DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek5 and Slitrk1

DIOPT Version :9

Sequence 1:NP_001245746.1 Gene:kek5 / 32930 FlyBaseID:FBgn0031016 Length:931 Species:Drosophila melanogaster
Sequence 2:NP_951020.1 Gene:Slitrk1 / 76965 MGIID:2679446 Length:696 Species:Mus musculus


Alignment Length:285 Identity:63/285 - (22%)
Similarity:116/285 - (40%) Gaps:54/285 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 LLLGVLVVLMALPPPTAGTTDWMQSCGTCHCQWNSGKKSADCKNKALTKI--------------- 67
            :||.:|::..:|.......|..:.....|.|....|....||:.|..|.:               
Mouse     1 MLLWILLLETSLCFAAGNVTGDVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFL 65

  Fly    68 ---------PQDMSNEMQV--LDFAHNQIPELRREEFLLAGLPNVHKIFLRNCTIQEVHREAFKG 121
                     |.:.:|....  |...:|.:.|:....||  ||..|.::.:.|..|:...::.|.|
Mouse    66 HGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFL--GLQLVKRLHINNNKIKSFRKQTFLG 128

  Fly   122 LHILIELDLSGNRIRELHPGTFAGLEKLRNVIINNNEIEVLPNHLFVNLSFLSRIEFRNNRLRQV 186
            |..|..|....|.:|::.||.|..|.||..:|:|:|.|..||.::|..:. ::.::.|.|||:.:
Mouse   129 LDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVP-ITHLDLRGNRLKTL 192

  Fly   187 QLHVFAGTMALSAISLEQNRLSHLHKETFKDLQKLMHLSLQGNAWNCSCELQDFRDFA--ISKRL 249
            .                       ::|..:.:..:..:.|:.|.|:|:|:|...:::.  |.|..
Mouse   193 P-----------------------YEEVLEQIPGIAEILLEDNPWDCTCDLLSLKEWLENIPKNA 234

  Fly   250 YTPPTDCQEPPQLRGKLWSEVPSEN 274
            ......|:.|.:|:||..:|...::
Mouse   235 LIGRVVCEAPTRLQGKDLNETTEQD 259

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek5NP_001245746.1 LRR_RI <76..160 CDD:238064 26/85 (31%)
leucine-rich repeat 76..100 CDD:275380 7/25 (28%)
LRR_8 99..159 CDD:290566 19/59 (32%)
leucine-rich repeat 101..124 CDD:275380 6/22 (27%)
LRR 122..145 CDD:197688 8/22 (36%)
leucine-rich repeat 125..148 CDD:275380 8/22 (36%)
LRR_8 148..207 CDD:290566 13/58 (22%)
leucine-rich repeat 149..172 CDD:275380 8/22 (36%)
leucine-rich repeat 173..196 CDD:275380 4/22 (18%)
LRR_8 197..>229 CDD:290566 2/31 (6%)
leucine-rich repeat 197..220 CDD:275380 1/22 (5%)
LRRCT 229..277 CDD:214507 13/48 (27%)
Ig 296..376 CDD:143165
Slitrk1NP_951020.1 leucine-rich repeat 39..60 CDD:275380 4/20 (20%)
LRR 1 59..80 1/20 (5%)
leucine-rich repeat 62..83 CDD:275380 2/20 (10%)
LRR 2 83..104 5/22 (23%)
leucine-rich repeat 84..107 CDD:275380 7/24 (29%)
LRR 3 106..128 4/21 (19%)
LRR_8 108..166 CDD:290566 19/57 (33%)
leucine-rich repeat 108..131 CDD:275380 6/22 (27%)
LRR 4 131..152 7/20 (35%)
leucine-rich repeat 132..155 CDD:275380 8/22 (36%)
LRR_8 155..213 CDD:290566 15/81 (19%)
LRR 5 155..176 9/20 (45%)
leucine-rich repeat 156..177 CDD:275380 8/20 (40%)
LRR 6 178..199 5/44 (11%)
TPKR_C2 212..>250 CDD:301599 10/37 (27%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 268..317
leucine-rich repeat 356..372 CDD:275380
LRR 7 376..397
leucine-rich repeat 377..400 CDD:275380
LRR 8 400..421
leucine-rich repeat 401..424 CDD:275380
LRR 9 424..445
LRR_8 425..483 CDD:290566
leucine-rich repeat 425..448 CDD:275380
LRR 10 448..469
leucine-rich repeat 449..472 CDD:275380
LRR_8 471..530 CDD:290566
LRR 11 472..493
leucine-rich repeat 473..495 CDD:275380
LRR 12 495..516
leucine-rich repeat 496..520 CDD:275380
TPKR_C2 529..579 CDD:301599
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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