Protein Alignment CG32533 and rha-2

DIOPT Version :10

• Sequence 1: NP_728244.1
• Gene: CG32533 / 32933
• FlyBaseID: FBgn0052533
• Length: 1139
• Species: Drosophila melanogaster
• Sequence 2: NP_498895.1
• Gene: rha-2 / 176207
• WormBaseID: WBGene00015525
• Length: 1148
• Species: Caenorhabditis elegans
• Alignment Length: 942
• Identity: 257/942 - (27%)
• Similarity: 415/942 - (44%)
• Gaps: 226/942 - (23%)

  Fly   103 DELLQEARDQMQSQFRHILLV---YLDFRQTEKFQRIRKLRQTQRNLPIARFRKDLR--EALDTS 162
            |:::.:..|..:|....||.:   .:..|:....:|.:::::::..|||  |.:::|  ||::.:
 Worm   190 DQIVVKREDDEESDNEDILALPTTTVINRKKVIVERSKEIQKSRAELPI--FAEEMRIVEAINEN 252

  Fly   163 RVVIVAGDTGCGKSTQVPQYLYDFGYRS----IACTQPRRLACVSLCKRVAHELLDDYGSRVAFQ 223
            .|.:|.|:||.||:||:||:||:.||.|    |..|:|||:|.:::.:||..||...  ..|::|
 Worm   253 LVTVVCGETGSGKTTQIPQFLYEAGYASEGELIGITEPRRVAAIAMAQRVGVELAKP--DEVSYQ 315

  Fly   224 IRFERSRTKLTNILFITEGLLLRQLAVAANLDQYDALILDEIHERNLFGDFLLGVTKCLL----- 283
            ||:|.:|::.|||||:|:|:|::::.....|.:|..:::||.|||:::.|.|:|:...::
 Worm   316 IRYEGTRSETTNILFMTDGVLMKEMEQDVMLKKYSVILIDEAHERSMYSDVLIGMLSRIVPLRSK 380

  Fly   284 RARPQLKLILMSATINVELF--HGYFGEEGARLVQVPGRLFPIKLRY------------------ 328
            .||| |:|::||||:.::.|  ...|.....::::|..|.||:.:.:
 Worm   381 TARP-LRLVIMSATLRLDDFTHKKLFPLLTPKVIKVDARQFPVSVHFEKRTPDDYIASAFRKTCR 444

  Fly   329 ----LPPPA-LELKAGQATSKRSQRNRIDPAPFVQVLSLIDQQYP----TSERGDVLIFVSGVNE 384
                |||.| |....||...|             |:::.:.::||    |.:.|:||  |.|..|
 Worm   445 IHETLPPGAILVFVTGQHEVK-------------QLITKLKKRYPVVYETDKNGEVL--VKGTKE 494

  Fly   385 -IESVVEAVH----EYATEQT-------------------------------------------- 400
             .|..|||..    |...|:|
 Worm   495 WKEKKVEAAKSIKLEDFKEETPETEDFEDVDDGLMDGDDMNERGAAEAFDDYEEFENGDGDLSDG 559

  Fly   401 --------------HWLVLPLHSGQAIADQSKVFDYAPEGMRKCIVSTNIAETSLTVDGVRFVVD 451
                          ....|||:|..::..|.:|||..|.|||.|::|||:||||||:.||::|:|
 Worm   560 KVENSIGAPPADCEPLYCLPLYSLLSMGKQRRVFDETPAGMRLCVISTNVAETSLTIPGVKYVID 624

  Fly   452 SGKVKEMNFDATCKGQRLKEFWVSKSSADQRKGRAGRTGPGVCFRLYTAEQYNAFEAYPTPEIYR 516
            .|..|...:|:.....|.....:|::|.|||.|||||...|..:|||::..|..|..:..|||..
 Worm   625 GGFEKRRLYDSITGVSRFAVCRISQASGDQRAGRAGRISAGHAYRLYSSAVYQDFVKFADPEILS 689

  Fly   517 VPLDTMLLQMVSMGLPDVRAFPFIEAPETERIEQTILALKQHCAL----------SVEEKITPLG 571
            .|.|.::|.:.||.:..|..|||..||:.:.:|.   |.|:.|.|          ..|.:||.||
 Worm   690 KPADQLVLHLKSMNIVKVVNFPFPSAPDEQMLES---AEKRLCRLGALSESTKNGKTEARITKLG 751

  Fly   572 RSLANLPVELSIGKMLLMGSVFPEVEQLLTLAAMLSVQNPL----TNRAHTDQ-------RCVRE 625
            ::||..|:..|..|.:.|......:...:.|.::|||:.||    :.|..|.:       ..::|
 Worm   752 KTLAVFPLAPSYAKFIAMADQHNLMSHAILLISLLSVREPLIPVSSLRGDTPEETKELMKNVLKE 816

  Fly   626 RESLESDH------GDLFTLVRLYNVWVQLKMRRDGTRQWCRRLGIEEQRFYEVTKLRQQFQRIL 684
            |....| |      |||..|:...:|..|:|.   ..|: |.::|:..:...|..|||||...|:
 Worm   817 RRRWCS-HTGARRLGDLKVLMHAASVAEQIKY---NARE-CEKVGLRVKALVEARKLRQQLTNIV 876

  Fly   685 E-SCGM--VVASDSDSQLTSAERATRHGELRQLKAMKRRQRFEQPRQRKLLKQSAGRVAEDEEEQ 746
            . ||..  ..|.|||....:.::|..   |||:.......|         |.:...|....||.|
 Worm   877 NASCKKEHAAALDSDLPPPTDQQAQL---LRQMVVASFSDR---------LARRVDRSVGQEEVQ 929

  Fly   747 EEAQGDDMRDVDFRLRFDPRQLALLERSSRLDRHSVV-VLLKLLLGSGFYPQLAISDEF------ 804
            :.|....:  :...:..||..:...|....:....:| |..|.|:.|    ..|:..|:
 Worm   930 KGAYETTL--IKGHVFIDPCSVVFTEEPEFVIYQELVQVNEKKLMTS----VCAVDKEWLSRLAE 988

  Fly   805 NYCKGG----GQQFFHTRLKPFVL------------QHPNS--------QFAKHFELLKLTESDL 845
            :||..|    .|:..:..:|..|:            :.||.        ...::|.|. |.:..:
 Worm   989 SYCNYGEQDKNQEPIYDPVKDMVVKTVKVTFGPLNWELPNENRSVPHDIMMYRYFALF-LLDGLV 1052

  Fly   846 LPKPDFYTPKL------------PLSKRHQLL 865
            ..|...|||||            .|.||.::|
 Worm  1053 FEKLKEYTPKLLAPPSTMVKSWAKLQKRTEML 1084

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32533	NP_728244.1	HrpA	145..>619	CDD:441249	180/590 (31%)
		OB_NTP_bind	792..897	CDD:400182	24/116 (21%)
rha-2	NP_498895.1	HrpA	234..>1020	CDD:441249	235/831 (28%)