DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kek5 and RLP52

DIOPT Version :9

Sequence 1:	NP_001245746.1	Gene:	kek5 / 32930	FlyBaseID:	FBgn0031016	Length:	931	Species:	Drosophila melanogaster
Sequence 2:	NP_197963.1	Gene:	RLP52 / 832660	AraportID:	AT5G25910	Length:	811	Species:	Arabidopsis thaliana

Alignment Length:	291	Identity:	61/291 - (20%)
Similarity:	104/291 - (35%)	Gaps:	96/291 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 KNKALTKIPQDMSNEMQVLDFAHNQIP-ELRRE---------------------EFLLAGLPNVH 102
            ||.....||:::|..::.:|..|||:. :|.|.                     .|.|..:..:.
plant   475 KNHLSGSIPENISTSVKSIDIGHNQLAGKLPRSLVRISSLEVLNVESNKINDTFPFWLDSMQQLQ 539

  Fly   103 KIFLR-NCTIQEVHREAFKGLHILIELDLSGNRIRELHPGTF-------AGLEKLRNVIINNN-- 157
            .:.|| |.....:::..|..|.|   :|:|||......|..|       ..|.|:.:..:..|
plant   540 VLVLRSNAFHGSINQNGFSKLRI---IDISGNHFNGTLPLDFFVNWTAMFSLGKIEDQYMGTNYM 601

  Fly   158 -------EIEVLPNHLFVN----LSFLSRIEFRNNRL-----RQV----QLHV-------FAG-- 193
                   .|.|:...:.:.    |:..:.|:|..|:.     |.|    :|||       |.|
plant   602 RTNYYSDSIVVMIKGIALEMVRILNTFTTIDFSGNKFEGEIPRSVGLLKELHVLNLSNNGFTGHI 666

  Fly   194 ------TMALSAISLEQNRLSHLHKETFKDLQKLMHLSLQGNAWNCSCELQDFRDFAISKRLYTP 252
                  .:.|.::.:.||:||   .|...:|.||.:|:              :.:|:.::.:...
plant   667 PSSMGNLIELESLDVSQNKLS---GEIPPELGKLSYLA--------------YMNFSQNQFVGLV 714

  Fly   253 PTDCQEPPQLRGKLWSEVPSENFACRPRILG 283
            |...|...|         |..:||..||:.|
plant   715 PGGTQFQTQ---------PCSSFADNPRLFG 736

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kek5	NP_001245746.1	LRR_RI	<76..160	CDD:238064	23/122 (19%)
		leucine-rich repeat	76..100	CDD:275380	8/45 (18%)
		LRR_8	99..159	CDD:290566	15/76 (20%)
		leucine-rich repeat	101..124	CDD:275380	5/23 (22%)
		LRR	122..145	CDD:197688	8/29 (28%)
		leucine-rich repeat	125..148	CDD:275380	7/29 (24%)
		LRR_8	148..207	CDD:290566	18/95 (19%)
		leucine-rich repeat	149..172	CDD:275380	4/35 (11%)
		leucine-rich repeat	173..196	CDD:275380	10/46 (22%)
		LRR_8	197..>229	CDD:290566	10/31 (32%)
		leucine-rich repeat	197..220	CDD:275380	7/22 (32%)
		LRRCT	229..277	CDD:214507	6/47 (13%)
		Ig	296..376	CDD:143165
RLP52	NP_197963.1	PLN00113	30..>575	CDD:331614	23/102 (23%)
		leucine-rich repeat	65..88	CDD:275380
		leucine-rich repeat	89..112	CDD:275380
		leucine-rich repeat	113..137	CDD:275380
		leucine-rich repeat	138..185	CDD:275380
		leucine-rich repeat	162..181	CDD:275380
		leucine-rich repeat	212..236	CDD:275380
		leucine-rich repeat	237..260	CDD:275380
		leucine-rich repeat	261..283	CDD:275380
		leucine-rich repeat	284..307	CDD:275380
		leucine-rich repeat	308..331	CDD:275380
		leucine-rich repeat	332..355	CDD:275380
		leucine-rich repeat	356..379	CDD:275380
		leucine-rich repeat	380..403	CDD:275380
		leucine-rich repeat	404..443	CDD:275380
		leucine-rich repeat	444..467	CDD:275380
		leucine-rich repeat	468..489	CDD:275380	5/13 (38%)
		leucine-rich repeat	490..513	CDD:275380	6/22 (27%)
		leucine-rich repeat	514..535	CDD:275380	2/20 (10%)
		leucine-rich repeat	538..559	CDD:275380	4/20 (20%)
		leucine-rich repeat	560..627	CDD:275380	14/69 (20%)
		leucine-rich repeat	628..651	CDD:275380	5/22 (23%)
		PLN00113	<640..743	CDD:331614	27/123 (22%)
		leucine-rich repeat	652..675	CDD:275380	5/22 (23%)
		leucine-rich repeat	676..699	CDD:275380	9/25 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910