DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek5 and lgi2a

DIOPT Version :9

Sequence 1:NP_001245746.1 Gene:kek5 / 32930 FlyBaseID:FBgn0031016 Length:931 Species:Drosophila melanogaster
Sequence 2:NP_001034730.1 Gene:lgi2a / 654827 ZFINID:ZDB-GENE-060217-2 Length:536 Species:Danio rerio


Alignment Length:262 Identity:53/262 - (20%)
Similarity:100/262 - (38%) Gaps:60/262 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 LLLLGVLVVLMALPPPTAGTTDWMQSC-GTCHCQWNSGKKSADCKNKALTKIPQDMSNEMQVLDF 80
            ::::..|::.:|   |...|......| .:|.|    .|:|..|...:.  :|:.:.|::..|..
Zfish     4 VVIIWALLLYLA---PLGNTAKKAFKCPSSCSC----SKESIICVGSSY--VPRYIPNDVSSLSI 59

  Fly    81 AHNQIPELRREEFLLAGLPNVHKIFLRNCTIQEVHREAFKGLHILIELDLSGNRIRELHPGTFAG 145
            .:....|::  |.:.:.:|::..:.|.:..:..|..:||.||..|..|.:..|:|......:|.|
Zfish    60 VNGTFSEVK--EAMFSHMPSLQLLLLNSNALTTVRDDAFSGLPHLEYLFIENNKIETTSKYSFRG 122

  Fly   146 LEKLRNVIINNNEIEVLPNHLFVNLSFLSRIEFRNNRLRQVQLHVFAGTMALSAISLEQNRLSHL 210
            |..|.::.:.||.|:.||..||:                                          
Zfish   123 LRDLTHLSLANNNIKALPRELFI------------------------------------------ 145

  Fly   211 HKETFKDLQKLMHLSLQGNAWNCSCELQDFRDFAISKRLYTPPTDCQEPPQLRGKLWSEVPSENF 275
                  ||..|:.|.|:||.:.|.|..:....:..|.........|..|.:::||..:::.|.:.
Zfish   146 ------DLDSLIELDLRGNVFECDCRAKWLMMWLKSTNATVSDVLCAGPEEMKGKRLNDMASLHN 204

  Fly   276 AC 277
            .|
Zfish   205 EC 206

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek5NP_001245746.1 LRR_RI <76..160 CDD:238064 20/83 (24%)
leucine-rich repeat 76..100 CDD:275380 3/23 (13%)
LRR_8 99..159 CDD:290566 17/59 (29%)
leucine-rich repeat 101..124 CDD:275380 6/22 (27%)
LRR 122..145 CDD:197688 6/22 (27%)
leucine-rich repeat 125..148 CDD:275380 7/22 (32%)
LRR_8 148..207 CDD:290566 8/58 (14%)
leucine-rich repeat 149..172 CDD:275380 8/22 (36%)
leucine-rich repeat 173..196 CDD:275380 0/22 (0%)
LRR_8 197..>229 CDD:290566 5/31 (16%)
leucine-rich repeat 197..220 CDD:275380 2/22 (9%)
LRRCT 229..277 CDD:214507 9/47 (19%)
Ig 296..376 CDD:143165
lgi2aNP_001034730.1 LRR_8 54..112 CDD:290566 13/59 (22%)
LRR_8 100..158 CDD:290566 20/105 (19%)
LRR_4 100..140 CDD:289563 11/39 (28%)
leucine-rich repeat 102..125 CDD:275378 7/22 (32%)
LRR_4 126..>158 CDD:289563 13/79 (16%)
leucine-rich repeat 126..149 CDD:275378 10/70 (14%)
leucine-rich repeat 150..162 CDD:275378 5/11 (45%)
LRRCT 158..198 CDD:214507 8/39 (21%)
EPTP 210..251 CDD:281697
EPTP 257..297 CDD:281697
EPTP 302..348 CDD:281697
EPTP 351..393 CDD:281697
EPTP 398..439 CDD:281697
EPTP 443..484 CDD:281697
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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