DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32533 and Dqx1

DIOPT Version :9

Sequence 1:	NP_001285437.1	Gene:	CG32533 / 32933	FlyBaseID:	FBgn0052533	Length:	1139	Species:	Drosophila melanogaster
Sequence 2:	XP_038964267.1	Gene:	Dqx1 / 680434	RGDID:	1591766	Length:	780	Species:	Rattus norvegicus

Alignment Length:	821	Identity:	206/821 - (25%)
Similarity:	337/821 - (41%)	Gaps:	152/821 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 KLRQTQRNLPIARFRKDLREALDTS--RVVIVAGDTGCGKSTQVPQYLYDF----GYRS--IACT 194
            :|.:.:|.|||...|....|.|::|  .||:|:|:.|.|||||:||:..:|    |:::  :..|
  Rat    34 ELLEQRRALPIWAARFLFLEHLESSPTGVVLVSGEPGSGKSTQIPQWCAEFALARGFQTGQVTVT 98

  Fly   195 QPRRLACVSLCKRVAHELLDDYGSRVAFQIRFERSRTKLTNILFITEGLLLRQLAVAANLDQYDA 259
            ||..||.:||..|||.|:....|..:.:.|..|......|.:.|..:.|.|:::|.......:..
  Rat    99 QPYPLAAMSLASRVADEMDLTLGHEIGYSIPQEDCTGPNTMLRFCWDRLFLQEVASTRGPGAWSV 163

  Fly   260 LILDEIHERNLFGDFLLGVTK-CLLRARP-QLKLILMSATINVELFHGYFGEE-GARLVQVPGRL 321
            |:|||..||::..|.|.|:.: ..||..| ..::::::.:.....|..::|.. ...:.:.||..
  Rat   164 LVLDEAQERSVASDLLQGLLRDTRLRNLPGDPRVVIVTDSALEPKFQAFWGNSPTVHVPREPGEN 228

  Fly   322 FPIKLRYLPPPALELKAGQATSKRSQRNRIDPAPFVQVLSLIDQQYPTSERGDVLIFVSGVNEI- 385
            ..:..:...|..|...|.||..:..||   :.||                 ||||:::....||
  Rat   229 PTLTYKDTVPADLVEAACQAVLELCQR---EEAP-----------------GDVLVYLPSEEEIS 273

  Fly   386 ---ESVVEAVHEYATEQTHWLVLPLHSGQAIADQSKVFDYAPEGMRKCIVSTNIAETSLTVDGVR 447
               ||:...:...|.......|||||.|...|.|: |::.....:||.:|:..:|:.|.::..::
  Rat   274 LCCESLSREMGMLAVPGPLPRVLPLHPGCGQAIQT-VYEDTDVSVRKIVVTHWLADFSFSLPFIQ 337

  Fly   448 FVVDSG-KVKEM-NFDATCKGQRLKEFWVSKSSADQRKGRAGRTGPGVCFRLYTAEQYNAFEA-- 508
            .|:||| :::.: |.....:.|.|:.  :||..|:.|..||....||.|.|||:....: .||
  Rat   338 HVIDSGLELRSVYNPRIRAESQVLRR--ISKCQAEARLLRARGFPPGTCLRLYSKSTLD-LEAPP 399

  Fly   509 YPTPEIYRVPLDTMLLQMVSMGLPDVRAFPFIEAPETERIEQTILALKQHCALSVEEKITPLGRS 573
            .|.|::....|.:::|.:....:.:.....|::.|..|.:.|.:..|....||..:..::.||..
  Rat   400 LPHPKVCEENLSSLVLLLKRKQIAEPGECHFLDRPAPEALMQALEDLDYLAALDDDGDLSDLGII 464

  Fly   574 LANLPVELSIGKMLLMGSVFPEVEQLLTLAAMLSVQNPLTNRAHTDQRCVRE---RESLESDHGD 635
            |:..|:...:.|.||....|..|:::|||||||:.....|.    ...|..|   |..||...||
  Rat   465 LSEFPLPPELAKALLASCEFNCVDEMLTLAAMLTAAPGFTR----PPLCAGEAALRRGLEHADGD 525

  Fly   636 LFTLVRLYNVWVQLKMRRDGTRQWCRRLGIEEQRFYEVTKLRQQFQRILESCGM---VVASDSDS 697
            ..:|:::|..:||    ......||:..|:..:...:..|||.:...:::...:   :.|..|:.
  Rat   526 HSSLIQVYEAFVQ----SGADETWCQARGLSWEALCQARKLRAELLELMQRIELPLSLPAFGSEQ 586

  Fly   698 QLTSAERATRHGELRQLKAMKRRQRFEQ-----------PRQRKLLKQS---AGRVAEDEEEQEE 748
            .....::|...|..  ||||.||....:           |:...|...|   ||..|..
  Rat   587 NRRDLQKALLSGYF--LKAMMRRGLMSKLPSDSLSTSGWPQTAPLAPYSATQAGITATP------ 643

  Fly   749 AQGDDMRDVDFRLRF---------DPRQLALLERSSRLDRHSVVVLLKLLLGSGFYPQLA---IS 801
                       .|.|         .|..|...|.:...|            |:|.|..|.   ::
  Rat   644 -----------ALAFFIFCASLLSPPMYLCFNEVARDTD------------GTGNYLLLTHKHVA 685

  Fly   802 DEFNYCKGGGQQFFHTRLKP-----FVLQHPNSQFAKHFELLK----LTESDLLPK------PDF 851
            ....||      .:..|..|     :||.|       .|.:.|    .|.|::.|:      |.:
  Rat   686 QLSPYC------VYRNRRTPAQPPTWVLYH-------RFSISKDNCLCTVSEIQPEMLVELAPPY 737

  Fly   852 YTPKLPLSKRHQLLCY--------QSLLETAKP--YLINCI 882
            :...||.|:...||..        .::.|||.|  |...|:
  Rat   738 FLSNLPPSESRDLLNQLREGTEPSAAVTETASPQEYGDGCV 778

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32533	NP_001285437.1	DEXDc	155..327	CDD:214692	52/182 (29%)
		DEXDc	163..298	CDD:238005	45/142 (32%)
		Helicase_C	358..490	CDD:278689	36/137 (26%)
		HA2	560..640	CDD:214852	26/82 (32%)
		OB_NTP_bind	<792..897	CDD:285018	27/119 (23%)
Dqx1	XP_038964267.1	HrpA	15..>601	CDD:224557	160/600 (27%)
Dqx1	XP_038964267.1	OB_NTP_bind	662..737	CDD:400182	19/99 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900