Protein Alignment CG32533 and spn-E

DIOPT Version :9

• Sequence 1: NP_001285437.1
• Gene: CG32533 / 32933
• FlyBaseID: FBgn0052533
• Length: 1139
• Species: Drosophila melanogaster
• Sequence 2: NP_476741.1
• Gene: spn-E / 41919
• FlyBaseID: FBgn0003483
• Length: 1434
• Species: Drosophila melanogaster
• Alignment Length: 1301
• Identity: 284/1301 - (21%)
• Similarity: 484/1301 - (37%)
• Gaps: 395/1301 - (30%)

  Fly    27 FLDHKAELVGLLQA----------------KSRQV-GRSLVENEADFWKFVGKYEAMMRSTGQPV 74
            |.|...||..:..|                ||.:| .|.|:..:. ..|.|.|.:.::..|
  Fly     8 FFDFSKELKRVAAAPQGYISSDPRLMATKFKSSEVPNRELIGTDY-VSKIVAKEKCLLNGT---- 67

  Fly    75 LPPRLAEAELSSMQPYHRSKHLALRLDADELLQEARDQMQSQFRHILLVYLDFRQTEKFQRIRKL 139
                     |.:.||..:.......||.|:      :..:::.|         |..|.:::.|..
  Fly    68 ---------LLNEQPQGKRIRTLDDLDTDD------EGEETEIR---------RDDEYYKKFRFN 108

  Fly   140 RQTQRNLPIARFRKDLREALDTSRVVIVAGDTGCGKSTQVPQYLYDFGYRS-----IACTQPRRL 199
            ....:||.|...|:::..|::...|||:.|:|||||:||||||:.|..|:|     |..|||||:
  Fly   109 LNRDKNLSIYAKREEILAAINAHPVVIIKGETGCGKTTQVPQYILDEAYKSGKYCNIVVTQPRRI 173

  Fly   200 ACVSLCKRVAHELLDDYGSRVAFQIRFERSRT-KLTNILFITEGLLLRQLAVAANLDQYDALILD 263
            |.:|:..||..|......:..:||:...|..: :.|.:|:.|.|:||..|.....|..|..::||
  Fly   174 AAISIANRVCQEREWQQNTVCSFQVGLHRPNSLEDTRLLYCTTGVLLNNLINNKTLTHYTHIVLD 238

  Fly   264 EIHERNLFGDFLLGVTKCLLRARPQ-LKLILMSATINVELFHGYFGEEGARLVQVPGRLFPIKLR 327
            |:|||:...||||.|.:.||....: :|:|||||||:.:....||....:
  Fly   239 EVHERDQNMDFLLIVVRRLLATNSRHVKIILMSATIDAKELSDYFTTTNS--------------- 288

  Fly   328 YLPPPALELKAGQATSKRSQRNRIDPAPF---------------------VQVLSLID------- 364
             :||........:.:.::..|:::....:                     |:::.:||
  Fly   289 -IPPVITTNHRRKHSIEKFYRDQLGSIIWNEEDVGHQQVPEINKHGYRAAVKIIVIIDNMERKAA 352

  Fly   365 ----QQYPTSER-GDVLIFVSGVNEIESVVEAVH---------EYATEQTHWLVLPLHSGQAIAD 415
                |.|..:.| |.||||:.|:.||:::.|.:.         :.:..:...|:.|       .:
  Fly   353 IQSRQSYDEALRYGAVLIFLPGIYEIDTMAENLTCMLENDPNIKVSIVRCFSLMTP-------EN 410

  Fly   416 QSKVFDYAPEGMRKCIVSTNIAETSLTVDGVRFVVDSGKVKEMNFDATCKGQRLKEFWVSKSSAD 480
            |..||:..|.|.||.|::|||||:|:||..|.:|:|....|....|.......|:..|.||::..
  Fly   411 QRDVFNPPPPGFRKIILTTNIAESSITVPDVSYVIDFCLAKVKVTDTASSFSSLRLTWASKANCR 475

  Fly   481 QRKGRAGRTGPGVCFRLYTAEQY-NAFEAYPTPEIYRVPLDTMLL--QMVSMGLP-DVRAFPFIE 541
            ||.||.||...|..:|:.....| .....:..||:.|:||...:|  ::::||.| ::.|.. :.
  Fly   476 QRAGRVGRLRSGRVYRMVNKHFYQREMPEFGIPEMLRLPLQNSVLKAKVLNMGSPVEILALA-LS 539

  Fly   542 APETERIEQTILALKQHCA--LSVEEKITPL-------GRSLANLPVELSIGKMLLMGSVFPEVE 597
            .|....|..|||.||:..|  |:|:....||       |..::.||::....:::::|.:|..:|
  Fly   540 PPNLSDIHNTILLLKEVGALYLTVDGIYDPLDGDLTYWGTIMSRLPLDTRQSRLIILGYIFNMLE 604

  Fly   598 QLLTLAAMLSVQNPLTNRAHTDQRCVRERESLESDHGDLFTLVRLYNVWVQLKMRRDGTRQWCRR 662
            :.:.:||.||.....   ||         |...|..||.|.:..:::         ||:
  Fly   605 EAIIIAAGLSTPGLF---AH---------EGGRSQLGDSFWMHYIFS---------DGS------ 642

  Fly   663 LGIEEQRFYEVTKLRQQFQRILESCGMVVASDSDSQLTSAERATRHGELRQLKAMKRRQRFEQPR 727
             |.:   ...:.::...:..|:|:     ..|.:|.:..|:|.  |..||.||.:
  Fly   643 -GSD---LVAIWRVYLTYLNIVEN-----GHDQESAIRWAKRF--HVSLRSLKEI---------- 686

  Fly   728 QRKLLKQSAGRVAEDEEEQEEAQGDDMRDVDFRLR----------FDPRQLALLERSSRLDRHSV 782
              .||.|                       :.|:|          .:|.|:        :|....
  Fly   687 --HLLVQ-----------------------ELRVRCTHLGLIPFPVNPNQM--------MDDREK 718

  Fly   783 VVLLKLLLGSGFYP--------QLAISDEFNYCKGGG----QQFFHTRLKPFVLQHPNSQFAKH- 834
            .::||:::...|||        ..|.:|...|....|    :..:.|..||..:....::..|.
  Fly   719 AIMLKVIIAGAFYPNYFTRSKESCADTDRNIYQTISGHDPCRTVYFTNFKPAYMGELYTRRIKEL 783

  Fly   835 FELLKLTESDLLPKPD----------FYTPK-----------LPLSKRHQLLCYQSL-------- 870
            |:.:::...::    |          |.|.|           :|:|.|.|...|:::
  Fly   784 FQEVRIPPENM----DVTFQEGSQKVFVTFKQDDWIEGSSKYVPVSGRVQSEVYKAVMMRQNRVE 844

  Fly   871 ----------------------------LETAKPYLINCIRLPAAQTLLLFSFAIDTNAGITQIA 907
                                        :...||..:..:.||:     :|...|..:     |.
  Fly   845 RPIHIMNPSAFMSYVQQRGIGDVIEGRWIPPTKPLNVELLALPS-----VFDKTISGS-----IT 899

  Fly   908 CDGWLGLDLPMPGSGMELLRRAIELRRRWSRLLYDKLDDLK----------------SKQES--- 953
            |....|.....|.|..|.:|...|        :::....|:                :|::|
  Fly   900 CIVNCGKFFFQPQSFEECIRNMSE--------IFNAPQQLRNYVTNASAIAKGMMVLAKRDSYFQ 956

  Fly   954 ------PSHSSDDRSSALWQDLVDY-MALDVAYAIRRLLPADIKRLYTHQAP---SARLAELKEN 1008
                  |.:.| :|....:...:|| ....:...:.||:|.::...|....|   ..|||.::
  Fly   957 RATVIRPENQS-NRQPMFYVRFIDYGNCTLLPMQLMRLMPRELTEQYGDLPPRVFECRLAMVQ-- 1018

  Fly  1009 PFAVDFPMTPNEEKGGLNVSEHVVYSCLAEQQWTTAMDATLRAEPWQCTRCDFE----------- 1062
                     |:....|.|             :|:||.:..|:... ||...|.|
  Fly  1019 ---------PSSVVSGNN-------------RWSTAANDMLKTVA-QCGLIDIEVYSLFNNVAAV 1060

  Fly  1063 ---LEEFDVLEQLVHRSKCKR-------RKAQESRTAKTTSTESSTEVASSSSSHSSGGYYCNSC 1117
               :.:..:.::||....|:|       ||..:.|..:    :.|....|::........|..||
  Fly  1061 LIHMRDGIINDKLVELMLCRRSDEDYMSRKDHDFRLRR----QESARNLSTAQRQQINEEYLRSC 1121

  Fly  1118 K 1118
            :
  Fly  1122 Q 1122

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32533	NP_001285437.1	DEXDc	155..327	CDD:214692	65/178 (37%)
		DEXDc	163..298	CDD:238005	60/141 (43%)
		Helicase_C	358..490	CDD:278689	47/152 (31%)
		HA2	560..640	CDD:214852	22/88 (25%)
		OB_NTP_bind	<792..897	CDD:285018	26/174 (15%)
spn-E	NP_476741.1	HrpA	113..>697	CDD:224557	180/680 (26%)
		TUDOR	892..1016	CDD:395449	24/137 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468045
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D278674at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18934
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850