Protein Alignment CG32533 and DHX35

DIOPT Version :10

• Sequence 1: NP_728244.1
• Gene: CG32533 / 32933
• FlyBaseID: FBgn0052533
• Length: 1139
• Species: Drosophila melanogaster
• Sequence 2: NP_068750.2
• Gene: DHX35 / 60625
• HGNCID: 15861
• Length: 703
• Species: Homo sapiens
• Alignment Length: 570
• Identity: 179/570 - (31%)
• Similarity: 303/570 - (53%)
• Gaps: 51/570 - (8%)

  Fly   139 LRQTQRNLPIARFRKDLREALDTSRVVIVAGDTGCGKSTQVPQYLYDFGY----RSIACTQPRRL 199
            :.|.::.||:.:.|..:...::..:.|::.|:||||||||:||||.:.|:    |.:..|||||:
Human    47 IEQQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGVTQPRRV 111

  Fly   200 ACVSLCKRVAHELLDDYGSRVAFQIRFERSRTKL-TNILFITEGLLLRQLAVAANLDQYDALILD 263
            |.|::..|||.|.....|..|.:.|||:....:| |.|.|:|:|:|:|::.|...|.:|..::||
Human   112 AAVTVAGRVAEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVREMMVDPLLTKYSVIMLD 176

  Fly   264 EIHERNLFGDFLLGVTKCLLRARPQLKLILMSATINVELFHGYFGE----EGAR----LVQVPGR 320
            |.|||.|:.|..:|:.|.:.:.|..|:||:.|||::.:.|..:|.:    :.||    ::.|.||
Human   177 EAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDADKFRDFFNQNETSDPARDTCVILTVEGR 241

  Fly   321 LFPIKLRYLPPPALELKAGQATSKRSQRNRIDPAPFVQVLSLIDQQYPTSERGDVLIFVSGVNEI 385
            .||:.:.||..|.                   |......:..:.:.:.|...||||.|::|..|:
Human   242 TFPVDIFYLQSPV-------------------PDYIKSTVETVVKIHQTEGDGDVLAFLTGQEEV 287

  Fly   386 ESVVEAVHEYATE------QTHWLVLPLHSGQAIADQSKVFDYAPEGMRKCIVSTNIAETSLTVD 444
            |:||..:.|.|..      :.|..|||:::|....:|.|||:.....:||.||:||:||||:|:.
Human   288 ETVVSMLIEQARALARTGMKRHLRVLPMYAGLPSFEQMKVFERVSRSVRKVIVATNVAETSITIS 352

  Fly   445 GVRFVVDSGKVKEMNFDATCKGQRLKEFWVSKSSADQRKGRAGRTGPGVCFRLYTAEQYNAFEAY 509
            |:.:|:|.|.||...::.....:.|....||::||:||.||.||:..|.|:||||.|.::.....
Human   353 GIVYVIDCGFVKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRSRSGKCYRLYTEEAFDKLPQS 417

  Fly   510 PTPEIYRVPLDTMLLQMVSMGLPDVRAFPFIEAPETERIEQTILALKQHCALSVEEKIT-PLGRS 573
            ..||:.|..|..::||:.::|:.:|..|.|:..|..:.:.|.:..|.....|..:.::| |||..
Human   418 TVPEMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLGMR 482

  Fly   574 LANLPVELSIGKMLLMGSVFPEVEQLLTLAAMLSVQN----PLTNRAHTDQRCVRERESLESDHG 634
            :|..|:.....||||....|...:::|::|||:.:||    |...::|    .:|.......:.|
Human   483 IAEFPLNPMFAKMLLESGNFGCSQEILSIAAMMQIQNIFVVPPNQKSH----AIRVHRKFAVEEG 543

  Fly   635 DLFTLVRLYNVWVQLKMRRDGTRQWCRRLGIEEQRFYEVTKLRQQFQRIL 684
            |..|::.:|..::  |..:|.  :||:...:..:.......:|:|.:::|
Human   544 DHLTMLNIYEAFI--KHNKDS--KWCQEHFLNYKGLVRAATVREQLKKLL 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32533	NP_728244.1	HrpA	145..>619	CDD:441249	166/497 (33%)
		OB_NTP_bind	792..897	CDD:400182
DHX35	NP_068750.2	HrpA	54..>701	CDD:441249	178/563 (32%)
		DEAH box	176..179		2/2 (100%)