Protein Alignment CG32533 and PRP16

DIOPT Version :10

• Sequence 1: NP_728244.1
• Gene: CG32533 / 32933
• FlyBaseID: FBgn0052533
• Length: 1139
• Species: Drosophila melanogaster
• Sequence 2: NP_013012.3
• Gene: PRP16 / 853961
• SGDID: S000001794
• Length: 1071
• Species: Saccharomyces cerevisiae
• Alignment Length: 748
• Identity: 222/748 - (29%)
• Similarity: 357/748 - (47%)
• Gaps: 133/748 - (17%)

  Fly    39 QAKSRQVGRSLVENEADFWKFVGKYEAMMRSTGQ--PV--------LPPRLAE------------ 81
            :||...|.|::..::|            :|:|.|  |:        :||.|::
Yeast   195 EAKLLPVIRNIDNDDA------------LRNTVQLYPIPLKQRMEWIPPFLSKFALENKVPTSII 247

  Fly    82 -----------AELSSMQPYHR------------SKHLALRLDADELLQEARDQ---MQSQFRHI 120
                       :.||.:.|:..            ||.:|||....|.:|::||.   :.:....:
Yeast   248 IGSISETSSQVSALSMVNPFRNPDSEFSANAKRGSKLVALRRINMEHIQQSRDNTTVLNTAMGEV 312

  Fly   121 LLVYLDFRQTEKF-QRI-----------RKLRQTQRNLPIARFRKDLREALDTSRVVIVAGDTGC 173
            |.:..:.:..:|. |:|           ..::.|:..||:.|.|..|...:..::||::.|:||.
Yeast   313 LGLENNNKAKDKSNQKICDDTALFTPSKDDIKHTKEQLPVFRCRSQLLSLIRENQVVVIIGETGS 377

  Fly   174 GKSTQVPQYLYDFGY-----RSIACTQPRRLACVSLCKRVAHELLDDYGSRVAFQIRFER-SRTK 232
            ||:||:.||||:.||     :||..|||||:|.:|:.||||.|:....|..|.:.||||. :.::
Yeast   378 GKTTQLAQYLYEEGYANDRGKSIVVTQPRRVAAISVAKRVAMEMQVPLGKEVGYSIRFEDVTDSE 442

  Fly   233 LTNILFITEGLLLRQLAVAANLDQYDALILDEIHERNLFGDFLLGVTKCLLRARPQLKLILMSAT 297
            .|.:.|:|:|:|||:..:...||:|..:|:||.|||:|..|.|||..|.||..|..||||:.|||
Yeast   443 CTKLKFVTDGILLRETLLDDTLDKYSCVIIDEAHERSLNTDILLGFFKILLARRRDLKLIITSAT 507

  Fly   298 INVELFHGYFGEEGARLVQVPGRLFPIKLRYLPPPA---LELKAGQATSKRSQRNRIDPAPFVQV 359
            :|.:.|..:||  .|....:|||.||::..|...|.   :|....||..
Yeast   508 MNAKKFSAFFG--NAPQFTIPGRTFPVQTIYTSNPVQDYVEAAVSQAVK---------------- 554

  Fly   360 LSLIDQQYPTSERGDVLIFVSGVNEIESVVEAVHE---------YATEQTHWL----VLPLHSGQ 411
            :.|.:.    ...||:|||::|..:||:..:.:.|         :.|.....:    :||::|..
Yeast   555 IHLAND----CSSGDILIFMTGQEDIETTFDTLQEKFLQVYSKKFGTANFEEINDIEILPIYSAL 615

  Fly   412 AIADQSKVFDYAPEGMRKCIVSTNIAETSLTVDGVRFVVDSGKVKEMNFDATCKGQRLKEFWVSK 476
            ....|.|:|.......||.|::|||||||||:.|:|:|:|.|..|...::.......|....:||
Yeast   616 PADLQFKIFQDLHGTKRKIIIATNIAETSLTIKGIRYVIDCGYSKLKVYNPKIGLDSLVITPISK 680

  Fly   477 SSADQRKGRAGRTGPGVCFRLYTAEQYNAFEAYPT-PEIYRVPLDTMLLQMVSMGLPD-VRAFPF 539
            ::||||.||||||.||..:||||.:.:.......| |||.|..|...||.:.|:.:.| :..|||
Yeast   681 ANADQRSGRAGRTAPGTAYRLYTEDTFKEDMYLQTIPEIQRTNLSNTLLLLKSLDVTDELSKFPF 745

  Fly   540 IEAPETERIEQTILALKQHCALSVEEKITPLGRSLANLPVELSIGKMLLMGSVFPEVEQLLTLAA 604
            |:.|..:....::..|....|:....::||||..:|..|::.|:.|:||:.......:::||:.:
Yeast   746 IDKPPLQTFLSSLYELWFIGAIDTSGQLTPLGLQMAKFPLQPSLSKILLIAVRNGCSDEMLTIVS 810

  Fly   605 MLSV----QNPLTNRAHTDQRCVRERESL-ESDHGDLFTLVRLYNVWVQLKMRRDGTRQWCRRLG 664
            ||||    ..|...:...|  ..|.:..: :|||   .||:.::..|    ...:.:..||.:..
Yeast   811 MLSVPQVFYRPKERQKEAD--IARNKFFIAKSDH---LTLLNVFEQW----RANNFSSHWCNKHF 866

  Fly   665 IEEQRFYEVTKLRQQFQRILESCGM-VVASDSD 696
            ::.:.......:|.|...||:|..: |::|..|
Yeast   867 VQYKSLVRARDIRDQLLTILKSQKIPVISSGKD 899

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32533	NP_728244.1	HrpA	145..>619	CDD:441249	175/501 (35%)
		OB_NTP_bind	792..897	CDD:400182
PRP16	NP_013012.3	HrpA	348..>980	CDD:441249	193/583 (33%)