DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32533 and tdrd9

DIOPT Version :9

Sequence 1:	NP_001285437.1	Gene:	CG32533 / 32933	FlyBaseID:	FBgn0052533	Length:	1139	Species:	Drosophila melanogaster
Sequence 2:	XP_012824154.2	Gene:	tdrd9 / 780352	XenbaseID:	XB-GENE-5893104	Length:	1346	Species:	Xenopus tropicalis

Alignment Length:	721	Identity:	207/721 - (28%)
Similarity:	344/721 - (47%)	Gaps:	94/721 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 RSLVENEADFWKFVGKYEAMMRSTGQPVLPPRLAEAELSSMQPYHRSKHLALRLDADELLQEARD 111
            |.|..::.:.|..:||....::..|....|..:|.....:.:...|.:.|           ::.:
Frog     3 RKLTVDQINDWFTIGKDVTDVKLLGSWSEPSSVATGGREAEESERRYRGL-----------QSEN 56

  Fly   112 QMQSQFRHILLVYLDFRQTEKFQ-------RIRKLRQTQR-----------NLPIARFRKDLREA 158
            ....:||     .::.|:.||::       |.||:.....           .|||.:.|::|...
Frog    57 AYVKEFR-----LVEERELEKYKSCSANTARTRKISTFDALTMPEFDPKYPELPILKSREELIAL 116

  Fly   159 LDTSRVVIVAGDTGCGKSTQVPQYLYDF-----GYRSIACTQPRRLACVSLCKRVAHELLDDYGS 218
            ::.:.||::.|.||.|||||:||::.|:     .|.:|..||||::|..|:...::::.....|.
Frog   117 IENNSVVVIHGATGSGKSTQLPQFILDYLRQHGQYCNIVVTQPRKIAARSIATWISNQRCWTLGG 181

  Fly   219 RVAFQIRFERSRTKLTNILFITEGLLLRQLAVAANLDQYDALILDEIHERNLFGDFLLGVTKCLL 283
            ||.:|:..|:..::.|.::::|.|:||:::..|.:|.::..:.:||:|||....||||.|.:.||
Frog   182 RVGYQVGLEKVASEETQLIYMTTGVLLQKIVSAKSLLEFTHIFIDEVHERTEEMDFLLMVVRKLL 246

  Fly   284 RARPQ-LKLILMSATINVELFHGYFG------EEGARLVQVPGRLFPIKLRYLPP----PALELK 337
            ....: :|:||||||||.:.|..||.      ...|.:.:|.|:...|::.||..    |..::.
Frog   247 CTNSRFVKVILMSATINCKEFADYFAVPVLNKMTPAYIFEVEGKPHDIEVFYLDDLKDIPQAKIA 311

  Fly   338 AGQATSKRSQRNRIDPAPFVQVLSLIDQQYPTS------------ERGDVLIFVSGVNEIESVVE 390
            |..:......:...:.|  ..::.|.|:.....            |...||:|:.|:.||..:.|
Frog   312 AHYSDEPLISKEMYEVA--TSLIHLFDEMEKEELKKGKMSHKAYIESNSVLVFLPGLMEINYMHE 374

  Fly   391 AVHEYATEQTHWLVLPLHSGQAIADQSKVFDYAPEGMRKCIVSTNIAETSLTVDGVRFVVDSGKV 455
            .......::.|  |.||||...:.:|:.||.....|.||.|:||||||:|:||..|::|:|....
Frog   375 LFTNMVQKRLH--VYPLHSSITLDEQNLVFMPPVIGYRKVILSTNIAESSITVPDVKYVIDFCLT 437

  Fly   456 KEMNFDATCKGQRLKEFWVSKSSADQRKGRAGRTGPGVCFRLYTAEQY-NAFEAYPTPEIYRVPL 519
            |.:..|.....|.|:..|.||::.|||||||||...|.|:|....:.: |.......||:.|.||
Frog   438 KTLVCDEETNYQSLRLSWASKTNCDQRKGRAGRVSKGYCYRFVQKDFWKNIIPENVIPEMLRSPL 502

  Fly   520 DTMLL--QMVSMGLPDVRAFPFIEAPETERIEQTILALKQHCALSVEEK----------ITPLGR 572
            .:.:|  :::.||.|.......:..|....||:|||.||:..||:|..|          :|.||:
Frog   503 GSTILKVKLLDMGEPRALLATALSPPNITDIERTILLLKELGALAVSGKRENENPYDGELTFLGK 567

  Fly   573 SLANLPVELSIGKMLLMGSVFPEVEQLLTLAAMLSVQN--PLTNRAHTDQRCVRERESLE-SDHG 634
            .||.|||:|.:||::::|.||..:|:.:.:||.||::|  .:..|...|.  .|.:.|.. |...
Frog   568 VLAQLPVDLQLGKLIVLGHVFGCLEECIIIAAALSLKNFFAMPFRHLLDG--YRSKLSFSGSSRS 630

  Fly   635 DLFTLVRLYNVWV------QLKMRRDGTRQWCRRLGIEEQRFYEVTKLRQQFQRILESCGMVV-- 691
            |...||..:..|.      :|::.:| ..:|.:|...:.:|..||..|....::.:....|.|
Frog   631 DCIALVDAFKSWQSCKERGELRLSKD-ELEWGKRNYFQIKRIREVAALYDDLKKRISHFNMHVTQ 694

  Fly   692 -ASDSD 696
             |.|.|
Frog   695 PARDPD 700

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32533	NP_001285437.1	DEXDc	155..327	CDD:214692	62/183 (34%)
		DEXDc	163..298	CDD:238005	51/140 (36%)
		Helicase_C	358..490	CDD:278689	51/143 (36%)
		HA2	560..640	CDD:214852	30/92 (33%)
		OB_NTP_bind	<792..897	CDD:285018
tdrd9	XP_012824154.2	HrpA	60..>677	CDD:224557	191/628 (30%)
tdrd9	XP_012824154.2	Tudor_TDRD9	872..972	CDD:410502
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D278674at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920