::|...:..:.
Human   485 EEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQELLTIIRDNS 549

  Fly   164 VVIVAGDTGCGKSTQVPQYLYDFGYRS---IACTQPRRLACVSLCKRVAHELLDDYGSRVAFQIR 225
            :|||.|:||.||:||:.|||::.||..   |.||||||:|.:|:.|||:.|:..:.|..|.:.||
Human   550 IVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEEMGGNLGEEVGYAIR 614

  Fly   226 FERSRTKLTNILFITEGLLLRQLAVAANLDQYDALILDEIHERNLFGDFLLGVTKCLLRARPQLK 290
            ||...::.|.|.::|:|:|||:....|:||.|.|:|:||.|||:|..|.|.|:.:.::..|..||
Human   615 FEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLFGLLREVVARRSDLK 679

  Fly   291 LILMSATINVELFHGYFGEEGARLVQVPGRLFPIKLRYLPPPALELKAGQATSKRSQRNRIDPAP 355
            ||:.|||::.|.|..:||  ...:..:|||.||:.:.:...|..:..  :|..|:|.:..:..||
Human   680 LIVTSATMDAEKFAAFFG--NVPIFHIPGRTFPVDILFSKTPQEDYV--EAAVKQSLQVHLSGAP 740

  Fly   356 FVQVLSLIDQQYPTSERGDVLIFVSGVNEIESVVEAVHEYATEQTH---WLVLPLHSGQAIAD-Q 416
                             ||:|||:.|..:||...:.:.|:..|..:   ..|||::| |..:| |
Human   741 -----------------GDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYS-QLPSDLQ 787

  Fly   417 SKVFDYAPEGMRKCIVSTNIAETSLTVDGVRFVVDSGKVKEMNFDATCKGQRLKEFWVSKSSADQ 481
            :|:|..||:|:|||||:||||||||||||:.||:|||..|...|:.......|:.:.:|:::|:|
Human   788 AKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQ 852

  Fly   482 RKGRAGRTGPGVCFRLYTAEQY-NAFEAYPTPEIYRVPLDTMLLQMVSMGLPDVRAFPFIEAPET 545
            |.|||||||||.||||||...| |.......|||.|..|..::|.:.|:|:.|:..|.|::.|..
Human   853 RSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLLQFHFMDPPPE 917

  Fly   546 ERIEQTILALKQHCALSVEEKITPLGRSLANLPVELSIGKMLLMGSVFPEVEQLLTLAAMLSV-- 608
            :.:..::..|....||.....:|..||.:...|::.::.|||::........::|.:.:||||
Human   918 DNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLIVSCDMGCSSEILLIVSMLSVPA 982

  Fly   609 --QNPLTNRAHTDQRCVRERESL-ESDHGDLFTLVRLYNVWVQLKMRRDGTRQWCRRLGIEEQRF 670
              ..|......:||  :||:.:: ||||      :...||::|.|.....| .||....|..:..
Human   983 IFYRPKGREEESDQ--IREKFAVPESDH------LTYLNVYLQWKNNNYST-IWCNDHFIHAKAM 1038

  Fly   671 YEVTKLRQQFQRI-------LESCG 688
            .:|.::|.|.:.|       |.|||
Human  1039 RKVREVRAQLKDIMVQQRMSLASCG 1063

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32533	NP_728244.1	HrpA	145..>619	CDD:441249	179/485 (37%)
		OB_NTP_bind	792..897	CDD:400182
DHX38	NP_054722.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	60..320
		HrpA	532..>1146	CDD:441249	203/563 (36%)
		DEAH box	652..655		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1155..1227