Protein Alignment CG32533 and YLR419W

DIOPT Version :10

• Sequence 1: NP_728244.1
• Gene: CG32533 / 32933
• FlyBaseID: FBgn0052533
• Length: 1139
• Species: Drosophila melanogaster
• Sequence 2: NP_013523.3
• Gene: YLR419W / 851137
• SGDID: S000004411
• Length: 1435
• Species: Saccharomyces cerevisiae
• Alignment Length: 930
• Identity: 242/930 - (26%)
• Similarity: 415/930 - (44%)
• Gaps: 184/930 - (19%)

  Fly   126 DFRQTEKFQRIRKLRQTQRNLPIARFRKDLREALDTSRVVIVAGDTGCGKSTQVPQYLY------ 184
            ::.:..|....:.::..:..||..:.:|.:.:.::.:.||::.|:||.||||||.|::.
Yeast   584 EYTKRIKSSEYKSMQLVREQLPAWKKQKVIIDIINKNEVVLITGETGSGKSTQVVQFILDFLQKE 648

  Fly   185 --DFGYRSIACTQPRRLACVSLCKRVAHELLDDYGSRVAFQIRFERSRTKLTNILFITEGLLLRQ 247
              |||...|.||||||::.:.|.:||:.|.....|..|.:.||........|.|.|:|.|:|:|.
Yeast   649 KGDFGKTKIVCTQPRRISAIGLAERVSDERCVTCGEEVGYVIRGVNKTKASTRIKFMTTGVLVRL 713

  Fly   248 LAVAANLDQYDALILDEIHERNLFGDFLLGVTKCLLRARPQLKLILMSATINVELFHGYFGEEGA 312
            |..|..:.:...:::||:|||::..|.::.:.|.||.....:|::|||||:||:||..:|  .|.
Yeast   714 LQNARTMLENTIVVIDEVHERSIDTDLIVTLMKNLLHRVRGMKIVLMSATVNVDLFKKFF--PGL 776

  Fly   313 RLVQVPGRLFPI--------------KLR--------------------YLPPPALELKAGQATS 343
            ....:.||.|||              |::                    ||.|        :|.|
Yeast   777 ATCHIEGRTFPITDYFLEDILSDLDFKIKREKALSYDDDSVDERNNDDQYLKP--------RADS 833

  Fly   344 KRSQRNRIDPAPFVQVLSLIDQQY-PTSERGDVLIFVSGVNEIESVVEAVHEYATEQTHWLVLPL 407
            |.....:|:.....||:..:.::. ..::.|.:::|:.||.||......:...:.| ..::||||
Yeast   834 KFFTSGQINYDLLCQVVEYVHKRLKAANDNGSIIVFLPGVGEINKCCNLLANKSNE-ADFMVLPL 897

  Fly   408 HSGQAIADQSKVF-DYAPEGMRKCIVSTNIAETSLTVDGVRFVVDSGKVKEMNFDATCKGQRLKE 471
            ||.....||.:|| .|  .|.||.:|||||||||:|:|.....:|:|:.|.|.::......:|.|
Yeast   898 HSALTPEDQKRVFKKY--HGKRKVVVSTNIAETSITIDDCVATIDTGRAKSMFYNPKDNTTKLIE 960

  Fly   472 FWVSKSSADQRKGRAGRTGPGVCFRLYTAEQY-NAFEAYPTPEIYRVPLDTMLLQMVSMGLPDVR 535
            .::||:...||:|||||...|:.::|::...| |...:.|.|||.|:||:::.|.:.:||:.||:
Yeast   961 SFISKAEVKQRRGRAGRVREGLSYKLFSKNLYENDMISMPIPEIKRIPLESLYLSVKAMGIKDVK 1025

  Fly   536 AF--PFIEAP------ETERIEQTILALKQHCALSVEEKITPLGRSLANLPV-ELSIGKMLLMGS 591
            ||  ..::||      :.|||..||..:.:.     ::.:|.||:.::.:|| :...||:|:.|.
Yeast  1026 AFLSTALDAPPLPALQKAERILTTIGLVDES-----DKSLTQLGQFISLMPVMDSKHGKLLIYGI 1085

  Fly   592 VFPEVEQLLTLAAMLSV---------QNPLTNRAHTDQRCVRERESLE------SDHGDLFTLVR 641
            :|...:..:.|.::|.:         :|               ||.::      ...||||.::.
Yeast  1086 LFGCTDISVLLVSILGIGVLPFIGGFEN---------------REKIKKLLCKYESRGDLFAVLE 1135

  Fly   642 LYNVWVQLKMRRDGT--RQWCRRLGIEEQRFYEVTKLRQQFQRILESCGMVVASDSDSQLTSAER 704
            :...:.::|   |.:  |::.|...:...:..|:.....|:..||:..|.:........::...|
Yeast  1136 IVRDYFKIK---DSSIKRKYLRDNLLSYNKINEIKSSTAQYYSILKDVGFLPMDYKVGSISDLNR 1197

  Fly   705 ATRHGELRQLKAM------KRRQRFEQPRQRKLLKQSAGRVAEDEEEQEEAQGDDMRDVDFRLRF 763
            ..|:.::  |:|:      ....|.:.| ..|.|..|:|.|.:|.|         .:.:.:.:|.
Yeast  1198 NERNFDI--LRAILTGAFYPHIARVQLP-DVKYLSTSSGAVEKDPE---------AKMIKYWIRS 1250

  Fly   764 DPRQLALLERSSRLDRHSVVVLLKLLLGSGFYPQLAISDEFNYCKGGGQQFFHTRLKPFVLQHPN 828
            :..|..|.|..:::.:.:..|.|:.|      |..|.           :.|.|.....|.....|
Yeast  1251 EEYQDKLEEYKTKISQETQKVDLEDL------PLPAT-----------RAFIHPSSVLFSTNSVN 1298

  Fly   829 SQFAKHFELLKLTESDLLPKPDFYTPKLPLSKRHQLLCYQSLLETAKPYLINCIRLPAAQTLLLF 893
            .:.||     .|:|.|   .|.....|:|...::..:.:.:...|.|.||.: :......:||||
Yeast  1299 LEDAK-----LLSEVD---GPISRQSKIPTVVKYPFVLFTTSQVTNKLYLRD-LTPTTTLSLLLF 1354

  Fly   894 SFAIDTNAGIT----QIACDGWLGLDLPMPGSGMELLRRAIELRRRWS------RLLYDKLDD-L 947
            ..||..:.|.|    .|..|.||.:                   |.|.      :.|..:||: :
Yeast  1355 GGAISYDIGGTIHSPGIVVDNWLPI-------------------RTWCKNGVLIKELRTQLDEAI 1400

  Fly   948 KSKQESPSH---SSDDRSSA 964
            :.|.|||.:   |..|.|.|
Yeast  1401 RKKLESPDYAKKSQIDNSGA 1420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32533	NP_728244.1	HrpA	145..>619	CDD:441249	163/536 (30%)
		OB_NTP_bind	792..897	CDD:400182	22/104 (21%)
YLR419W	NP_013523.3	UBA_YLR419W_like	369..409	CDD:270457
		RWD_YLR419W-like	428..532	CDD:467662
		HrpA	600..>1219	CDD:441249	182/656 (28%)
		OB_NTP_bind	1205..>1342	CDD:400182	36/171 (21%)