Protein Alignment CG32533 and cdc28

DIOPT Version :10

• Sequence 1: NP_728244.1
• Gene: CG32533 / 32933
• FlyBaseID: FBgn0052533
• Length: 1139
• Species: Drosophila melanogaster
• Sequence 2: NP_595686.2
• Gene: cdc28 / 2540707
• PomBaseID: SPBC19C2.01
• Length: 1055
• Species: Schizosaccharomyces pombe
• Alignment Length: 760
• Identity: 231/760 - (30%)
• Similarity: 382/760 - (50%)
• Gaps: 85/760 - (11%)

  Fly     5 KKKADEHASSRRRTQINLIEFSFLDHKAELVG--LLQAKSRQV-----------GRSLVENEA-- 54
            ||...::...|.:.|:.::.....|.:....|  |.||:.|::           .|..:|.:|
pombe   237 KKSRQQYLKPRAQQQLEILRREIRDEEQLFAGEKLTQAEIRELEKKKELLRIAEERQRLEKQATE 301

  Fly    55 -----DFWKFVGKYEAMMRSTGQPVLPPR-------------LAEAELSSMQPYHRSKHLALRLD 101
                 |::...||.:   |...:.||..|             :..||....:....:|  ||..|
pombe   302 YQMPEDYFTEQGKLD---RKRKEEVLYQRYKDSNEGEQNEVTMGAAEQQRWEAQQINK--ALLFD 361

  Fly   102 ADELLQEARDQMQSQFRHILLV--YLDFR-------QTEKFQRI---RKLRQTQRNLPIARFRKD 154
            .:|.|.....|....|.....:  .||.:       .|:|...:   :.|..::::||:.:::.|
pombe   362 QNEWLPPGEKQFDFVFDESQQIDFLLDTKLSAENPVDTDKMTDVKVEKSLESSRKSLPVYQYKDD 426

  Fly   155 LREALDTSRVVIVAGDTGCGKSTQVPQYLYDFGY----RSIACTQPRRLACVSLCKRVAHELLDD 215
            |.:|::..:|:::..:||.||:||:||:|::.||    :.|.||||||:|.:|:..|||.|:...
pombe   427 LLKAINEYQVLLIVAETGSGKTTQLPQFLHEAGYTKGNKKICCTQPRRVAAMSVAARVAKEMDVR 491

  Fly   216 YGSRVAFQIRFERSRTKLTNILFITEGLLLRQLAVAANLDQYDALILDEIHERNLFGDFLLGVTK 280
            .|..|.:.||||.:.::.|.|.::|:|:|||:.....:|..|..:|:||.|||.|..|.|.|:.|
pombe   492 LGQEVGYSIRFENATSEKTVIKYLTDGMLLREFLTEPDLASYSVIIIDEAHERTLHTDILFGLVK 556

  Fly   281 CLLRARPQLKLILMSATINVELFHGYFGEEGARLVQVPGRLFPIKLRYLPPPALELKAGQATSKR 345
            .:.|.||.||:::.||||:.|.|..||.|  |.:..||||.:|:.:.|.|.|
pombe   557 DIARFRPDLKVLISSATIDAEKFSAYFDE--APVFYVPGRRYPVDIYYTPQP------------- 606

  Fly   346 SQRNRIDPAPFVQVLSLIDQQYPTSERGDVLIFVSGVNEIESVVEAVHEYAT---EQTHWLVL-P 406
             :.|.|..|     ::.|.|.:.|...||:|:|::|.:|||.:.|.:.|...   ::...::| |
pombe   607 -EANYIQAA-----ITTILQIHTTQPAGDILVFLTGQDEIELMSENMQELCRILGKRIPEIILCP 665

  Fly   407 LHSGQAIADQSKVFDYAPEGMRKCIVSTNIAETSLTVDGVRFVVDSGKVKEMNFDATCKGQRLKE 471
            :::......|:|:||..|.|.||.:::|||||||:|:|||.||:|||.||:..::.....:.|..
pombe   666 IYANLPSELQAKIFDPTPPGARKVVLATNIAETSITIDGVNFVIDSGFVKQNMYNPRTGMESLVS 730

  Fly   472 FWVSKSSADQRKGRAGRTGPGVCFRLYTAEQY-NAFEAYPTPEIYRVPLDTMLLQMVSMGLPDVR 535
            ...|::|||||.|||||.|||.||||||...| |..:...:|||.|..|..::|.:.|:|:.::.
pombe   731 VPCSRASADQRAGRAGRVGPGKCFRLYTRRTYNNELDMVTSPEIQRTNLTNIVLLLKSLGINNLL 795

  Fly   536 AFPFIEAPETERIEQTILALKQHCALSVEEKITPLGRSLANLPVELSIGKMLLMGSVFPEVEQLL 600
            .|.|::||..|.:.:::..|....||:...::|.|||.:|..|.:..:.|.|:..|.:..||::|
pombe   796 DFDFMDAPPPETLMRSLELLYALGALNNRGELTKLGRQMAEFPTDPMLSKSLIASSKYGCVEEVL 860

  Fly   601 TLAAMLSVQNPLTNRAHTD-QRCVRERESLESDHGDLFTLVRLYNVWVQLKMRRDGTRQWCRRLG 664
            ::.:||...:.|..|.... ....:.|.:.....||..||:.::|.||.    .|.:..|.|...
pombe   861 SIVSMLGEASSLFYRPKDKIMEADKARANFTQPGGDHLTLLHIWNEWVD----TDFSYNWARENF 921

  Fly   665 IEEQRFYEVTKLRQQFQRILESCGMVVASDSDSQLTSAERATRHG 709
            ::.:.......:|.|...:.|...:.:.::|...|...::|...|
pombe   922 LQYKSLCRARDVRDQLANLCERVEIELVTNSSESLDPIKKAITAG 966

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32533	NP_728244.1	HrpA	145..>619	CDD:441249	178/482 (37%)
		OB_NTP_bind	792..897	CDD:400182
cdc28	NP_595686.2	PTZ00121	<68..>357	CDD:173412	23/124 (19%)
		DUF4670	<213..322	CDD:464815	17/87 (20%)
		HrpA	417..>1039	CDD:441249	196/575 (34%)