DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32533 and AT1G58060

DIOPT Version :9

Sequence 1:	NP_001285437.1	Gene:	CG32533 / 32933	FlyBaseID:	FBgn0052533	Length:	1139	Species:	Drosophila melanogaster
Sequence 2:	NP_176103.2	Gene:	AT1G58060 / 842173	AraportID:	AT1G58060	Length:	1459	Species:	Arabidopsis thaliana

Alignment Length:	945	Identity:	275/945 - (29%)
Similarity:	429/945 - (45%)	Gaps:	230/945 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 RQTEKFQRIRKLRQTQRNLPIARFRKDLREALDTSRVVIVAGDTGCGKSTQVPQYLYD------- 185
            ::|:|::.:.|   |:..|||:..:..:.:.|....|::|.|:||.||:|||||::.|
plant   599 KRTQKYKDMLK---TRTALPISEVKNGILQHLKEKDVLVVCGETGSGKTTQVPQFILDDMIDSGH 660

  Fly   186 FGYRSIACTQPRRLACVSLCKRVAHEL------LDDYGSRVAFQIRFERSRTKLTNILFITEGLL 244
            .||.:|.||||||:|.:|:.:|||.|.      |||  |.|.:|:|.|.:|:..|.:||.|.|:|
plant   661 GGYCNIICTQPRRIAAISVAQRVADERCESSPGLDD--SLVGYQVRLESARSDKTRLLFCTTGIL 723

  Fly   245 LRQLAVAANLDQYDALILDEIHERNLFGDFLLGVTKCLLRARP------QLKLILMSATINVELF 303
            ||:||....|:....:|:||:|||:|.|||||.:.|.|:..:.      :||:||||||::.:||
plant   724 LRKLAGDRTLNDVTHIIVDEVHERSLLGDFLLIILKSLIEKQSCDNTSRKLKVILMSATVDADLF 788

  Fly   304 HGYFGEEGARLVQVPGRLFPI----------KLRYLPPP----------ALELKAGQATSKRSQR 348
            ..|||.  ..::...||..|:          .:.||..|          :::.|.|....:|.::
plant   789 SRYFGH--CPVITAQGRTHPVTTHFLEEIYESINYLLAPDSPAALRSDTSIKDKLGSVNDRRGKK 851

  Fly   349 N-------------------------------------------RIDPAPFVQVLSLIDQQYPTS 370
            |                                           |||.....:::..||.   |.
plant   852 NLVLAGWGDDYLLSEDCLNPFYVSSNYNSYSDQTQQNLKRLNEDRIDYELLEELICHIDD---TC 913

  Fly   371 ERGDVLIFVSGVNEIESVVE---AVHEYATEQTHWLVLPLHSGQAIADQSKVFDYAPEGMRKCIV 432
            |.|.:|||:.||.||..:::   |.:.:......|| |||||..|.::|.|||...|:|:||.|.
plant   914 EEGAILIFLPGVAEIYMLLDMLAASYRFRGPAADWL-LPLHSSIASSEQRKVFLRPPKGLRKVIA 977

  Fly   433 STNIAETSLTVDGVRFVVDSGKVKEMNFDATCKGQRLKEFWVSKSSADQRKGRAGRTGPGVCFRL 497
            :|||||||:|:|.|.:|:||||.||..::...|...:.|.|:|:::|.||.|||||..||:||.|
plant   978 ATNIAETSITIDDVVYVIDSGKHKENRYNPQKKLSSMVEDWISQANARQRTGRAGRVKPGICFSL 1042

  Fly   498 YTAEQY-NAFEAYPTPEIYRVPLDTMLLQMVSMGLPDVRAFPF----IEAPETERIEQTILALKQ 557
            ||..:: .....|..||:.|:||..:.||:..:||..::  ||    :|.|....:...|..|.:
plant  1043 YTRYRFEKLMRPYQVPEMLRMPLVELCLQIKLLGLGHIK--PFLSRALEPPSEGAMTSAISLLHE 1105

  Fly   558 HCALSVEEKITPLGRSLANLPVELSIGKMLLMGSVFPEVEQLLTLAAMLSVQNPLTNRAHTDQRC 622
            ..|:..:|::||||..||.|||::.||||||.|.:|..:..:|::||.||.::|........|..
plant  1106 VGAVEGDEELTPLGHHLAKLPVDVLIGKMLLYGGIFGCLSPILSIAAFLSYKSPFIYPKDEKQNV 1170

  Fly   623 VRERESLESDHG-------------DLFTLVRLYNVWVQLKMRR--DGTRQWCRRLGIEEQRFYE 672
            .|.:.:|.||:|             |...::..|:.||::...|  ...:::|....:.......
plant  1171 DRVKLALLSDNGVSSSDLNNNDRQSDHLLMMVAYDKWVKILQERGMKAAQRFCESKFLSSSVMRM 1235

  Fly   673 VTKLRQQFQRILESCGMVVASDSDSQLTSAERATRHGELRQLKAMKRRQRFEQPRQRKLLKQSAG 737
            :..:|.||..:|...|::             ...:.||.                        :|
plant  1236 IRDMRVQFGTLLADIGLI-------------NLPKTGEF------------------------SG 1263

  Fly   738 RVAEDEEEQEEAQGDDMRDVDFRLRFDPRQLALLERSSRLDRHSVVVLLKLLLGSGFYPQLAISD 802
            |..|:            .||.|.   ||.|     ..:...:...||  |.:|.:|.||.:|.:|
plant  1264 RKKEN------------LDVWFS---DPTQ-----PFNMYSQQPEVV--KAILCAGLYPNIAAND 1306

  Fly   803 E------FNYCKGGGQQ------FFHTRLKPFVLQHP---NSQFAKHFELLKLTESDLLPKPDFY 852
            :      ||.....|.|      ::..|.:..:  ||   ||.| |.|:
plant  1307 KGITETTFNSLTKQGNQTKSYSAWYDGRREVHI--HPSSINSNF-KAFQ---------------- 1352

  Fly   853 TPKLPLSKRHQLLCYQSLLETAKPYLINCIRLPAAQTLLLFSFAIDTNAGITQIACDGWLGLDLP 917
                     :..|.:...:||.|.||.: ..:.:..::|||..:|:.:.....:..||||.:..|
plant  1353 ---------NPFLVFLEKVETNKVYLRD-TTIVSPFSILLFGGSINVHHQSGSVTIDGWLKVAAP 1407

  Fly   918 MPGSGMELLRRAIELRRRWSRLLYDKLDDLKSKQE 952
               :...:|.:.:.|      .|:..|.||..|.|
plant  1408 ---AQTAVLFKELRL------TLHSILKDLIRKPE 1433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32533	NP_001285437.1	DEXDc	155..327	CDD:214692	79/200 (40%)
		DEXDc	163..298	CDD:238005	69/153 (45%)
		Helicase_C	358..490	CDD:278689	59/134 (44%)
		HA2	560..640	CDD:214852	32/92 (35%)
		OB_NTP_bind	<792..897	CDD:285018	26/119 (22%)
AT1G58060	NP_176103.2	DSRM	411..492	CDD:214634
		HrpA	574..1371	CDD:224557	258/871 (30%)
		DEXDc	632..782	CDD:238005	68/151 (45%)
		Helicase_C	904..1035	CDD:278689	59/134 (44%)
		HA2	1105..1182	CDD:214852	30/76 (39%)
		OB_NTP_bind	1242..1387	CDD:285018	45/232 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D278674at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820