Protein Alignment CG32533 and Dhx8

DIOPT Version :10

• Sequence 1: NP_728244.1
• Gene: CG32533 / 32933
• FlyBaseID: FBgn0052533
• Length: 1139
• Species: Drosophila melanogaster
• Sequence 2: NP_659080.2
• Gene: Dhx8 / 217207
• MGIID: 1306823
• Length: 1244
• Species: Mus musculus
• Alignment Length: 871
• Identity: 258/871 - (29%)
• Similarity: 408/871 - (46%)
• Gaps: 155/871 - (17%)

  Fly     9 DEHASSRRRTQI--------------NLI---EFSFLDHKAELVGLL----QAKSRQVGRSLVEN 52
            |:....:|.|:|              |::   ||...|   |..|:|    ..:...:...|||.
Mouse   407 DDSLERKRLTRISDPEKWEIKQMIAANVLSKEEFPDFD---EETGILPKVDDEEDEDLEIELVEE 468

  Fly    53 EADFWKFVGKYE-------------------AMMRST---GQPVLPPRLAEAELSSMQPYHRSKH 95
            |..|.:...|..                   |||:|.   .:..|.....|||:.|: |...:||
Mouse   469 EPPFLRGHTKQSMDMSPIKIVKNPDGSLSQAAMMQSALAKERRELKQAQREAEMDSI-PMGLNKH 532

  Fly    96 LALRLDADELLQEARDQMQSQFRHILLVYLDFRQTEKF-----------QRIRKLRQTQRNLPIA 149
            .     .|.|......|:.:..|.|.::..|..:.:|.           :....:.:.:.:|||.
Mouse   533 W-----VDPLPDAEGRQIAANMRGIGMMPNDIPEWKKHAFGGNKASYGKKTQMSILEQRESLPIY 592

  Fly   150 RFRKDLREALDTSRVVIVAGDTGCGKSTQVPQYLYDFGYRS---IACTQPRRLACVSLCKRVAHE 211
            :.::.|.:|:..::::||.|:||.||:||:.|||.:.||.|   |.||||||:|.:|:.|||:.|
Mouse   593 KLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEE 657

  Fly   212 LLDDYGSRVAFQIRFERSRTKLTNILFITEGLLLRQLAVAANLDQYDALILDEIHERNLFGDFLL 276
            .....|..|.:.||||...:..|.|.::|:|:|||:..:..:|.||..::|||.|||.:..|.|.
Mouse   658 FGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLF 722

  Fly   277 GVTKCLLRARPQLKLILMSATINVELFHGYFGEEGARLVQVPGRLFPIKLRYLPPPALELKAGQA 341
            |:.|..::.|..:|||:.|||::...|..||.|  |.:..:|||.:|:::.|
Mouse   723 GLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYE--APIFTIPGRTYPVEILY------------- 772

  Fly   342 TSKRSQRNRIDPAPFVQVLSLIDQQYPTSERGDVLIFVSGVNEIESVVEAVHE----YATEQTHW 402
             :|..:.:.:| |..:.|:    |.:.|...||:|:|::|..||::..|.::|    ...:....
Mouse   773 -TKEPETDYLD-ASLITVM----QIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPEL 831

  Fly   403 LVLPLHSGQAIADQSKVFDYAPEGMRKCIVSTNIAETSLTVDGVRFVVDSGKVKEMNFDATCKGQ 467
            ::||::|......|:::||.||.|.||.:::|||||||||:||:.:|||.|.||:..:::.....
Mouse   832 IILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGID 896

  Fly   468 RLKEFWVSKSSADQRKGRAGRTGPGVCFRLYTAEQYNAFEAYPT--PEIYRVPLDTMLLQMVSMG 530
            :|....:|::.|.||.|||||||||.|:||||...|.. |...|  |||.|..|.:.:|.:.:||
Mouse   897 QLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRD-EMLTTNVPEIQRTNLASTVLSLKAMG 960

  Fly   531 LPDVRAFPFIEAPETERIEQTILALKQHCALSVEEKITPLGRSLANLPVELSIGKMLLMGSVFPE 595
            :.|:.:|.|::||..|.:...:..|....||..|..:|.|||.:|..|:|..:.|||:|......
Mouse   961 INDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGC 1025

  Fly   596 VEQLLTLAAMLSVQN----PLTNRAHTDQRCVRERESLESDHGDLFTLVRLYNVWVQLKMRRDGT 656
            .|::||:.:||||||    |...:|..||:    :.......||..||:.:||.|...|.    :
Mouse  1026 SEEMLTIVSMLSVQNVFYRPKDKQALADQK----KAKFHQTEGDHLTLLAVYNSWKNNKF----S 1082

  Fly   657 RQWCRRLGIEEQRFYEVTKLRQQFQRILE-------SCGMVVASDSDSQLTSAERATRHGELRQL 714
            ..||....|:.:.......:|:|...|::       |||        ......::|...|..|
Mouse  1083 NPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCG--------KSTVRVQKAICSGFFR-- 1137

  Fly   715 KAMKRRQRFEQPRQ--RKLLKQSA--------------------GRVAEDEEEQEEAQGDDMR-D 756
            .|.|:     .|::  |.|:.|..                    ..|...:|...|....|.| .
Mouse  1138 NAAKK-----DPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWL 1197

  Fly   757 VDFRLRF----DPRQLALLERSSRLD 778
            |:|...|    ||.:|:..::..||:
Mouse  1198 VEFAPAFFKVSDPTKLSKQKKQQRLE 1223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32533	NP_728244.1	HrpA	145..>619	CDD:441249	181/486 (37%)
		OB_NTP_bind	792..897	CDD:400182
Dhx8	NP_659080.2	GH2-like_DHX8	25..92	CDD:409668
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	152..289
		S1_DHX8_helicase	289..367	CDD:240189
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	361..396
		HrpA	580..>1211	CDD:441249	218/675 (32%)
		DEAH box	709..712		2/2 (100%)