Protein Alignment CG32533 and Dhx29

DIOPT Version :10

• Sequence 1: NP_728244.1
• Gene: CG32533 / 32933
• FlyBaseID: FBgn0052533
• Length: 1139
• Species: Drosophila melanogaster
• Sequence 2: NP_766182.2
• Gene: Dhx29 / 218629
• MGIID: 2145374
• Length: 1365
• Species: Mus musculus
• Alignment Length: 1057
• Identity: 276/1057 - (26%)
• Similarity: 457/1057 - (43%)
• Gaps: 279/1057 - (26%)

  Fly     8 ADEHASSRRRTQINLIEFS-----FLDHKAELVGLLQAKSRQVGRSLVENEADFWKFVGKYEAMM 67
            :||   .::|.::|.:|.:     |:   |:|:..|:.:.:|..:...|:|.      |..|...
Mouse   468 SDE---EKKREELNKMETNKPRDLFI---AKLLNKLKQQQQQQQQQRPESEK------GGSEDPE 520

  Fly    68 RSTGQPVLPPRLAEAELSSMQPYHRSKHLALRLDADELLQEARDQMQSQFRHILLVYLDFRQTEK 132
            .|....|....||..   |::|          ..|::|.     .::|.||.:       :.|.|
Mouse   521 ESWENLVSDEDLAAL---SLEP----------TSAEDLA-----PVRSLFRRL-------QSTPK 560

  Fly   133 FQRIRKLRQTQRNLPIARFRKDLREALDTSRVVIVAGDTGCGKSTQVPQYLY------DFGYR-- 189
            :||:.|.||   .||:.:.|..:.|.|...|||:|||:||.|||||||.:|.      :.|.|
Mouse   561 YQRLLKERQ---QLPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLDECGARKC 622

  Fly   190 SIACTQPRRLACVSLCKRVAHELLDDYG-----SRVAFQIRFERSRTKLTNILFITEGLLLRQLA 249
            :|.||||||::.|||..||..||..:.|     |...:|||.|...::.|.:|:.|.|:|||:|.
Mouse   623 NIVCTQPRRISAVSLATRVCEELGCESGPGGRNSLCGYQIRMESRASESTRLLYCTTGVLLRKLQ 687

  Fly   250 VAANLDQYDALILDEIHERNLFGDFLLGVTKCLLRARPQLKLILMSATINVELFHGYFGEEGARL 314
            ....|.....:|:||:|||::..||||.:.|.:|:.|..|.|||||||::.:.|..||..  ..:
Mouse   688 EDGLLADVSHVIVDEVHERSVQSDFLLVILKEILQKRSDLHLILMSATVDSDKFSTYFTH--CPI 750

  Fly   315 VQVPGRLFPIKLRYLPPPALEL---------------------------KAG------------- 339
            :::.||.:|:::.:|.....|.                           |||
Mouse   751 LRISGRSYPVEVFHLEDIVEETGFVLEKDSEYCQKFLEEEEEITINVTSKAGGVKKYQEYIPVQS 815

  Fly   340 ----------QATSKRSQR-------NRIDPAPFVQVLSLIDQ--QYPTSERGDVLIFVSGVNEI 385
                      |..|.|:|.       ::|:....:::|..:|:  |:...| |.||||:.|:..|
Mouse   816 GASPELNPFYQKYSSRTQHAILYMNPHKINLDLILELLVYLDKSPQFRNIE-GAVLIFLPGLAHI 879

  Fly   386 ESVVEAV---HEYATEQTHWLVLPLHSGQAIADQSKVFDYAPEGMRKCIVSTNIAETSLTVDGVR 447
            :.:.:.:   ..:.:|:  :.|:.|||..:..||:..|.:.|.|:||.:::||||||.:|:..|.
Mouse   880 QQLYDLLSSDRRFYSER--YQVIALHSVLSTQDQAAAFMFPPPGVRKIVLATNIAETGITIPDVV 942

  Fly   448 FVVDSGKVKEMNFDATCKGQRLKEFWVSKSSADQRKGRAGRTGPGVCFRLYTAEQYNAFEAYPTP 512
            ||:|:|:.||..:..:.:...|.|.:|||:||.||:|||||...|.||||||.|::..|..|..|
Mouse   943 FVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRAGRVRDGFCFRLYTRERFEGFLDYSVP 1007

  Fly   513 EIYRVPLDTMLLQMV--SMGLPDVRAFPFIEAPETERIEQTILALKQHCALSVEE-KITPLGRSL 574
            ||.||||:.:.|.::  .:|.|:......::.|:.:.|...:..|::..|....| |:||||:.|
Mouse  1008 EILRVPLEELCLHIMKCDLGSPEDFLSKALDPPQLQVISNAMNLLRKIGACEPNEPKLTPLGQHL 1072

  Fly   575 ANLPVELSIGKMLLMGSVFPEVEQLLTLAAMLSVQNPLTNRAHTDQRCVRERESL---ESDHGDL 636
            |.|||.:.|||||:.|::|..:|.:.||||:::.::|..............:.||   :|||
Mouse  1073 AALPVNVKIGKMLIFGAIFGCLEPVATLAAVMTEKSPFITPIGRKDEADLAKSSLAVADSDH--- 1134

  Fly   637 FTLVRLYNVWVQLK--MRRDGTR---QWCRRLGIEEQRFYEVTKLRQQFQRILESCGMVVASDSD 696
               :.:||.::..|  .:..|.|   .:|:|..:.......:..::|:..:::::.|.   |.|.
Mouse  1135 ---LTIYNAYLGWKKAQQEGGFRSEISYCQRNFLNRTSLLTLEDVKQELMKLVKAAGF---SSSP 1193

  Fly   697 SQLTSAERATRHGELRQLKAMKRRQRFEQPRQRKLLKQSAGRVAEDEEEQEEAQGDDMRDVDFRL 761
            |                                                             :..
Mouse  1194 S-------------------------------------------------------------WEG 1197

  Fly   762 RFDPRQLALLERSSRLDRHSVVVLLKLLLGSGFYPQLA---------ISDEF----NYCKGGGQQ 813
            |..|:.|:..:          :.|||.:|.:|.|..:.         ::::.    ...:|..|
Mouse  1198 RKGPQTLSFQD----------IALLKAVLAAGLYDSVGKIMCTKSVDVTEKLACMVETAQGKAQ- 1251

  Fly   814 FFHTRLKPFVLQHPNSQFAKHFELLKLTESDLLPKPDFYTPKLPLSKRHQLLCYQSLLETAKPYL 878
                       .||:|           ...||              :.:..|.||..:...:.||
Mouse  1252 -----------VHPSS-----------VNRDL--------------QTYGWLLYQEKVRYTRVYL 1280

  Fly   879 INCIRLPAAQTLLLFSFAIDTNAGITQIACDGWLGLDLPMPGSGMELLRRAIELRRRWSRLLYDK 943
            .. ..|.....:|||...|:.......::.|||:....|:          .|.:..:..|:|.|.
Mouse  1281 RE-TTLITPFPVLLFGGDIEVQHRERLLSVDGWIYFQAPV----------KIAVIFKQLRVLIDS 1334

  Fly   944 LDDLKSKQESPSHSSDD 960
            :  |:.|.|:|..|.::
Mouse  1335 V--LRKKLENPKMSLEN 1349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32533	NP_728244.1	HrpA	145..>619	CDD:441249	188/551 (34%)
		OB_NTP_bind	792..897	CDD:400182	18/117 (15%)
Dhx29	NP_766182.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..74
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	174..222
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	235..257
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	500..524		6/29 (21%)
		HrpA	570..>1226	CDD:441249	214/740 (29%)
		DEAH box. /evidence=ECO:0000255|HAMAP-Rule:MF_03068	701..704		2/2 (100%)
		OB_NTP_bind	1212..1298	CDD:400182	21/123 (17%)