Protein Alignment CG32533 and PRP2

DIOPT Version :10

• Sequence 1: NP_728244.1
• Gene: CG32533 / 32933
• FlyBaseID: FBgn0052533
• Length: 1139
• Species: Drosophila melanogaster
• Sequence 2: NP_014408.1
• Gene: PRP2 / 855745
• SGDID: S000005294
• Length: 876
• Species: Saccharomyces cerevisiae
• Alignment Length: 829
• Identity: 228/829 - (27%)
• Similarity: 378/829 - (45%)
• Gaps: 167/829 - (20%)

  Fly   101 DADELLQEARDQMQSQFRHILLVYLDFRQTEKFQRIRKLRQTQRNLPIARFRKDLREALDTSRVV 165
            :.|:||.|.:.|.:::....|       :||: :||..:::.::.||:.:::.:|.:.:..::|:
Yeast   186 EEDDLLPEEKLQYEARLAQAL-------ETEE-KRILTIQEARKLLPVHQYKDELLQEIKKNQVL 242

  Fly   166 IVAGDTGCGKSTQVPQYLYDFGYR-----SIACTQPRRLACVSLCKRVAHELLDDYGSRVAFQIR 225
            |:.|:||.||:||:||||.:.|:.     .||.|||||:|..|:..|||.|:....|..|.:|||
Yeast   243 IIMGETGSGKTTQLPQYLVEDGFTDQGKLQIAITQPRRVAATSVAARVADEMNVVLGKEVGYQIR 307

  Fly   226 FERSRTKLTNIL-FITEGLLLRQLAVAANLDQYDALILDEIHERNLFGDFLLGVTKCLLRARPQL 289
            ||...|....:| ::|:|:|||:....:.|.:|..:::||.|||.|..|.|:|:.|.:|..||.|
Yeast   308 FEDKTTPNKTVLKYMTDGMLLREFLTDSKLSKYSCIMIDEAHERTLATDILIGLLKDILPQRPTL 372

  Fly   290 KLILMSATINVELFHGYFGEEGARLVQVPGRLFPIKLRYLPPPALELKAGQATSKRSQRNRIDPA 354
            ||::.|||:|.:.|..:|  :...:..||||.:|:.:.|...|              :.|.|..|
Yeast   373 KLLISSATMNAKKFSEFF--DNCPIFNVPGRRYPVDIHYTLQP--------------EANYIHAA 421

  Fly   355 PFVQVLSLIDQQYPT-SERGDVLIFVSGVNEIE----SVVEAVHEYATEQTHWLVLPLHSGQAIA 414
                 ::.|.|.:.| |..||:|:|::|..|||    .:.|.:.:..:.....::.|:::.....
Yeast   422 -----ITTIFQIHTTQSLPGDILVFLTGQEEIERTKTKLEEIMSKLGSRTKQMIITPIYANLPQE 481

  Fly   415 DQSKVFDYAPEGMRKCIVSTNIAETSLTVDGVRFVVDSGKVKEMNFDATCKGQRLKEFWVSKSSA 479
            .|.|:|...||..||.:::|||||||||:||:|:|:|.|.|||.::..:....:|.....|::|.
Yeast   482 QQLKIFQPTPENCRKVVLATNIAETSLTIDGIRYVIDPGFVKENSYVPSTGMTQLLTVPCSRASV 546

  Fly   480 DQRKGRAGRTGPGVCFRLYTAEQY-NAFEAYPTPEIYRVPLDTMLLQMVSMGLPDVRAFPFIEAP 543
            |||.|||||.|||.|||::|...| :..|..|.|||.|..|...:|.::|:|:.|:..||.::.|
Yeast   547 DQRAGRAGRVGPGKCFRIFTKWSYLHELELMPKPEITRTNLSNTVLLLLSLGVTDLIKFPLMDKP 611

  Fly   544 ETERIEQTILALKQHCALSVEEKITPLGRSLANLPVELSIGKMLLMGSVFPE----VEQLLTLAA 604
            ....:.:::..|....||:.:..||.||:.:...|.|....|:|...:...:    :|:.||:.:
Yeast   612 SIPTLRKSLENLYILGALNSKGTITRLGKMMCEFPCEPEFAKVLYTAATHEQCQGVLEECLTIVS 676

  Fly   605 MLSVQNPLTNRAHTDQRCVRERESLESDHGDLFTLVRLYNVWVQLKMRRDGTRQWCRRLGIEEQR 669
            ||. :.|.................:||||   ...:.::|.|...|.    :|.||:...|:.:.
Yeast   677 MLH-ETPSLFIGQKRDAAASVLSEVESDH---ILYLEIFNQWRNSKF----SRSWCQDHKIQFKT 733

  Fly   670 FYEVTKLRQQFQRILESCGMVVASDSDSQLTSAERATRHGELRQLKAMKRRQRFEQPRQRKLLKQ 734
            ...|..:|.|..|..|..|:|..:|                                :.|..:..
Yeast   734 MLRVRNIRNQLFRCSEKVGLVEKND--------------------------------QARMKIGN 766

  Fly   735 SAGRVAEDEEEQEEAQGDDMRDVDFRLRFDPRQLALLERSSRLDRHSVVVLLKLLLGSGFYPQLA 799
            .||.:                                  ::|:.|..:         |||...:.
Yeast   767 IAGYI----------------------------------NARITRCFI---------SGFPMNIV 788

  Fly   800 ISDEFNY----CKGGGQQFFHTRLKPFVLQHPNSQFAKHFELLKLTESDLLPKPDFYTPKLPLSK 860
            ......|    ...||..         |..||.|       :|.:...:...:|..|
Yeast   789 QLGPTGYQTMGRSSGGLN---------VSVHPTS-------ILFVNHKEKAQRPSKY-------- 829

  Fly   861 RHQLLCYQSLLETAKPYLINCIRLPAAQTLL-----LFSFAID--TNAG 902
                :.||.|:.|:|.::.:|:.:|..:.|:     :|...||  ||.|
Yeast   830 ----VLYQQLMLTSKEFIRDCLVIPKEEWLIDMVPQIFKDLIDDKTNRG 874

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32533	NP_728244.1	HrpA	145..>619	CDD:441249	167/489 (34%)
		OB_NTP_bind	792..897	CDD:400182	22/113 (19%)
PRP2	NP_014408.1	PTZ00121	<7..174	CDD:173412
		HrpA	223..>738	CDD:441249	178/543 (33%)
		OB_NTP_bind	775..862	CDD:400182	22/123 (18%)